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The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•1m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•3m ago•2 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
1•sara_builds•4m ago•0 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•5m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•8m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•9m ago•0 comments

Hello

1•otrebladih•10m ago•0 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•13m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•15m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•17m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•19m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•23m ago•0 comments

.72% Variance Lance

1•mav5431•24m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•26m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•26m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•26m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•28m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•29m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•29m ago•1 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•29m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•30m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
2•layer8•30m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•32m ago•2 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•33m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•34m ago•0 comments

Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
1•hendler•34m ago•0 comments

Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
2•Bender•39m ago•0 comments

Brooklyn cemetery plans human composting option, stirring interest and debate

https://www.cbsnews.com/newyork/news/brooklyn-green-wood-cemetery-human-composting/
1•geox•39m ago•0 comments

Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
1•paulpauper•40m ago•0 comments

Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
1•gmays•41m ago•0 comments
Open in hackernews

Is our death from a hydrogen sulfide event inevitable in climate warming? (2005)

https://www.psu.edu/news/research/story/global-warming-led-climatic-hydrogen-sulfide-and-permian-extinction
28•DrierCycle•2mo ago

Comments

metalman•2mo ago
this is one of several "failure modes" connected to climate change that are bieng dissmissed out of hand and in spite of all the blither blather about humans determining our own future as seperate from anything as trivial as the "weather", we exist as the prime exploiter of what can be summed up as the carbohydrate production of nature, a single number of X millions of tons per anum, which our breathable atmosphere, is a byproduct of.
OgsyedIE•2mo ago
There is no candidate for the prime exploiter of NPP at this time, since any numeric measure of chemical throughput has us almost tied with marine protists.

Furthermore, the majority of calories consumed by humans are derived from the Haber-Bosch process, which entails exploiting ancient reserves of stored sunlight instead of the present-day supply of sunlight.

OgsyedIE•2mo ago
(2010) should be in the title, presumably?
perihelions•2mo ago
> "Today, there are not enough organics in the oceans to go anoxic," says Kump. "But in the Permian,"

The editorialized HN title misrepresents what the article says.

DrierCycle•2mo ago
Have you talked with an oceans specialist recently? Anoxic events are difficult to predict. Not all specialists agree with that Permian isolation.

https://agupubs.onlinelibrary.wiley.com/doi/full/10.1029/202...

masfuerte•2mo ago
That's interesting, but the title still misrepresents the article. Flagged.
DrierCycle•2mo ago
As the issue now includes a deepening of recent radical shift potential in equator-to-pole gradient, the chances for this are now measurably distinct.

The question is left open, particularly in the recent data on gulfstream collapse, which may be imminent.

I'm not sure anyone is qualified to claim 100% anoxic events and hydrogen sulfide out gas are limited to the Permian condition.

https://www.nature.com/articles/s43247-025-02793-1

and

https://agupubs.onlinelibrary.wiley.com/doi/full/10.1029/200...

are in conflict.

acetofenone•2mo ago
My main concern is the acidification of the ocean due to the carbon dioxide equilibrium between the atmosphere and the sea. There is a threshold level threshold at wich the shell of plankton just dissolves. After that happens I think the whole ocean ecosystem will collapse (maybe no more fishes?) Also the deep ocean has an inertia of thousands years meaning that we are going to stick with industrial coal revolution levels of co2 in the atmosphere for a lot of time even if we emit nothing.

People wasn't seeing immediate effects because it was hidden in saturating the ocean and now there's no way back in my opinion

asah•2mo ago
Competing species (non-calcifying) then take over...
consumer451•2mo ago
Will those species replace plankton's role of producing the majority of the Earth's oxygen?
bryanlarsen•2mo ago
After a few million years, sure.
M95D•2mo ago
What you probably don't know yet is that ocean calcifying organisms are the only ones left that still remove CO2 from the atmosphere long term.

Trees take CO2, but when they die, bacteria and fungi oxidize the wood back to CO2. Same for everything else that's greenwashed as "removing CO2". That removal is temporary - only a few years or decades at most.

Without the oceans to trap CO2 into new limestone deposits, we're doomed and we can do absolutely nothing about it.

rstuart4133•2mo ago
It's not the only mechanism for CO2 removal. There is also a geo cycle. I've forgotten the exact details, but it involves the acidity created by CO2 increasing the speed of rock weathering, and the result sediments being incorporated into the plates, plate tectonics removing the carbon from the upper crust and volcanoes re-introducing it. It's self regulating but very slow, taking millions of years.

Granted, biological removal is much faster, now. But during snowball earth in particular there was so little biological activity the geo cycles dominated CO2 regulation.

Neither of those two mechanisms are relevant right now, as mankind's production of CO2 has swamped both mechanisms. That will stop one way or another of course.

lowdownbutter•2mo ago
I've not read and am instead trusting Betteridge's law of headlines.
gmuslera•2mo ago
If will be avoided if we die before, i.e. because the conditions that would eventually lead to that event.

We are changing the environment and the conditions very fast, the Permian process could had taken from hundreds of thousands to millions of years. And CO2 levels because the eruptions that started this were in the order of several thousands, in a process that took also hundreds of thousands of years.

But we are in the road to reach those numbers within decades or very few centuries. If the trend continues, we will die, but by (multiple) other reasons.

bikenaga•2mo ago
Original article: "Massive release of hydrogen sulfide to the surface ocean and atmosphere during intervals of oceanic anoxia" - https://www.researchgate.net/publication/253144294_Massive_r...

Abstract: "Simple calculations show that if deep-water H2S concentrations increased beyond a critical threshold during oceanic anoxic intervals of Earth history, the chemocline separating sulfidic deep waters from oxygenated surface waters could have risen abruptly to the ocean surface (a chemocline upward excursion). Atmospheric photochemical modeling indicates that resulting fluxes of H2S to the atmosphere (>2000 times the small modern flux from volcanoes) would likely have led to toxic levels of H2S in the atmosphere. Moreover, the ozone shield would have been destroyed, and methane levels would have risen to >100 ppm. We thus propose (1) chemocline upward excursion as a kill mechanism during the end-Permian, Late Devonian, and Cenomanian Turonian extinctions, and (2) persistently high atmospheric H2S levels as a factor that impeded evolution of eukaryotic life on land during the Proterozoic."

Related: "Impacts of a massive release of methane and hydrogen sulfide on oxygen and ozone during the late Permian mass extinction" - https://www.sciencedirect.com/science/article/abs/pii/S09218...

in-tension•2mo ago
Given this proposed series of events, what would be the mechanism s that would return the environment to the conditions we see today?