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The AI-Ready Software Developer: Conclusion – Same Game, Different Dice

https://codemanship.wordpress.com/2026/01/05/the-ai-ready-software-developer-conclusion-same-game...
1•lifeisstillgood•48s ago•0 comments

AI Agent Automates Google Stock Analysis from Financial Reports

https://pardusai.org/view/54c6646b9e273bbe103b76256a91a7f30da624062a8a6eeb16febfe403efd078
1•JasonHEIN•3m ago•0 comments

Voxtral Realtime 4B Pure C Implementation

https://github.com/antirez/voxtral.c
1•andreabat•6m ago•0 comments

I Was Trapped in Chinese Mafia Crypto Slavery [video]

https://www.youtube.com/watch?v=zOcNaWmmn0A
1•mgh2•12m ago•0 comments

U.S. CBP Reported Employee Arrests (FY2020 – FYTD)

https://www.cbp.gov/newsroom/stats/reported-employee-arrests
1•ludicrousdispla•14m ago•0 comments

Show HN: I built a free UCP checker – see if AI agents can find your store

https://ucphub.ai/ucp-store-check/
2•vladeta•19m ago•1 comments

Show HN: SVGV – A Real-Time Vector Video Format for Budget Hardware

https://github.com/thealidev/VectorVision-SVGV
1•thealidev•21m ago•0 comments

Study of 150 developers shows AI generated code no harder to maintain long term

https://www.youtube.com/watch?v=b9EbCb5A408
1•lifeisstillgood•21m ago•0 comments

Spotify now requires premium accounts for developer mode API access

https://www.neowin.net/news/spotify-now-requires-premium-accounts-for-developer-mode-api-access/
1•bundie•24m ago•0 comments

When Albert Einstein Moved to Princeton

https://twitter.com/Math_files/status/2020017485815456224
1•keepamovin•25m ago•0 comments

Agents.md as a Dark Signal

https://joshmock.com/post/2026-agents-md-as-a-dark-signal/
2•birdculture•27m ago•0 comments

System time, clocks, and their syncing in macOS

https://eclecticlight.co/2025/05/21/system-time-clocks-and-their-syncing-in-macos/
1•fanf2•28m ago•0 comments

McCLIM and 7GUIs – Part 1: The Counter

https://turtleware.eu/posts/McCLIM-and-7GUIs---Part-1-The-Counter.html
1•ramenbytes•31m ago•0 comments

So whats the next word, then? Almost-no-math intro to transformer models

https://matthias-kainer.de/blog/posts/so-whats-the-next-word-then-/
1•oesimania•32m ago•0 comments

Ed Zitron: The Hater's Guide to Microsoft

https://bsky.app/profile/edzitron.com/post/3me7ibeym2c2n
2•vintagedave•35m ago•1 comments

UK infants ill after drinking contaminated baby formula of Nestle and Danone

https://www.bbc.com/news/articles/c931rxnwn3lo
1•__natty__•36m ago•0 comments

Show HN: Android-based audio player for seniors – Homer Audio Player

https://homeraudioplayer.app
3•cinusek•36m ago•1 comments

Starter Template for Ory Kratos

https://github.com/Samuelk0nrad/docker-ory
1•samuel_0xK•38m ago•0 comments

LLMs are powerful, but enterprises are deterministic by nature

2•prateekdalal•41m ago•0 comments

Make your iPad 3 a touchscreen for your computer

https://github.com/lemonjesus/ipad-touch-screen
2•0y•46m ago•1 comments

Internationalization and Localization in the Age of Agents

https://myblog.ru/internationalization-and-localization-in-the-age-of-agents
1•xenator•47m ago•0 comments

Building a Custom Clawdbot Workflow to Automate Website Creation

https://seedance2api.org/
1•pekingzcc•49m ago•1 comments

Why the "Taiwan Dome" won't survive a Chinese attack

https://www.lowyinstitute.org/the-interpreter/why-taiwan-dome-won-t-survive-chinese-attack
2•ryan_j_naughton•50m ago•0 comments

Xkcd: Game AIs

https://xkcd.com/1002/
2•ravenical•51m ago•0 comments

Windows 11 is finally killing off legacy printer drivers in 2026

https://www.windowscentral.com/microsoft/windows-11/windows-11-finally-pulls-the-plug-on-legacy-p...
1•ValdikSS•52m ago•0 comments

From Offloading to Engagement (Study on Generative AI)

https://www.mdpi.com/2306-5729/10/11/172
1•boshomi•54m ago•1 comments

AI for People

https://justsitandgrin.im/posts/ai-for-people/
1•dive•55m ago•0 comments

Rome is studded with cannon balls (2022)

https://essenceofrome.com/rome-is-studded-with-cannon-balls
1•thomassmith65•1h ago•0 comments

8-piece tablebase development on Lichess (op1 partial)

https://lichess.org/@/Lichess/blog/op1-partial-8-piece-tablebase-available/1ptPBDpC
2•somethingp•1h ago•0 comments

US to bankroll far-right think tanks in Europe against digital laws

https://www.brusselstimes.com/1957195/us-to-fund-far-right-forces-in-europe-tbtb
5•saubeidl•1h ago•0 comments
Open in hackernews

PBM Drug Pricing Distortion Report

https://www.46brooklyn.com/research/welcome-to-private-label-park-nuf485-8h5kw-wk8y2
33•toomuchtodo•2mo ago

Comments

toomuchtodo•2mo ago
Original title "This drug pricing distortion was supposed to go extinct. It’s never been more alive." reworded for context.

Mods: please feel free to update to your liking.

lotsofpulp•2mo ago
> As long-time industry researchers, we understand that drug affordability is a complicated problem with many cooks in the kitchen that can impact the end cost of a medicine.

As someone who can look up double digit profit margins for Eli Lilly/J&J/Pfizer/Novartis/Novo Nordisk/Abbvie/Merck/etc, it doesn’t look like a complicated problem.

briffle•2mo ago
you should really look up the profit margins of the largest PBM's, but they are now wholely owned by large insurance companies, or pharmacies. They are the middle men, and get a cut (and often rebates for selling over a certain amount)

https://www.drugchannels.net/2025/03/the-top-pharmacy-benefi...

TylerE•2mo ago
It's even worse than that. I have CVS for PBM and getting my prescriptions filled anywhere except a CVS will at least double the cost.
lotsofpulp•2mo ago
The profit margins of UNH/CVS/Cigna/Elevance/Humana/etc are 2% to 3%.

The PBMs are departments of these companies, hence they don’t have profit margins. Prime Therapeutics is owned by the various non profit Blues.

I don’t see how they are relevant. If they are earning more money from medicine, then it is being used to subsidize premiums.

There is a reason the market cap for almost all the pharmaceutical companies are bigger than the managed care organizations. UNH is slightly different because they sell far more high margin healthcare rather than just low margin managed care services.

w10-1•2mo ago
TLDR: Current system rewards price manipulation, resulting in vertical integration to inflate list price & reduce competition. This blog post pulls together data showing how the largest does it.

This issue has been so well-known that it has been addressed in national legislation as early as 1992 and in federal court in 2009, but the new integrated PBM's managed to sidestep regulation and transparency.

Bulk contracts specify price as a percentage of various averages (like driving contracts off LIBOR or federal funds rate), but there are few enough players and prices are private, inviting list price inflation. Contracts are not actually using federally-regulated/defined metrics (WAC, NADAC) but legacy (unregulated) AWP.

The few owners of the main PBM's (roughly matching public capital value):

- Cigna/Evernorth/Express Script: Qualient (most expansive offerings)

- CVS: Cordavis

- UnitedHealth/Optum: Nuvaila

Integrated players give themselves a discount but charge others inflated rates. The insurers might also patients charge more for going to out-of-network pharmacies. Both are relatively normal mechanisms to capture benefits of integration.

Very helpful post (but structural solutions out of scope)