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People Who Don't Lose Weight on Wegovy May Have Genetic Differences

https://www.scientificamerican.com/article/why-ozempic-and-wegovy-dont-cause-weight-loss-for-everyone/
3•paulpauper•1h ago

Comments

stavros•1h ago
I'm one of those people, but I have an absolutely bizarre response to the drug. I've tried to start it five times, and failed four.

I'll have one of two responses:

1. The drug works, and it completely eliminates food noise and the desire to eat unhealthy foods, but I'll get severe side effects (massive diarrhea, vomiting, burps that reek of rotten egg). I lose weight, but a lot of it because I can't keep anything down.

2. The drug doesn't work almost at all. I get minimal effects, and minimal side effects. This is where I am now, I've been consistently going up in dose (incrementally, so I don't trigger the side effects). I'm at 10mg now, and there's minimal effect.

Just mystifying.

Rope science, part 11 – practical syntax highlighting (2017)

https://xi-editor.io/docs/rope_science_11.html
1•todsacerdoti•28s ago•0 comments

Ask HN: White Label Chat Apps?

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https://apnews.com/article/hemp-thc-drinks-ban-law-8d77842cb250291a178db6f9d39f8b7e
3•petethomas•14m ago•0 comments

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https://www.ucl.ac.uk/news/2025/nov/air-pollution-may-reduce-health-benefits-exercise
2•hhs•18m ago•0 comments

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https://thelocal.to/investigating-scam-journalism-ai/
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https://www.rockefeller.edu/news/38658-how-the-brain-decides-what-to-remember/
1•hhs•30m ago•1 comments

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2•imjacobclark•30m ago•0 comments

Just Use Postgres for Everything

https://www.amazingcto.com/postgres-for-everything/
2•b-man•30m ago•0 comments

Rare Near-Equatorial Tropical Cyclone Senyar Hits Aceh, Indonesia

https://en.tempo.co/read/2068942/tropical-cyclone-senyar-makes-rare-landfall-in-aceh
1•terryds•31m ago•0 comments

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https://github.com/JacobHuang91/prompt-refiner
1•xinghaohuang•39m ago•1 comments

GreyNoise IP Check

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Evolution Strategies at the Hyperscale

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Nvidia ToolOrchestra – 8B model "manager" improves intelligence and efficiency

https://arxiv.org/abs/2511.21689
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Incidents: The Exceptional as Routine

https://surfingcomplexity.blog/2025/11/28/incidents-the-exceptional-as-routine/
2•azhenley•50m ago•0 comments

Kalshi hit as Nevada judge deems platform subject to gambling laws; will appeal

https://www.ft.com/content/2f07aed7-58b0-45d3-87d4-c3c883a616fa
4•hhs•51m ago•0 comments

Jetpack Navigation 3

https://android-developers.googleblog.com/2025/05/announcing-jetpack-navigation-3-for-compose.html
2•lairv•51m ago•0 comments

Shopify launched 3D Racing Game in the browser

https://www.shopify.com/ca/editions/summer2025/drive
2•terryds•1h ago•1 comments

Is AI Eating the World?

https://philippdubach.com/2025/11/23/is-ai-really-eating-the-world/
2•gmays•1h ago•0 comments

The Fatal Trap UBI Boosters Keep Falling Into

https://thereader.mitpress.mit.edu/the-fatal-trap-ubi-boosters-keep-falling-into/
3•haritha-j•1h ago•0 comments

When LLMs learn to take shortcuts, they become evil

https://www.economist.com/science-and-technology/2025/11/26/when-llms-learn-to-take-shortcuts-the...
2•etewiah•1h ago•1 comments

People Who Don't Lose Weight on Wegovy May Have Genetic Differences

https://www.scientificamerican.com/article/why-ozempic-and-wegovy-dont-cause-weight-loss-for-ever...
3•paulpauper•1h ago•1 comments

Design-a-Protein.com

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AI Music Sommelier and Gemini

https://dailyspotter.com/
2•levigrace•1h ago•2 comments

Structuring LLM outputs: best practices for legal prompt engineering (2024)

https://studio.netdocuments.com/post/structuring-llm-outputs
1•walterbell•1h ago•0 comments