frontpage.
newsnewestaskshowjobs

Made with ♥ by @iamnishanth

Open Source @Github

fp.

Open in hackernews

Scientists have edited a gene that may reduce high cholesterol permanently

https://www.cnn.com/2025/11/08/health/cholesterol-gene-edit-wellness
3•01-_-•2h ago

Comments

ggm•1h ago
I'd love a more mechanistic description of how the gene works at the macro scale. It's doing an edit, fine. How does it get specificity to the liver cells managing homeostatis for hdl and ldl, and how does it get inserted or taken up and how long does the modified state persist and why does it persist or age out...

Judge denies request to exempt Flock footage from Public Records Act

https://www.heraldnet.com/news/judge-denies-request-to-exempt-flock-footage-from-public-records-act/
1•ourmandave•1m ago•0 comments

Why does native UI still matter?

https://zen1th.me/posts/native-ui-still-matters/
1•vitalnodo•3m ago•0 comments

Show HN: DeepShot – NBA game predictor with 70% accuracy using ML and stats

https://github.com/saccofrancesco/deepshot
1•Fr4ncio•6m ago•0 comments

Ask HN: Do you get bots signing up random email addresses to your newsletter?

1•BSTRhino•8m ago•0 comments

Characterizing the American Upper Paleolithic

https://www.science.org/doi/10.1126/sciadv.ady9545
1•bikenaga•11m ago•1 comments

What We Can Learn from Brain Organoids

https://www.nytimes.com/2025/11/06/science/brain-organoids-neurons.html
1•mikhael•16m ago•0 comments

Policy, privacy and post-quantum: anonymous credentials for everyone

https://blog.cloudflare.com/pq-anonymous-credentials/
1•eleye•18m ago•0 comments

CC Switch: Claude Code and Codex Provider Switcher

https://github.com/farion1231/cc-switch
1•amrrs•20m ago•0 comments

Windows Shared PCs with Microsoft Intune

https://www.burgerhout.org/mastering-windows-shared-pcs-with-microsoft-intune/
1•transpute•22m ago•0 comments

Driving TFEL with RP2040: Offloading the CPU step by step (2021)

https://www.zephray.me/post/rpi_pico_driving_el/
2•starkparker•22m ago•0 comments

PeerLLM v0.7.6: The Fastest, Smartest, and Most Purposeful Version Yet

https://blog.peerllm.com/2025/11/02/announcing-v0.7.6.html
1•amrrs•23m ago•0 comments

French lawmakers vote to tax American retirees who benefit from social security

https://www.lemonde.fr/en/politics/article/2025/11/08/french-lawmakers-vote-to-tax-american-retir...
6•geox•27m ago•0 comments

Building an epaper laptop: the monitor

https://peterme.net/building-an-epaper-laptop-the-monitor.html
1•vitalnodo•27m ago•0 comments

TelUI 1.1: New TelUI version Complete with tools to develop good software

1•telui•27m ago•0 comments

Humanity's Endgame

https://www.noemamag.com/humanitys-endgame/
3•marojejian•28m ago•1 comments

Particles that enhance mRNA delivery could reduce vaccine dosage and costs

https://news.mit.edu/2025/particles-enhance-mrna-delivery-could-reduce-vaccine-dosage-costs-1107
2•gmays•28m ago•0 comments

Judge Declares Mistrial in MIT Grad Brothers Ethereum Fraud Case

https://www.bloomberg.com/news/articles/2025-11-08/judge-declares-mistrial-in-mit-grad-brothers-f...
2•aspenmayer•34m ago•1 comments

Melhorar imagem – Melhore fotos com AI – Grátis

https://melhorar-imagem.com
1•zhamin246•35m ago•0 comments

OpenAI: Our new model GPT-5-Codex-Mini – a more cost-efficient GPT-5-Codex

https://github.com/openai/codex/releases/tag/rust-v0.56.0
2•wahnfrieden•37m ago•0 comments

Show HN: Serve 100 Large AI models on a single GPU with low impact to TTFT

https://github.com/leoheuler/flashtensors
2•leonheuler•37m ago•0 comments

Trait-Constrained Enums in Rust

https://blog.csongor.co.uk/gadts-in-rust/
1•todsacerdoti•41m ago•0 comments

NASA's bold new telescope will do more than just hunt for life

https://www.nature.com/articles/s41550-025-02708-2
3•Marshferm•47m ago•2 comments

PrintScreen: Fabricating Highly Customizable Thin-Film Touch-Displays (2014) [video]

https://www.youtube.com/watch?v=LiD7dnqY034
1•starkparker•54m ago•0 comments

Before AI's Kepler Moment – Are LLMs the Epicycles of Intelligence?

https://ashvardanian.com/posts/llm-epicycles/
2•ashvardanian•57m ago•0 comments

Mislabeled wires responsible for two-day IT outage in South Dakota; officials

https://statescoop.com/south-dakota-wiring-issues-two-day-outage/
1•gnabgib•1h ago•0 comments

French Government Created LLM Leaderboard 'Rigged' for Mistral

https://comparia.beta.gouv.fr/ranking
3•salkahfi•1h ago•0 comments

Scientists criticize 'straw man' arguments in Bill Gates climate memo

https://www.theguardian.com/environment/2025/nov/06/bill-gates-climate-memo
3•belter•1h ago•0 comments

What's the Deal with Euler's Identity?

https://lcamtuf.substack.com/p/whats-the-deal-with-eulers-identity
3•treadump•1h ago•0 comments

Nov. 8 is Aaron Swartz day

https://archive.org/details/TheInternetsOwnBoyTheStoryOfAaronSwartz
8•flossposse•1h ago•0 comments

Leading AI Researcher Is Raising $1B to Build AI Models with EQ

https://www.businessinsider.com/researcher-raising-1-billion-to-build-ai-models-with-eq-2025-10
3•gmays•1h ago•0 comments