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Will blockbuster obesity drugs revolutionize addiction treatment?

https://www.nature.com/articles/d41586-025-03911-x
4•qnleigh•5h ago

Comments

tom86150•4h ago
Addict reporting in. It is the wrong approach to take medication again to treat a behavioral problem. Every good therapist advises against it. In the case of addiction, behavior, living conditions, and environment must change. I moved away and, of course, stopped going to bars or concerts. You have to pay this price until you find a meaningful activity to replace the time you spent consuming. You can no longer be friends with users, and if your job was bad, you have to find another one. These drugs are also no substitute for withdrawal treatment, where you learn how to behave in risky situations, e.g., when you are pressured to drink a beer. You also have to expect relapses and accept that addiction is not curable, you can only stop it. However, many people can still live well sober. Addiction is like driving on a well-travelled road. With the substance, everything is smooth, normal, and you get where you want to go. The new, sober path is bumpy and it takes time for the road to become just as well-travelled. Normally, the craving disappears after about a year, and then you can say that the worst is over. In the meantime, you have changed something. I found a job where I have to drive sober, which keeps me from using very well. I also have an expensive, classic scooter, which I have to bring home sober, and I meet up with people and have social contact again It might be a comfy way to delegate problems you still have to medication and doctors, the most work you have to do yourself.

Show HN: A local-first memory store for LLM agents (SQLite)

https://github.com/CaviraOSS/OpenMemory
1•nullure•2m ago•0 comments

'Holy crap. The end of me: ex-Google CEO Eric Schmidt on AI doing coding jobs

https://timesofindia.indiatimes.com/technology/tech-news/holy-crap-the-end-of-me-says-ex-google-c...
1•ashishgupta2209•3m ago•0 comments

My 2025 Stack – Grok Code Fast, Cline, Self-Hosting, and Barber Beats

https://mateo-siam.com/blog/2025-best-of-the-year/
1•Mateleo•8m ago•1 comments

Hetz – Make Website Footers / tables / navigation menus online tool

https://hetz.ct.ws/
1•aminekhd•11m ago•0 comments

Samsung to halt SATA SSD production

https://www.notebookcheck.net/Samsung-to-halt-SATA-SSD-production-leaker-warns-of-up-to-18-months...
1•turrini•12m ago•0 comments

Gunmen kill 9 people at Sydney's Bondi Beach

https://apnews.com/article/australia-shooting-sydney-bondi-beach-31f711f09f677d0f88091ece25f651c1
2•wslh•12m ago•0 comments

Lightweight Rust Alternative CDK to Airbyte

https://github.com/kubent-solidafy/solidafy-cdk
1•kubent•14m ago•0 comments

Ask HN: How do I navigate horror of requirement gathering in product management?

1•souravpradhan•16m ago•1 comments

Show HN: Sub-agents for Cursor via MCP (isolated context, no worktrees)

https://github.com/shinpr/sub-agents-mcp
1•shinpr•18m ago•1 comments

Show HN: LudvigEditor – A lightweight Python alternative to Electron editors

https://github.com/Ludvig2457Ultra/LudvigEditor
2•ludvig2457•20m ago•1 comments

How redefining disability/special needs has changed education

https://www.ft.com/content/8252a3bf-f3a5-4cbf-baeb-237a8d5b022b
1•walthamstow•23m ago•0 comments

Adventure can be disastrous: digital nomad families 'worldschooling' their kids

https://www.theguardian.com/lifeandstyle/2025/dec/14/the-adventure-can-turn-into-a-disaster-the-d...
2•Geekette•36m ago•0 comments

Show HN: CryptoGig – A Marketplace for Freelancers Paid in Crypto

https://cryptogig.com/
1•annakoren•50m ago•0 comments

10 People killed in Bondi Beach shooting

https://www.abc.net.au/news/2025-12-14/active-shooter-bondi-beach-sydney-nsw/106141580
8•BLKNSLVR•53m ago•0 comments

DoomScroll – Browse, preview, and play user-made Doom WADs in the browser

https://doomscroll.cx
1•jsheard•54m ago•0 comments

Git Will Make Sense After This [video]

https://www.youtube.com/watch?v=Ala6PHlYjmw
1•matthew16550•55m ago•0 comments

Show HN: cvfitr.com – An AI Job Application tailoring site

https://cvfitr.com
2•iamdavidmt•1h ago•0 comments

Dogalog: A realtime Prolog-based livecoding music environment

https://github.com/danja/dogalog
2•triska•1h ago•1 comments

University life: From 50 years ago to now (2019)

https://www.timeshighereducation.com/student/blogs/university-life-50-years-ago-now
4•zeristor•1h ago•0 comments

Shai-Hulud compromised a dev machine and raided GitHub org access: a post-mortem

https://trigger.dev/blog/shai-hulud-postmortem
4•nkko•1h ago•1 comments

Scale Test-Time Compute with Parallel Coordinated Reasoning [pdf]

https://github.com/stepfun-ai/PaCoRe/blob/main/pacore_report.pdf
1•nkko•1h ago•0 comments

Internet in the Age of Agents

https://thinkininpublic.substack.com/p/internet-in-the-age-of-agents
1•sujayk_33•1h ago•0 comments

Willison on Merchant's "Copywriters reveal how AI has decimated their industry"

https://simonwillison.net/2025/Dec/14/copywriters-reveal-how-ai-has-decimated-their-industry/
4•planckscnst•1h ago•1 comments

How to install a Toolchain for clang on phones without root access (2024, 2025)

https://xdaforums.com/t/guide-how-to-install-a-toolchain-for-clang-on-phones-without-root-access....
1•sipofwater•1h ago•2 comments

How the invention of buttons led to simplicity and to planned obsolescence

https://mikajovicic.com/writing/button-invention-made-interface-simplicity-possible/
2•violinar•1h ago•0 comments

Vanessa et S., magnifique dominatrice (13)

https://dominamag.com/suprematie-feminine/vanessa-et-s-magnifique-dominatrice-13/
1•ssoumi•1h ago•0 comments

Why We Age

https://onlinelibrary.wiley.com/doi/10.1002/brv.70109
2•XzetaU8•1h ago•0 comments

We Sent Our CEO to Dubai's Supercar Junkyards [video]

https://www.youtube.com/watch?v=IrGCv3sZXAQ
1•teleforce•1h ago•0 comments

An open-source energy and latency profiler for LLMs: ELANA

https://arxiv.org/abs/2512.09946
1•nkko•1h ago•0 comments

Total Internet Shutdowns per Year

https://public.tableau.com/app/profile/zach.rosson/viz/STOP_v2/Dashboard1
3•vivzkestrel•1h ago•1 comments