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Scientists look to genetics to explain why GLP-1 drugs work only for some people

https://www.scientificamerican.com/article/why-ozempic-and-wegovy-dont-cause-weight-loss-for-everyone/
2•bookofjoe•3h ago

Comments

bookofjoe•3h ago
https://archive.ph/MrX6f
anovikov•2h ago
Indeed, i have lost 10% of my weight (going from "quite a bit overweight but not obese" to "just barely within normal limit"), and my wife lost whopping 26%, going from obese to totally normal. Idk why.

Show HN: A Telescope-style finder for Zed

https://github.com/zed-industries/zed/discussions/22581
1•the-log-lady•2m ago•0 comments

When the world zigs, zag: Chris Lattner, Jeremy Howard on craftsmanship and AI

https://staskus.io/2025/11/01/when-the-world-zigs-zag/
1•staskus•2m ago•0 comments

Find the Best Beta Testers

1•pillionaut•3m ago•1 comments

Linking Rust Crates, Part 1

http://blog.pnkfx.org/blog/2022/05/12/linking-rust-crates/
1•SteveLauC•4m ago•0 comments

Coinbase CEO flips prediction markets with last-minute earnings call word salad

https://www.fastcompany.com/91433012/coinbase-ceo-brian-armstrong-flips-prediction-markets-with-l...
1•greyface-•9m ago•0 comments

Krita Lands Basic HDR Support on Wayland

https://www.phoronix.com/news/Krita-HDR-Wayland-Support
1•breve•9m ago•0 comments

Chips Need to Chill Out

https://spectrum.ieee.org/thermal-management-chips
1•quapster•10m ago•0 comments

SQLite concurrency and why you should care about it

https://jellyfin.org/posts/SQLite-locking/
2•HunOL•11m ago•0 comments

Abandonware of the web: do you know that there is an HTML tables API?

https://christianheilmann.com/2025/10/08/abandonware-of-the-web-do-you-know-that-there-is-an-html...
11•begoon•12m ago•7 comments

The mystery of why leaves change colour in the autumn

https://www.bbc.com/future/article/20251031-the-mystery-of-why-leaves-change-colour-in-the-autumn
1•giuliomagnifico•12m ago•0 comments

Pitching the Death Star to Investors

https://supremefounder.com/pitching-investors.html
2•fmfamaral•13m ago•0 comments

Bootloader Unlock Wall of Shame

https://github.com/zenfyrdev/bootloader-unlock-wall-of-shame
2•turrini•14m ago•0 comments

Halloween 2025 Stats

https://cruftbox.com/2025/10/31/halloween-2025/
1•FunnyLookinHat•14m ago•0 comments

Show HN: Trying to eat better? I built a nutritional assistant

https://www.chat.eko-bazaar.com/
1•dammsaturn•15m ago•0 comments

The Terrible Technical Architecture of My First Startup

https://blog.jacobstechtavern.com/p/my-terrible-startup-architecture
1•tamnd•15m ago•0 comments

Deep Dive on Multi-Layer Fingerprinting for Modern Bot Detection Research

https://pydoll.tech/docs/deep-dive/fingerprinting/
1•birdculture•17m ago•0 comments

Show HN: C Generic Queue Data Structure

https://github.com/kostakis/Generic-Queue
1•kostakisgr•17m ago•0 comments

How to Solve It: Modern Heuristics

https://archive.org/details/howtosolveitmode0000mich
1•suioir•18m ago•1 comments

Show HN: Modular DDD Core for .NET Microservices

https://github.com/TaskHub-Server/TaskHub.Shared
1•andrey-serdyuk•19m ago•0 comments

Show HN: Chess960v2 – Stockfish tournament with different starting positions

https://chess960v2.com/en
1•lavren1974•21m ago•0 comments

Every Line of Code You Write Is Training Future AI

https://lightcapai.medium.com/constructing-tomorrow-today-fc03223c638b
1•HenryAI•24m ago•1 comments

Show HN: AI SoundCloud

https://app.sonurastudio.com/sketches
2•kindred•24m ago•0 comments

Malloc() vs. MMAP(MAP_SHARED) in Multithreaded Programs

https://carun.github.io/2021/08/13/system-cpu-usage-and-glibc.html
1•fanf2•28m ago•0 comments

The AI debt dilemma hits Big Tech earnings

https://www.axios.com/2025/10/31/ai-meta-oracle-microsoft
2•moose_man•28m ago•1 comments

Import ChatGPT Conversations in Obsidian

https://blog.missioncontroltoolbox.xyz/blog/how-to-import-chatgpt-conversations-in-obsidian
1•awesomepotato•31m ago•0 comments

Ask HN: Would you trust an AI that sees and hears everything you do?

2•aurintex•33m ago•10 comments

Ducking annoying: why has iPhone's autocorrect function gone haywire?

https://www.theguardian.com/technology/2025/nov/01/ducking-annoying-why-has-iphones-autocorrect-f...
1•philk10•33m ago•0 comments

A Reading List on Cartographic Power, Perspective, and Possibility

https://longreads.com/2025/09/16/reading-list-fascination-with-maps/
1•bryanrasmussen•34m ago•0 comments

Why we may not find intentions in the brain

https://www.sciencedirect.com/science/article/abs/pii/S0028393214000220
2•Marshferm•37m ago•0 comments

Show HN: Free unlimited AI video animation with no daily limits or signups

https://animateforever.com/
1•fyrean•38m ago•0 comments