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Scientists Look to Ancient Microbes to Discover the Antibiotics of the Future

https://www.calpoly.edu/news/cal-poly-scientists-look-ancient-microbes-discover-antibiotics-future
3•PaulHoule•22h ago

Comments

DaveZale•21h ago
they need a good lc/ms chemist

Who falls for misinformation?: Epistemic beliefs and political identity

https://liu.diva-portal.org/smash/record.jsf?pid=diva2%25253A2001550&dswid=5902
1•bikenaga•1m ago•0 comments

The Great Al Debate Who Is Right? [video]

https://www.youtube.com/watch?v=MXFEf9xSKAo
1•avonmach•1m ago•0 comments

CEO of South Korean online retail giant Coupang resigns over data breach

https://www.cnbc.com/2025/12/10/ceo-of-south-korean-online-retail-giant-coupang-resigns-over-data...
1•mgh2•1m ago•0 comments

HN time capsule hn comments analyzed by AI with hindsights 10yr later

https://karpathy.ai/hncapsule/
1•rmnwski•3m ago•0 comments

Humans Near top of list of monogamous mammals

https://www.theguardian.com/science/2025/dec/10/humans-rank-among-leading-monogamous-mammals-stud...
1•zafka•3m ago•0 comments

Reflections on my first year writing full time

https://www.henrikkarlsson.xyz/p/2025
1•jger15•3m ago•0 comments

Terraform Provider Registry Outage

https://status.hashicorp.com
1•deathanatos•5m ago•1 comments

Show HN: CIX – deterministic indexing for stable LLM sessions (10-second PoC)

https://github.com/VikingFlow/continuous-index
1•VikingFlowAI•6m ago•0 comments

AI as the Great Democratizer

https://theautomatedoperator.substack.com/p/ai-as-the-great-democratizer
1•idopmstuff•6m ago•0 comments

Fedora introduces LLM that suggests using apt to solve the issue

https://fedoramagazine.org/find-out-how-your-fedora-system-really-feels-with-the-linux-mcp-server/
1•butz•6m ago•0 comments

HTML Changes in ePub

https://htmhell.dev/adventcalendar/2025/11/
1•soheilpro•7m ago•0 comments

Show HN: VICW – Virtual Infinite Context Window

https://github.com/elevend0g/vicw
1•elevend0g•7m ago•0 comments

Cosmic Desktop is a fantastic first draft [video]

https://www.youtube.com/watch?v=ob-Y77kuVwM
1•todsacerdoti•10m ago•0 comments

New in Llama.cpp: Model Management

https://huggingface.co/blog/ggml-org/model-management-in-llamacpp
1•geerlingguy•11m ago•0 comments

Why Your RAG Costs $2,400/Month (and How We Cut It by 73%)

2•helain•13m ago•0 comments

Show HN: I built a WebMIDI sequencer to control my hardware synths

https://www.simplychris.ai/droplets
1•simplychris•13m ago•0 comments

What you should know about constraints in PostgreSQL

https://xata.io/blog/constraints-in-postgres
3•tudorg•14m ago•0 comments

The Agents Shared Cognition Protocol (ASCP)

https://github.com/Reframe-Technologies/ascp-draft-specs
1•talljeff68•14m ago•1 comments

Rivian Autonomy and AI Day

https://stories.rivian.com/rivian-autonomy-ai-day
1•songeater•15m ago•0 comments

DRM-Free Kindle EBooks Will Be Downloadable in ePub and PDF Formats Soon

https://blog.the-ebook-reader.com/2025/12/11/drm-free-kindle-ebooks-will-be-downloadable-in-epub-...
1•CrypticShift•16m ago•0 comments

Show HN: A daily logic puzzle game based on parity constraints

1•greyisodd•16m ago•0 comments

Why Text in Vampire Survivors Used to Look Weird

https://jslegenddev.substack.com/p/vampire-survivors-text-weird
1•JSLegendDev•17m ago•0 comments

Show HN: Remixify – Turn any Spotify playlist into a remix playlist

1•kwakubiney•17m ago•0 comments

Unity vs. Unreal – Which Engine Fits Your Next Game?

https://www.slavnastudio.com/blog/unity-vs-unreal-engine-a-comprehensive-comparison/
2•SofiaK•17m ago•1 comments

Fwknop: Single Packet Authorization > Port Knocking

https://www.cipherdyne.org/fwknop/
1•l2dy•18m ago•0 comments

Backpressure in Streaming Systems

https://risingwave.com/blog/backpressure-in-streaming-systems/
2•AnneWodell•24m ago•0 comments

Show HN: DriftOS – Stop dumping chat history into LLM context windows

https://www.driftos.dev/
2•scott_waddell•24m ago•1 comments

Show HN: Inkling – Local semantic search to make finding your documents easier

https://tkoduru.tech/inkling-app/
1•aerot•27m ago•0 comments

R1: A Foundational Model for Small Molecule Drug Discovery

https://rhizomeresearch.ai/blog/announcing-r1
1•davepeck•27m ago•0 comments

Five Genetic Factors Link Depression, Anxiety, Schizophrenia

https://www.technologynetworks.com/genomics/news/five-genetic-clusters-explain-over-half-of-all-p...
1•gmays•28m ago•0 comments