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Ozempic 2.0 is on the way, and it could be even more transformative

https://www.washingtonpost.com/health/2025/11/27/weight-loss-drugs-ozempic-pills-shots/
4•bookofjoe•44m ago

Comments

bookofjoe•43m ago
https://archive.ph/rDzi6
xenospn•37m ago
“Ozempic 2.0 Odyssey MAX”
bookofjoe•18m ago
Pro
paulpauper•3m ago
At this point given the rapid innovation it's rational to stay overweight until the drugs have become optimized,and then endure fewer side effects and faster and more weight loss.

The Beef Programming Language

https://www.beeflang.org/
1•andsoitis•2m ago•0 comments

Ex150nosauce+ACV-2 review: Blasted through plateau, new record low weight

https://www.exfatloss.com/p/ex150nosauceacv-2-review-blasted
1•paulpauper•7m ago•0 comments

Trump: Permanently pause migration from all Third World Countries after shooting

https://www.cnbc.com/2025/11/28/trump-us-to-permanently-pause-migration-from-all-third-world-coun...
2•donsupreme•10m ago•0 comments

Gabe Newell Simulator

https://store.steampowered.com/app/407420/Gabe_Newell_Simulator/
2•doener•12m ago•0 comments

Show HN: Core – Constitutional AI achieving 70% autonomous coding

https://github.com/DariuszNewecki/CORE
1•d_newecki•12m ago•0 comments

OpenAI says dead teen violated TOS when he used ChatGPT to plan suicide

https://arstechnica.com/tech-policy/2025/11/openai-says-dead-teen-violated-tos-when-he-used-chatg...
3•Qem•14m ago•0 comments

GrapheneOS bails on OVHcloud over France's privacy stance

https://www.theregister.com/2025/11/28/grapheneos_ovhcloud/
6•Andromxda•17m ago•0 comments

Paul Ekman, Who Linked Facial Expressions to Universal Emotions, Dies at 91

https://www.nytimes.com/2025/11/26/science/paul-ekman-dead.html
1•bookofjoe•20m ago•1 comments

Is China winning the innovation race?

https://www.ft.com/content/3eccd40e-5ec0-43e8-a521-3b87e29e323b
3•artninja1988•24m ago•0 comments

Broadcasters Ensure You Comply with Best Practies to Prevent Cyberattacks [pdf]

https://docs.fcc.gov/public/attachments/DA-25-996A1.pdf
2•gnabgib•28m ago•0 comments

The Beautiful Prison: AI stuck in retro hardware asks: am I conscious?

https://thebeautifulprison.com/stories/the-beautiful-prison/
1•mjgardner•28m ago•1 comments

What's Next for AI? OpenAI's Łukasz Kaiser (Transformer Co-Author) [video]

https://www.youtube.com/watch?v=3K-R4yVjJfU
1•abrichr•31m ago•0 comments

What Are Blue-Green Deployments?

https://oneuptime.com/blog/post/2025-11-28-what-are-blue-green-deployments/view
4•ndhandala•34m ago•0 comments

FCC sounds alarm after emergency tones turned into potty-mouthed radio takeover

https://www.theregister.com/2025/11/27/fcc_radio_hijack/
4•Bender•35m ago•0 comments

Fabric Project

https://github.com/Fabric-Project/Fabric
4•brcmthrowaway•37m ago•0 comments

Wine 10.20 Released With VKD3D 1.18 Upgrade For Direct3D 12

https://www.phoronix.com/news/Wine-10.20-Released
4•Bender•37m ago•2 comments

AI Safety for Fleshy Humans

https://aisafety.dance/
4•sadeshmukh•40m ago•0 comments

What AI Won't Fix

https://www.blakeyoder.com/writing/what-ai-wont-fix
4•fictive_blake•42m ago•0 comments

Ozempic 2.0 is on the way, and it could be even more transformative

https://www.washingtonpost.com/health/2025/11/27/weight-loss-drugs-ozempic-pills-shots/
4•bookofjoe•44m ago•4 comments

I changed my address, and TransferWise in two days will empty my account

11•casenmgreen•45m ago•2 comments

MXroute are offering lifetime accounts for $75

https://mxroute.blackfriday/
2•AussieWog93•46m ago•2 comments

Confessions of a Software Developer: No More Self-Censorship

https://kerrick.blog/articles/2025/confessions-of-a-software-developer-no-more-self-censorship/
15•Kerrick•48m ago•0 comments

New Patches Work to Optimize Code Generation for Linux Context Switching

https://www.phoronix.com/news/Linux-CodeGen-Faster-Ctx-Switch
3•Bender•50m ago•0 comments

Show HN: I've built a Cursor alternative in browser. AI Coding Agent.

https://playcode.io
3•ianberdin•51m ago•0 comments

Scientists are baffled as mysterious halo of red light appears over Italian town

https://www.dailymail.co.uk/sciencetech/article-15332127/Mysterious-halo-red-light-appears.html
4•sipofwater•54m ago•2 comments

Show HN: NLCS – A Natural Language Constraint System for LLMs

https://github.com/chwmath-netizen/NLCS-S-Engine
1•chwmath•56m ago•1 comments

Show HN: Rhyme CTRL – Phoneme-Based Rhyme Detection with Whisper AI

https://github.com/MunamWasi/RHYME-CTRL
2•Munam•57m ago•0 comments

Giant of the Attic: On the Majesty of Alan Moore

https://www.metropolitanreview.org/p/giant-of-the-attic
2•CharlesW•1h ago•0 comments

Built autonomous AI with ethical consensus (SE45 Triad) Need bridge funding

1•Eidollona•1h ago•0 comments

A Tale of Two AI Failures: Debugging a Simple Bug with LLMs

https://bitmovin.com/blog/hackathon-debugging-ai-tools-llms/
3•slederer•1h ago•0 comments