fp.

Familial Alzheimer's mutation: Role of SORLA in release of neurotrophic exosomes

https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.70591

1•bookofjoe•20m ago•0 comments

Pirate Site Operator's Appeal Goes Bad, Court Extends Prison Term by 50%

https://torrentfreak.com/pirate-site-operators-appeal-goes-bad-court-extends-prison-term-by-50-25...

1•gslin•24m ago•0 comments

Kyoto and the Stories We Still Need to Tell About Fossil Fuel Obstruction

https://blog.ucs.org/delta-merner/kyoto-and-the-stories-we-still-need-to-tell-about-fossil-fuel-o...

1•cratermoon•29m ago•0 comments

When did cats become domesticated? New DNA evidence changes the story.

https://www.nationalgeographic.com/animals/article/when-did-cats-become-domesticated

1•donsupreme•30m ago•0 comments

SpecFive Strike: compact handheld Linux workstation

https://specfive.com/products/spec5-strike

3•nateb2022•34m ago•0 comments

Okeymeta

https://www.okeymeta.com.ng/

1•b16m•34m ago•0 comments

Ask HN: What Are You Working On?

3•dserban•39m ago•0 comments

Trump Cut Europe Out of Ukraine Talks

https://www.nytimes.com/2025/11/27/world/europe/europe-ukraine-trump.html

5•maxloh•42m ago•1 comments

Modern Developer Tools as Attack Surfaces: Lessons from Shai-Hulud

https://sitezwin.com/posts/2025-11-29-sha-hulud-the-second-coming-encouter/

2•meel-hd•55m ago•0 comments

Damage at Baikonur after Soyuz launch: Russia can't send people to space

https://unn.ua/en/news/damage-at-baikonur-after-soyuz-launch-russia-temporarily-lost-the-ability-...

2•cryptoz•57m ago•0 comments

Intelligence is too high-dimensional for any low-dimensional narrative

https://mathstodon.xyz/@tao/115620261936846090

3•gmays•59m ago•1 comments

20/80

https://blog.greg.technology/2025/11/27/2080.html

2•gregsadetsky•1h ago•0 comments

The Supreme Court Is About to Hear a Case That Could Rewrite Internet Access

https://slate.com/news-and-politics/2025/11/supreme-court-sony-cox-copryight-internet-case.html

8•anthonyu•1h ago•2 comments

Show HN: Generate Sheet Music Using AI (Scribe)

https://scribe.rifflabs.io

2•hwittenborn•1h ago•0 comments

Tesla looks to reset strategy amid sluggish India sales

https://www.bbc.com/news/articles/cdrn00pn1m7o

2•breve•1h ago•0 comments

Chumbox (Advertising)

https://en.wikipedia.org/wiki/Chumbox

3•rickcarlino•1h ago•0 comments

Large Type Pieces.txt

https://github.com/PhMajerus/Documents/blob/main/HowTos/HowTo%20Large%20Type%20Pieces.txt

2•cardamomo•1h ago•0 comments

Every mathematician has only a few tricks

https://mathoverflow.net/questions/363119/every-mathematician-has-only-a-few-tricks

5•nill0•1h ago•0 comments

Plotting a Northrop B2 Spirit

https://youtu.be/TSQWZF4zdN4

2•russelltaylor05•1h ago•0 comments

The Risky Movement to Make America Nuclear Again

https://nuclear-news.net/2025/11/04/1-a-the-risky-movement-to-make-america-nuclear-again/

2•pmoriarty•1h ago•0 comments

Rocketwerkz CEO says frameworks, not engines, are the future of game development

https://www.gamedeveloper.com/programming/rocketwerkz-ceo-predicts-frameworks-not-engines-will-be...

5•jibe•1h ago•0 comments

Mongolian Script

https://en.wikipedia.org/wiki/Mongolian_script

3•Razengan•1h ago•0 comments

The Impossible Prompt That's Easy for Humans

https://teodordyakov.github.io/the-impossible-promt/

2•ssdsa•1h ago•2 comments

Why GitHub's War on Toasts Is Bad News for Accessibility

https://medium.com/offmessageorg/why-githubs-war-on-toasts-is-bad-news-for-accessibility-a88ddbad...

3•bochoh•1h ago•0 comments

Beijing's prison silences Chinese journalist and lawyer of Covid19 in Wuhan fame

https://www.bushcenter.org/publications/the-struggle-for-freedom-beijings-revolving-prison-doors-...

4•737min•1h ago•0 comments

Show HN: MCP for finding the better NPM dependencies

https://web-production-0200a.up.railway.app

1•jsafaiyeh•1h ago•0 comments

Show HN: Native macOS timeout (Rust) – handles system sleep, no coreutils

https://github.com/denispol/darwin-timeout

1•denispol•1h ago•0 comments

Show HN: TimeProof – Timelapse your computer based workday! (MacOS)

https://apps.apple.com/us/app/timeproof/id6751671026?mt=12

1•Viper117•1h ago•1 comments

Infosys co-founder once again calls for longer than 70-hour weeks – and no, he's

https://www.techradar.com/pro/infosys-co-founder-once-again-calls-for-longer-than-70-hour-weeks-a...

13•sys_64738•1h ago•2 comments

Tesla struggles to course correct from sales skid

https://www.reuters.com/business/autos-transportation/tesla-struggles-course-correct-sales-skid-2...

6•breve•1h ago•1 comments