I would think eventually all of the additional positives of the drug will resolve to obesity is bad and reducing obesity has health benefits. Which should be perfectly fine as its valid and results in massive positives in both health and quality of life.
KittenInABox•13m ago
Why would Ozempic, a chemical affecting a specific receptor found in specific parts of the body, affect alzheimer's? I'm just asking questions here I don't understand what the mechanism of action is that this would be disappointing news.
jfarina•12m ago
Maybe because poor diet has been linked to alzheimers?
foobiekr•11m ago
"Type 3 diabetes" is one of the speculated causes of alzheimer's. The evidence there is not great.
I know we can tell that a chemical does a particular thing in the body, but can we tell that it does not do anything other than that thing? The body is ridiculously complex, and as far as I know we don’t know how every part (or combination of parts) works.
Edit: I mean in the theoretical “this targets the x receptor” kind of way, not in “we tested this and found no causal link” way.
KittenInABox•5m ago
That's why I'm genuinely asking why this would be disappointing, like what was the evidence that this does affect Alzheimer's. You would expect by default X does not affect Y by default, so clearly there had to be a theory why you'd spend 2 years on a study to rule it out.
wonderwonder•16m ago