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Nanoparticles that enhance mRNA delivery could reduce vaccine dosage and costs

https://phys.org/news/2025-11-nanoparticles-mrna-delivery-vaccine-dosage.html
1•PaulHoule•1h ago

My Search for the Kaleidacousticon [pdf]

https://midnightsledding.net/documents/Kaleidacousticon.pdf
1•hlynurd•15s ago•0 comments

Show HN: Zero – Burner Video Links for Online Dating (WebRTC)

https://meet-zero.co
1•arush436•1m ago•0 comments

Show HN: I made a fighting game where Elon and Zuck can settle it

https://www.siliconfighter.com
1•juanfiguera•2m ago•0 comments

40 Year Heist

https://40yearheist.com/
4•bayeslaw•12m ago•0 comments

Strangler Fig Pattern – How to modernize a legacy stack without a full rewrite

https://learn.microsoft.com/en-us/azure/architecture/patterns/strangler-fig
1•thunderbong•12m ago•0 comments

Show HN: Hackerest – Real-time penetration testing, built by security engineers

https://hackerest.com
2•mcisternino•14m ago•0 comments

Show HN: LangGraph profiling – 737x Faster Checkpoints via Rust (PyO3)

https://github.com/neul-labs/fast-langgraph
1•ticktockten•15m ago•0 comments

Let's Decrypt dot org redirects to the NSA

https://letsdecrypt.org
1•martinclayton•16m ago•1 comments

Ask HN: Is a JVM/CDP based browser agent stack fundamentally a bad idea?

1•galaxyeye•17m ago•0 comments

'Factory' in cells found to prevent insulin abnormalities

https://www.japantimes.co.jp/news/2025/11/12/japan/science-health/cell-factory-insulin/
2•PaulHoule•19m ago•0 comments

How to Get Audio Clip from an Audio File in Mac with Quick Time Player [video]

https://www.youtube.com/watch?v=J3dXs0Yb7Yg
1•techwrath11•19m ago•0 comments

How to Copy Paste in Mac from One Folder to Another [video]

https://www.youtube.com/watch?v=34_afpe9PH0
1•techwrath11•20m ago•0 comments

Show HN: SafeShare – Clean up tracking parameters (UTM, fbclid, gclid)

https://j-ai-71.github.io/Supersystem/app.html
1•safeshare•21m ago•0 comments

War Department Unleashes AI on New GenAI.mil Platform

https://www.war.gov/News/Releases/Release/Article/4354916/the-war-department-unleashes-ai-on-new-...
1•michaelsbradley•22m ago•0 comments

Show HN: SolarStorm – Visualising space weather effects on the power grid

https://solarstorm.space/
5•petargyurov•22m ago•0 comments

Show HN: Tracktions – Bringing institutional trading structure to retail traders

https://tracktions.com/
1•Tracktions•23m ago•1 comments

In your first two weeks on a new team

https://natashajaffe.substack.com/p/in-your-first-two-weeks-on-a-new
1•natasha_jaffe•23m ago•1 comments

Factor 0.101 Now Available

https://re.factorcode.org/2025/12/factor-0-101-now-available.html
1•birdculture•24m ago•0 comments

Inside Fire: Poetry for the Intellect [pdf]

https://theboina.org/titles/Inside%20Fire.pdf
1•control-h•25m ago•0 comments

Memory leak regression testing with V8/Node.js

https://joyeecheung.github.io/blog/2024/03/17/memory-leak-testing-v8-node-js-1/
1•todsacerdoti•26m ago•0 comments

Velocipedia

https://www.gianlucagimini.it/portfolio-item/velocipedia/
1•lloeki•29m ago•0 comments

IETF draft and Rust POC: NTP for Bitcoin price (no oracles)

https://github.com/CryptoPriceProtocol/BitCoinPriceProtocol
1•usacoder•32m ago•0 comments

UK Parliament e-petition Debate: Do not introduce Digital ID cards

https://hansard.parliament.uk/Commons/2025-12-08/debates/9E01F17C-557A-4D02-8A93-B573721B8B20/a
2•mapleoin•32m ago•0 comments

Former Mozaic Payments CEO arrested, charged with defrauding PE investor

https://www.reuters.com/legal/government/tech-startup-ceo-defrauded-private-equity-firm-out-20-mi...
1•ilamont•33m ago•0 comments

Show HN: Peaktech PSU Control from Emacs

https://github.com/bwachter/peaktech-psu
1•finaard•35m ago•0 comments

BJH OS – Free Open Source Browser OS for Windows, Mac, Linux, Android, iPhone

https://bjhos.unaux.com
1•Haris18•36m ago•2 comments

Fix for Slow Open and Save Dialog on macOS

https://rknight.me/blog/fix-for-slow-open-and-save-dialog-macos/
2•rknightuk•38m ago•0 comments

Steam Workshop Downloader – Fast and Free Tool

https://steamworkshopdownloader.net
2•quchao•41m ago•3 comments

Show HN: A really really simple text-based budget app

https://github.com/alexandreprl/budget-as-a-text
1•Eagle64•42m ago•0 comments

OpenAI, Anthropic, and Block donate agent tools to new 'Agentic AI Foundation'

https://techoreon.com/openai-anthropic-block-agentic-ai-foundation-linux/
1•GeorgeWoff25•46m ago•0 comments