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With FDA approval of Wegovy pill, new era of oral GLP-1 weight loss drugs begins

https://www.cnn.com/2025/12/22/health/wegovy-pill-glp1-weight-loss-drugs
6•andsoitis•2h ago

The Duodecimal Bulletin, Vol. 55, No. 1, Year 1209 [pdf]

https://dozenal.org/drupal/sites_bck/default/files/DuodecimalBulletinIssue551.pdf
1•susam•33s ago•0 comments

NYC Spends $200 Million on Cell Service for School Chromebooks

https://nysfocus.com/2025/12/22/eric-adams-school-chromebooks-contract
2•h2si•2m ago•0 comments

I Stopped Reading and Embraced Audiobooks

https://www.nytimes.com/2025/12/21/books/review/audiobooks-reading-listening-habits.html
2•lxm•3m ago•0 comments

Administration suspends 5 wind projects off East Coast, cites security concerns

https://apnews.com/article/trump-offshore-wind-energy-climate-c0ac1e447c93126327f1922327921aa0
2•JKCalhoun•5m ago•1 comments

I Died on DMT

https://rebeccadai.substack.com/p/i-died-on-dmt
3•randomparticlez•8m ago•0 comments

Running Claude Code from my phone via SSH with Tailscale and tmux

https://www.qu8n.com/posts/running-claude-code-from-my-phone
3•quanwinn•9m ago•0 comments

In stock on Framework Desktop and updates on the industry-wide silicon crunch

https://community.frame.work/t/in-stock-on-framework-desktop-and-updates-on-the-industry-wide-sil...
2•nateb2022•13m ago•0 comments

Data 2025: The year in review with Mike Stonebraker and Andy Pavlo

https://www.dbos.dev/webcast-2025-in-review-with-mike-stonebraker-and-andy-pavlo
2•teleforce•15m ago•0 comments

Antimeme Antichrist

https://www.johnnychang.com/antimeme/
3•zcase•17m ago•1 comments

FDA Approves Pill Version of Wegovy

https://www.wired.com/story/fda-approves-pill-version-of-wegovy/
3•stein1946•17m ago•1 comments

Release Trains Aren't About Releases

https://cameronwestland.com/release-trains-arent-about-releases/
2•camwest•18m ago•1 comments

Wozmonc64.bas

https://github.com/gabrielsroka/gabrielsroka.github.io/blob/master/wozmon/wozmonc64.bas
2•gabrielsroka•19m ago•1 comments

State of the Geomagnetic Field, December 2025 (PDF 19 pages)

https://www.ncei.noaa.gov/sites/default/files/2025-12/WMM%20SoGF%20Dec2025%20508.pdf
2•defrost•23m ago•0 comments

A House Ahead of Its Time (2024)

https://www.nist.gov/feature-stories/house-ahead-its-time
2•1659447091•26m ago•0 comments

Exposing a $10B Fraudulent Debt Relief Industry [video]

https://www.youtube.com/watch?v=hBNWInRS6hM
3•fortran77•29m ago•0 comments

President Trump Announces New Trump Class Battleship

https://www.navy.mil/Press-Office/Press-Releases/display-pressreleases/Article/4366856/president-...
4•duxup•30m ago•2 comments

Show HN: StringTune-3D – Control Three.js scenes via CSS variables

https://github.com/penev-palemiya/StringTune-3D
2•penev_tech•39m ago•0 comments

We removed 80% of our agent's tools

https://vercel.com/blog/we-removed-80-percent-of-our-agents-tools
2•forks•41m ago•0 comments

Jim Beam halts production at main distillery for a year

https://www.bbc.com/news/articles/cy5gv5z24n2o
4•geox•46m ago•0 comments

Snitch – a friendly netstat alternative for humans

https://github.com/karol-broda/snitch
2•karol-broda•46m ago•0 comments

Grok Collections API

https://x.ai/news/grok-collections-api
2•lmariscal•48m ago•1 comments

San Francisco power won't be fully restored until Tuesday, PG&E says

https://www.sfgate.com/bayarea/article/san-francisco-power-pge-outage-21255221.php
2•bryan0•52m ago•0 comments

Colorado Windstorm Causes 4.8 Microsecond Glitch in Official US Time

https://gizmodo.com/colorado-windstorm-causes-4-8-microsecond-glitch-in-official-u-s-time-2000702524
2•Stratoscope•52m ago•1 comments

Salisbury Steak is super weird

https://www.youtube.com/watch?v=d9z8DK_VWKs
2•bane•52m ago•0 comments

Document search using Claude and Inverted Index

https://annanay.dev/claude-inverted-index-search/
2•annanay•54m ago•0 comments

Aspartame study suggests that current guidelines should be re-examined

https://www.sciencedirect.com/science/article/pii/S0753332225010856
2•shaggie76•55m ago•0 comments

Trump Administration Declares Foreign-Made Drones a Security Threat

https://www.nytimes.com/2025/12/22/us/dji-drones-china-barred-us.html
3•Sherveen•57m ago•2 comments

Regenerative Software

https://aicoding.leaflet.pub/3majnyfydzs2y
3•andsoitis•1h ago•0 comments

Architecture Patterns: Caching (2022)

https://kislayverma.com/software-architecture/architecture-patterns-caching-part-2/
2•sneakerblack•1h ago•0 comments

Instacart halts AI testing program that raised costs for some shoppers

https://www.washingtonpost.com/business/2025/12/22/instacart-price-testing-program/
2•bookofjoe•1h ago•1 comments