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AI will not save developer productivity

https://www.infoworld.com/article/4125409/ai-will-not-save-developer-productivity.html
1•indentit•4m ago•0 comments

How I do and don't use agents

https://twitter.com/jessfraz/status/2019975917863661760
1•tosh•10m ago•0 comments

BTDUex Safe? The Back End Withdrawal Anomalies

1•aoijfoqfw•13m ago•0 comments

Show HN: Compile-Time Vibe Coding

https://github.com/Michael-JB/vibecode
2•michaelchicory•16m ago•0 comments

Show HN: Ensemble – macOS App to Manage Claude Code Skills, MCPs, and Claude.md

https://github.com/O0000-code/Ensemble
1•IO0oI•19m ago•1 comments

PR to support XMPP channels in OpenClaw

https://github.com/openclaw/openclaw/pull/9741
1•mickael•19m ago•0 comments

Twenty: A Modern Alternative to Salesforce

https://github.com/twentyhq/twenty
1•tosh•21m ago•0 comments

Raspberry Pi: More memory-driven price rises

https://www.raspberrypi.com/news/more-memory-driven-price-rises/
1•calcifer•27m ago•0 comments

Level Up Your Gaming

https://d4.h5go.life/
1•LinkLens•31m ago•1 comments

Di.day is a movement to encourage people to ditch Big Tech

https://itsfoss.com/news/di-day-celebration/
3•MilnerRoute•32m ago•0 comments

Show HN: AI generated personal affirmations playing when your phone is locked

https://MyAffirmations.Guru
4•alaserm•33m ago•3 comments

Show HN: GTM MCP Server- Let AI Manage Your Google Tag Manager Containers

https://github.com/paolobietolini/gtm-mcp-server
1•paolobietolini•34m ago•0 comments

Launch of X (Twitter) API Pay-per-Use Pricing

https://devcommunity.x.com/t/announcing-the-launch-of-x-api-pay-per-use-pricing/256476
1•thinkingemote•34m ago•0 comments

Facebook seemingly randomly bans tons of users

https://old.reddit.com/r/facebookdisabledme/
1•dirteater_•35m ago•1 comments

Global Bird Count Event

https://www.birdcount.org/
1•downboots•36m ago•0 comments

What Is Ruliology?

https://writings.stephenwolfram.com/2026/01/what-is-ruliology/
2•soheilpro•38m ago•0 comments

Jon Stewart – One of My Favorite People – What Now? with Trevor Noah Podcast [video]

https://www.youtube.com/watch?v=44uC12g9ZVk
2•consumer451•40m ago•0 comments

P2P crypto exchange development company

1•sonniya•54m ago•0 comments

Vocal Guide – belt sing without killing yourself

https://jesperordrup.github.io/vocal-guide/
2•jesperordrup•58m ago•0 comments

Write for Your Readers Even If They Are Agents

https://commonsware.com/blog/2026/02/06/write-for-your-readers-even-if-they-are-agents.html
1•ingve•59m ago•0 comments

Knowledge-Creating LLMs

https://tecunningham.github.io/posts/2026-01-29-knowledge-creating-llms.html
1•salkahfi•1h ago•0 comments

Maple Mono: Smooth your coding flow

https://font.subf.dev/en/
1•signa11•1h ago•0 comments

Sid Meier's System for Real-Time Music Composition and Synthesis

https://patents.google.com/patent/US5496962A/en
1•GaryBluto•1h ago•1 comments

Show HN: Slop News – HN front page now, but it's all slop

https://dosaygo-studio.github.io/hn-front-page-2035/slop-news
7•keepamovin•1h ago•1 comments

Show HN: Empusa – Visual debugger to catch and resume AI agent retry loops

https://github.com/justin55afdfdsf5ds45f4ds5f45ds4/EmpusaAI
1•justinlord•1h ago•0 comments

Show HN: Bitcoin wallet on NXP SE050 secure element, Tor-only open source

https://github.com/0xdeadbeefnetwork/sigil-web
2•sickthecat•1h ago•1 comments

White House Explores Opening Antitrust Probe on Homebuilders

https://www.bloomberg.com/news/articles/2026-02-06/white-house-explores-opening-antitrust-probe-i...
1•petethomas•1h ago•0 comments

Show HN: MindDraft – AI task app with smart actions and auto expense tracking

https://minddraft.ai
2•imthepk•1h ago•0 comments

How do you estimate AI app development costs accurately?

1•insights123•1h ago•0 comments

Going Through Snowden Documents, Part 5

https://libroot.org/posts/going-through-snowden-documents-part-5/
2•goto1•1h ago•0 comments
Open in hackernews

Trying two dozen different psychedelics

https://psychotechnology.substack.com/p/on-trying-two-dozen-different-psychedelics
71•eatitraw•2mo ago

Comments

homeonthemtn•2mo ago
It's unfortunate that the path of psychedelic normalcy just led to people more publicly bragging about surviving one chemical or another like fucked up merit badges.

A single small dose of any given psychedelic can be enough to generate new mental benchmarks to process the world with (love, empathy, timelessness, selflessness, etc)

The drug itself is often irrelevant to the experience and it's impact, but we've unfortunately dragged along the ego of the underworld where each dose needs to be bigger and more exotic for bragging rights. In that light it's just another drug, and quite sad in my opinion.

DonHopkins•2mo ago
It's like a psychedelic hot dog eating contest!

The Great Smoke Off

https://www.youtube.com/watch?v=jCdCfJ3B4ok

woleium•2mo ago
what’s more sad and worrying are the folks doing themselves lasting damage by doing these things in the wrong situation (mentally or physically) and without appropriate guidance.
ux266478•2mo ago
When I was a younger lad, I'd take something like 75 mics of an acid analogue and just have a normal night out. As juvenile male simians are want to do, sometimes that involved getting into a fight. Turns out that is uniquely fun on psychs, even when you lose badly. A couple years later, I took up dropping acid in the dead of night and terrorizing packs of coyotes that prowled the outskirts of town, that was also really fun.

Psychs are just drugs like any other. I think people get too wrapped up in the mysticism of them, or think the debilitating effects of heroic dosing is unique to them. How many uncs in the chat can't smoke weed anymore because it makes them have an awful time emotionally? How do you think dabbing a gram of wax would work out?

zingababba•2mo ago
Lol dude, lets hang out some time.
PaulHoule•2mo ago
I almost saw this movie last night

https://thefilmstage.com/john-lilly-and-the-earth-coincidenc...

but we had a visitor at home and enough to deal with. I read Lilly's books like

https://en.wikipedia.org/wiki/The_Center_of_the_Cyclone

and they were a bit of a hoot as he nearly killed himself multiple times injecting LSD and then testified that LSD was perfectly safe. I've known a few people, all male, who took LSD and developed a sort of "messiah complex" where they felt not a general spiritual "sacrament" experience but rather the opposite and some kind of hypertrophy of narcissism like the 'False Self' that Kohut warns about.

The article mentions 2-C-T-2 which I got in Europe which I understand was the closest people got to a commercially viable psychedelic in that it has a nice stimulant effect (easy walk from the German border to Děčín) and very nice visuals but seems to have little cosmic element so you are sitting on the toilet and feeling like a constipated sinner and that's about it.

Myself I don't have a lot of interest in LSD and company these days because for a while every time I take it it makes me aware of how I have many more nerve endings in my gut than I have on my skin so I feel turned inside out which isn't quite a "bad trip" but isn't very good either. Best thing that happened the last time was I laid down in the leaf litter and watched a pair of snakes having sex but I later picked four ticks off myself.

homeonthemtn•2mo ago
Hypertrophy of narcissism.

I needed this phrase 20 years ago. Very well put.

alehlopeh•2mo ago
Why would anyone inject LSD? Skin contact with a few micrograms is enough to trip.
PaulHoule•2mo ago
Beats me. The only dosage forms I've seen are blotter and sugar cubes, maybe some of the blotter diffuses through the lining of your mouth if you keep it under your tongue but it also works great if you just swallow it -- it's very orally available.

Lilly though had a bad relationship with drugs, he crashed his bike when he was high on ketamine long before ketamine was fashionable.

In the early 1990s accounts of drug experiences on Erowid were mostly positive ("I smoked weed and got high and had a good time") but by the early 2000s it started to look like anti-drug propaganda but I think it was a lower quality tranche of users [1] and you started seeing negative ones ("I took a fistful of random pills, went out on the street, lost motor control and was laying flat on the ground, everybody was really sympathetic until I rolled over and a huge baggie of pills came out of my pocket, then I got kicked by a cop.")

[1] y'all know I am not inclined to believe in natural hierarchies but I think that early adopters of most things are "better" than later adopters however you define "better"

fnord77•2mo ago
It's not fucked up to want to maximize results while minimizing risks.

The drug itself might actually be relevant. I suspect far more people per 100k have had negative reactions to say DMT than mushrooms, due to speed of onset, other receptors hit, etc.

butlike•2mo ago
People don't like to get lost. At least with shrooms/LSD, the reality doesn't melt away around you. I've heard that happens on DMT, which is...unsettling
trallnag•2mo ago
What do you mean by mental benchmarks? LSD and the like are just drugs. Petty weird to make them more than that. What are they in your opinion? I like taking LSD, but I do NOT like it as something "holy" or "otherworldly".
backscratches•2mo ago
> LSD and the like are just drugs.

And near death experiences are just experiences and miracles/murders are just events.

Some people are not spiritual/mystical, others are.

thinkingtoilet•2mo ago
Like everything in the world today, there is a lot of nonsense, pseudoscience (and actual science), influencer garbage, etc... around psychedelics. However, if you are in a good mental space, and in a comfortable and safe location, and the opportunity comes up, you should absolutely have a psychedelic experience if you can. It is one of the pleasures of life. Start with mushrooms. Be sure to start slow, you can always take more, you can never take less. And if you do take more, don't double your original does, that always gets people in trouble.
the_sleaze_•2mo ago
Everything in moderation.

Also don't forget you can couple your psychedelics with valium. (This isn't medical advice)

butlike•2mo ago
Nah, that's no good. I feel like knowing you can "abort a trip" with valium subconsciously primes you for a bad trip. If something difficult comes up, you can always move. Usually I find that's usually akin to the group determining that walking across the park path to the other side has 'better vibes.'
y-curious•2mo ago
Agreed with everything except starting with mushrooms.

I find them wholly unpleasant on the stomach, difficult to dose and quite intense.

If I was recommending psychedelics to people on the internet, which I totally am not, I would recommend LSD. I know I’m in the minority.

butlike•2mo ago
People always used to say 1/8 of shrooms was a dose. I always thought that was far too much. 1/2 of an eighth (1/16??) is where I like to be with shrooms. Also, doing them in friendly company helps. Set and setting and all that
thinkingtoilet•2mo ago
I would argue one gram is a good starter dose. 1/8 is when you start to board the space ship. Half an eighth is a great trip for someone who is comfortable with it.
cannonpr•2mo ago
There is something I don’t entirely understand about psychedelic use. While it might end up being temporary, there is a lot of data that it alters neural structures in fundamental and relatively poorly understood ways. Consciousness itself is very poorly understood. Why take a chemical that is a bit like rolling the dice on how it’s going to modify fundamentally what you are? If you are struggling with severe depression or anxiety or otherwise, I get it… but in most other cases, why? I post this as someone deeply curious about trying them, yet my mind and intellect are things I cherish when it comes to my enjoyment of life.
JimmyBuckets•2mo ago
I think your definition of "understood" is too narrow and perhaps that is your challenge. People have been taking many of these substances (e.g. psilocybin, THC, DMT, etc.) for thousands of years. Their qualitative, long-term effects are extremely well understood by the cultures and peoples that use them. My assumption is that you are WEIRD (forgive me if I am wrong), and the tendency we have is to disregard any data that wasn't created in a Western lab.
JSR_FDED•2mo ago
Just in case…

The acronym WEIRD stands for Western, Educated, Industrialized, Rich, and Democratic, a term used in psychology and behavioral sciences to describe the populations that have historically been the subject of research.

turnsout•2mo ago
TIL, thanks!
DonHopkins•2mo ago
Ok if I call you COUT? ;)
saulpw•2mo ago
You certainly don't have to! But yet for some reason you're deeply curious. Why?
jugg1es•2mo ago
I think there is a misunderstanding about the therapeutic effects of psychedelics. The drugs themselves may alter physical structure in your brain a little bit - but what they really do is temporarily give you a different perspective - they change your point of view. That skewing of perspective is (I believe) where the therapeutic effect from these drugs arises.

If you are deeply curious about these types of drugs, you need to remember that they all wear off eventually. Lots of very smart and happy people have taken these drugs and experienced no harm.

tmn•2mo ago
In my case, the people I looked up to generally had tried these things and reported them as valuable or interesting experiences. So I decided to ‘roll’ the dice and am glad I did.
abraxas•2mo ago
> Why take a chemical that is a bit like rolling the dice on how it’s going to modify fundamentally what you are?

Because sometimes that is the last thing that's left. When everything else has failed it may be the only hope that stands between you and the abyss.

Glamklo•2mo ago
Curiosity.

We only live once.

If your default live model is going to school, then going to unviersity, partner, kids, work, work, living daily live, getting old, dying and you are happy and content, great!

But that image is not true for a lot of people for a lot of different rasons.

LSD gave me a lot of empathy for people who have some mental illness for example. MDMA gave me a very empathic experience i never had before.

And just getting old might be a goal for people, also something like not dying but again, thats just a default thinking not necessarliy what other people conclude for their lives.

dymk•2mo ago
It's fascinating that this particular comment was flagged (I vouched for it).

The reason I took psychedelics the first time was also some combination of curiosity, recreation, and frustration at feeling like I'd fallen into a local min. As a cousin comment mentions, their power is giving you a different perspective which you quite literally cannot conceive of in your current mental state.

Those who have been to therapy (and had a good therapist) know the value that an honest and different outside perspective can have on your life. But there's also a barrier between you and that other person - they don't really have the full context of what motivates or worries you. Psychedelics are a new perspective on the thoughts going through your head, the sensory experience you're having, the emotions you're physically feeling.

That's not to say it's all good and no bad, but I'll leave that to the droves of comments exaggerating their risks. If you're looking for an altered mental state, mushrooms / LSD / MDMA pose far less harm than alcohol or cannabis.

BobaFloutist•2mo ago
> you quite literally cannot conceive of in your current mental state.

I'm open to considering the possibility that I can't conceive of it in my current mental state if you're open to considering the possibility that I can.

The dogmatic way some people speak about the life changing potential of psychedelics is reminiscent of how other people speak of religion. It sounds compelling, but the more detail they go into, the more I grow suspicious that maybe this person just wasn't particularly imaginative in the first place.

I'm not saying that's the case! But it's difficult for me when people are asking me to be open minded (about the possibility that there are insights and truths that I'm literally incapable of accessing without psychoactive substances, which most people agree aren't capable of creating anything that isn't, to a greater or lesser extent, already present in your brain) but use language that categorically deny possibilities outside of their experience (there must be such insights, and no human is capable of arriving there without psychoactive aid, because they personally didn't).

I don't know, I know it's a bit childish for me to feel this way, but it also doesn't feel unreasonable.

greygoo222•2mo ago
Many people take moderate doses of psychedelics and find the experience unremarkable. They just don't feel the urge to post incessantly about it online after.

(A sufficiently high dose will probably get you experiences you "cannot conceive of", assuming you haven't gone through psychosis or delirium, but this is not recommended by most).

greygoo222•2mo ago
MDMA is very neurotoxic. It can be used safely, but should not be advertised as harmless. You certainly cannot be using it nearly as often as alcohol or cannabis.
fallingfrog•2mo ago
The life path of "going to school, then going to unviersity, partner, kids, work, work, living daily live, getting old, dying" is, other than the kids part, utterly horrifying to me and feels like not living at all. Why even bother with life if driving to work and driving home is all youre going to do with it? I am fully of how pretentious this sounds but, the way most people live is an insult to the precious gift of the human spirit.

Of course for many there is no choice. But that only makes it more horrifying not less.

2 weeks ago I took shrooms with my friend, we went to the basement of an arcade and crashed a bdsm costume party, then i spent the night at her place. This weekend, I played music with 4 talented people for 15 hours, and we finally collapsed giggling and covered in sweat at 2:30am. Thats living life! These are the kinds of things you can do if you are willing to take risks. You think I want to retire to a life of watching wheel of fortune? Why???

greygoo222•2mo ago
Dude, most people go to parties and play music sometimes. Most people have friends and hobbies and are not the mindless NPCs you seem to think they are. This does not make you special.
ThePowerOfFuet•2mo ago
What a shitty thing to say.
greygoo222•2mo ago
What's shitty is accusing everyone else of "insulting the human spirit" because you think you're the only person to have hobbies.
adornKey•2mo ago
For sure there are some therapeutic effects when kicking someone who is stuck into totally unknown territory. But as far as I've seen most of these people want to get into a mode to understand something better (themselves, the world, spiritual things...). I think some drugs are good at creating the illusion of understanding something.

As a mathematician I can assure you that the feeling of understanding is an emotion. It's mostly disconnected from truth/false values. People can be emotionally happy, be exited and have a group feeling of understanding - but then you give them a counterexample and it turns out everything was just wrong.

A drug might be able to trigger the emotions, but the things about deeper understandings are most likely just illusions. I think I understood that when some guy who was a very simple mind (he was into sniffing glue - and bummed for alcohol) told me about his wonderful experiences of understanding the world.

WhitneyLand•2mo ago
For some people having a child fundamentally changes their definition of love and their belief in how it’s possible to relate to other human beings.

This is mostly disconnected from true/false values. The facts haven’t really changed. Yet it can be so powerful and rewarding few would trade it regardless of the risks/pain/hardships that can come with it.

Experiences can be profound and change perspectives in a way that’s so rewarding and wholistic it’s really impossible to describe.

Comparing such experiences to math doesn’t really work, apples and oranges.

tejohnso•2mo ago
It comes down to curiosity over caution.

But I think your concern about negative fundamental modification seems higher than the reports suggest it ought to be. There are thousands upon thousands of people who've used these drugs without serious consequence. I'd say that in general they're less of a concern than alcohol.

Here's one link I found supporting my intuition: https://www.psypost.org/scientists-say-psychedelic-drugs-lik...

MisterTea•2mo ago
I am not a psychonaught, only started tripping more recently, and I have only used mushrooms. That being said, I was always anxious about using them as I was very freaked out by the idea of something that can alter your mind instead of merely becoming intoxicated like weed or alcohol. I thought it makes you into antoher person and loose control but that is bullshit - you are fully aware. After my first go I have no fear of them.

The feeling is fantastic, nothing like weed or booze. You feel relaxed and warm in the sense that you want to be around people and talk to people. Like it fills you with love for humanity (I wanted to call my mother and tell her I loved her and so on.) BUT it makes you hyper aware of emotions so be sure your environment is relaxed if you're inexperienced. As you come down you will then start to wrestle with your own buried emotions which can really be a roller coaster. However, as long as the environment is relaxed you will feel safe and be able to handle them.

The trick is go slow for your first time, take a little and see how you feel as it take 30-45 min to kick in (for me 45 min like clock work almost.) Make sure you are in a good mental state. Had a bad week or something really bothering you? Not a good state. Don't trip. Make sure the environment feels safe and relaxed.

lagniappe•2mo ago
You wont encounter that type of change with mushrooms at a conventional dose. Normally when people talk about the change in neural structures etc, this comes from higher order psychedelics, or sometimes lower order psychedelics at heroic dosages. Think of it like electroshock therapy in the sense that enduring this large eustress, change is made.
MisterTea•2mo ago
I merely responded to someone who appears to have a fear of taking them because of the effects and shared my experience. Don't understand the downvotes.
eimrine•2mo ago
If something gets banned so heavily then it might be something good in it. Are there any reasons to trust some well-organized commies who bans anything for everybody for everybody's money for getting more everybody's money? Not all of users are Francis Crick and Paul Erdos kind of person but some of them... are.
brookst•2mo ago
As others have said, some combination of perspective on realistic outcomes and risk/reward.

Every experience we have changes us; every job, every family interaction, every book we read and travel we enjoy (hopefully). Learning musical instruments of foreign languages changes neuronal connections. Is there a goal to maintain a static brain over time? (honest question, reasonable if some people think the answer is "yes").

SJMG•2mo ago
Feynman shared your hesitancy for very similar reasons. He states in Surely You're Joking that he was offered, but never took them.
conradev•2mo ago
At the end of the day: it’s a one way door. That’s what is scary about it. It does change you in an un-reversible way, much like getting a tattoo or getting married or having a child. You will be a different person. Hopefully you like that person!
r0me1•2mo ago
risk vs reward. I've had a few psychedelic experiences, and in my case, they either didn't lead to any significant changes or ended up having positive outcomes. But what I've also learned is that my gut flora has a huge impact on how my brain works. Diet plays a major role in how I feel and think. So while I might still try psychedelics occasionally, I'll avoid certain foods because of the concerns you mentioned.
fallingfrog•2mo ago
Marijuana makes me feel like im living inside of a badly written play where the script was written by a new hire at the last minute, none of the actors know their lines and the plot makes no sense. I dont like it. Alcohol gives me migraines and degrades your body.

But shrooms have low potential for addiction, no hangover and its a pleasant experience. So that's my vice of choice. I take them in moderation in social settings. I generally feel like my mood is lifted and my mind is sharp following a dose.

weregiraffe•2mo ago
>rolling the dice on how it’s going to modify fundamentally what you are?

Rotting in the grave is also going to eventually fundamentally modify what you are. Why care about consistency when it's an illusion?

butlike•2mo ago
That's a little too existential, in my book. After ruminating on reality and existence _a lot_, I feel strongly that caring about consistency and "this" here, right now is the most important. Calling everything an "illusion" is just the body's defense mechanism to not engage something painful in one's life.
mock-possum•2mo ago
Because it feels good.

It’s a shortcut to a wildly unique experience that you might otherwise struggle to achieve, or go a lifetime without finding. It also, in my experience, helps clarify what ‘normal’ is, by giving you first hand experience with something radically different by comparison. And this touches on every part of your being - your physical, mental, and emotional sensations can all be increased, decreased, blended, redirected, synthesized, or otherwise fundamentally altered in ways you might otherwise never even be able to imagine - or may have only previously experienced once or twice and never thought accessible again.

In short, it’s a trip, man.

brailsafe•2mo ago
Most of the people I know who are into them probably were just struggling with a mental health problem, the others are just impulsive and don't seem to consider their actions so carefully. Either way, they seem to be doing ...fine

For me, I'm not really curious at all, but otherwise feel the same way that you do. Pretty content, faults included.

butlike•2mo ago
Like anything in life, you can choose if the juice is worth the squeeze for you. But you have to decide. For me, it was a wonderful experience. I've done psychedelics a few times and do consider LSD one of the more important experiences I've ever had. That being said, I could also see the path where one arrives at reducing it to simply being a mechanism to shove serotonin up a receptor it's not supposed to go up, which screws up the brain.

Like an international vacation, it's really what you get out of the trip, and if you consider the ticket worth the price of admission.

throwawaypqpqp•2mo ago
I’ve done ibogaine recreationally at lowish doses if anyone wants to ask me about it. I don’t think it gets enough attention. Maybe because there’s some danger.
awithrow•2mo ago
I'm less familiar with it. All I really know is that it was on the list of natural medicines that was decriminalized in Colorado. What is the experience like?
throwawaypqpqp•2mo ago
Apologies in advance, I’m on mobile.

I’ve been taking doses of around 600mg ibogaine TA, every 6 months or so, bought online at the first place that comes up in google. You can experience cardiac arrest from taking it, which will quickly kill you, and I based this (IMO) safe dosage on some papers I read. Don’t consider me an authority! And there’s also certain gene mutations that can raise or lower your risk of heart problems, related to how you metabolize ibogaine/noribogaine.

(I have also tried microdosing, based on another paper I read about a woman with bipolar depression. But I don’t have much to report there.)

It’s tough to describe any altered state. But for someone who’s thinking it’s like acid or mushrooms, note that it’s not really fun or pleasant. Your heart beats slower and softer, your body feels weak and uncoordinated, and there’s little to do besides rest.

But the mind is so, so active. And it’s like an excavator. Just pulling things from wherever and throwing them into your mind’s eye. I don’t like therapy and find it tedious and unhelpful, but this feels like years of therapy squished into a 12+ hour trip. Has helped me a lot with my relationships, especially with my mom.

You see a lot of yourself. What’s ugly, what’s beautiful, what’s neutral. You feel somehow distant from your problems but close to your “self”, which makes it more comfortable to face things.

After it’s over there’s a glow and calm that lasts a while. Days, or weeks, or months sometimes. Sleep feels a little more restorative, laughs come a little easier, the dusty baseboards of the mind feel cleaner.

So these are the effects of the lowish doses I’ve been taking. Some day in a safer environment I’d love to do a real full dose. But even at this “low” dose, it’s by far the most powerful drug I’ve ever taken, in a positive way.

y-curious•2mo ago
Why do you do this? Are you an alcoholic? I feel like you should mention your motivation more.

I’ve only heard it being useful in the treatment of alcoholism, I have never tried it because it sounds relatively unpleasant.

throwawaypqpqp•2mo ago
I’m the farthest thing from an alcoholic or addict. I have some depression and anxiety though, some sleep issues, burnout.

My motivation is just to live a happier and more peaceful and healthy life.

rsynnott•2mo ago
I feel like _order_ would matter. Like, surely by #24 you're probably getting a bit bored.
Aerbil313•2mo ago
> A psychedelic medicine company Mindstate Design aims to precision engineer mental states in order to heal mental health problems such as depression. Their plan is to create combinations of chemicals that reliably produce the exact necessary healing states — without the “hit and miss” “heal or bad trip” randomness of individual psychedelics.

> And to discover these they use a LLM-based platform that ingests tens of thousands trip reports online and combines with receptor/chemical interaction data (including affinities).

That's wild.