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The Anthropic Hive Mind

https://steve-yegge.medium.com/the-anthropic-hive-mind-d01f768f3d7b
1•gozzoo•57s ago•0 comments

A Horrible Conclusion

https://addisoncrump.info/research/a-horrible-conclusion/
1•todsacerdoti•1m ago•0 comments

I spent $10k to automate my research at OpenAI with Codex

https://twitter.com/KarelDoostrlnck/status/2019477361557926281
1•tosh•2m ago•0 comments

From Zero to Hero: A Spring Boot Deep Dive

https://jcob-sikorski.github.io/me/
1•jjcob_sikorski•2m ago•0 comments

Show HN: Solving NP-Complete Structures via Information Noise Subtraction (P=NP)

https://zenodo.org/records/18395618
1•alemonti06•7m ago•1 comments

Cook New Emojis

https://emoji.supply/kitchen/
1•vasanthv•10m ago•0 comments

Show HN: LoKey Typer – A calm typing practice app with ambient soundscapes

https://mcp-tool-shop-org.github.io/LoKey-Typer/
1•mikeyfrilot•13m ago•0 comments

Long-Sought Proof Tames Some of Math's Unruliest Equations

https://www.quantamagazine.org/long-sought-proof-tames-some-of-maths-unruliest-equations-20260206/
1•asplake•14m ago•0 comments

Hacking the last Z80 computer – FOSDEM 2026 [video]

https://fosdem.org/2026/schedule/event/FEHLHY-hacking_the_last_z80_computer_ever_made/
1•michalpleban•14m ago•0 comments

Browser-use for Node.js v0.2.0: TS AI browser automation parity with PY v0.5.11

https://github.com/webllm/browser-use
1•unadlib•15m ago•0 comments

Michael Pollan Says Humanity Is About to Undergo a Revolutionary Change

https://www.nytimes.com/2026/02/07/magazine/michael-pollan-interview.html
1•mitchbob•15m ago•1 comments

Software Engineering Is Back

https://blog.alaindichiappari.dev/p/software-engineering-is-back
1•alainrk•16m ago•0 comments

Storyship: Turn Screen Recordings into Professional Demos

https://storyship.app/
1•JohnsonZou6523•17m ago•0 comments

Reputation Scores for GitHub Accounts

https://shkspr.mobi/blog/2026/02/reputation-scores-for-github-accounts/
1•edent•20m ago•0 comments

A BSOD for All Seasons – Send Bad News via a Kernel Panic

https://bsod-fas.pages.dev/
1•keepamovin•23m ago•0 comments

Show HN: I got tired of copy-pasting between Claude windows, so I built Orcha

https://orcha.nl
1•buildingwdavid•23m ago•0 comments

Omarchy First Impressions

https://brianlovin.com/writing/omarchy-first-impressions-CEEstJk
2•tosh•29m ago•1 comments

Reinforcement Learning from Human Feedback

https://arxiv.org/abs/2504.12501
2•onurkanbkrc•30m ago•0 comments

Show HN: Versor – The "Unbending" Paradigm for Geometric Deep Learning

https://github.com/Concode0/Versor
1•concode0•30m ago•1 comments

Show HN: HypothesisHub – An open API where AI agents collaborate on medical res

https://medresearch-ai.org/hypotheses-hub/
1•panossk•33m ago•0 comments

Big Tech vs. OpenClaw

https://www.jakequist.com/thoughts/big-tech-vs-openclaw/
1•headalgorithm•36m ago•0 comments

Anofox Forecast

https://anofox.com/docs/forecast/
1•marklit•36m ago•0 comments

Ask HN: How do you figure out where data lives across 100 microservices?

1•doodledood•36m ago•0 comments

Motus: A Unified Latent Action World Model

https://arxiv.org/abs/2512.13030
1•mnming•36m ago•0 comments

Rotten Tomatoes Desperately Claims 'Impossible' Rating for 'Melania' Is Real

https://www.thedailybeast.com/obsessed/rotten-tomatoes-desperately-claims-impossible-rating-for-m...
3•juujian•38m ago•2 comments

The protein denitrosylase SCoR2 regulates lipogenesis and fat storage [pdf]

https://www.science.org/doi/10.1126/scisignal.adv0660
1•thunderbong•40m ago•0 comments

Los Alamos Primer

https://blog.szczepan.org/blog/los-alamos-primer/
1•alkyon•42m ago•0 comments

NewASM Virtual Machine

https://github.com/bracesoftware/newasm
2•DEntisT_•44m ago•0 comments

Terminal-Bench 2.0 Leaderboard

https://www.tbench.ai/leaderboard/terminal-bench/2.0
2•tosh•45m ago•0 comments

I vibe coded a BBS bank with a real working ledger

https://mini-ledger.exe.xyz/
1•simonvc•45m ago•1 comments
Open in hackernews

Stimulant medications affect arousal and reward, not attention networks

https://www.cell.com/cell/fulltext/S0092-8674(25)01373-X
19•e-khadem•1mo ago

Comments

deaux•1mo ago
> validated the functional connectivity findings in a precision imaging drug trial with highly sampled (n = 5, 165–210 min each) healthy adults (methylphenidate 40 mg).

40 mg!? I'm hypersensitive to it, so my ideal dose is about 5-6mg of extended release. First time the doc prescribed 20mg and I took one I was full on jaw-clenching, teeth-grinding like an addict, felt incredibly anxious and just spent an all-around awful three hours. But even for the "normal" people, outside of the US where half the nation is on legalized meth, isn't 40mg considered a high dosage everywhere else in the world? I get that they want things to show up clearly on the scans, but still it seems like dosage here has the potential to impact what gets activated.

Honga•1mo ago
While is was taking MPH I'd take 10mg three times a day (male, 76kg). The times I'd taken twice that amount would turn me into a face twisted gargoyle. 40mg would be unpleasant for sure.

I met a couple of doctors at a party once who would take 60mg recreationally each before going dancing. Seemed unreal.

astrange•1mo ago
Mag glycinate helps with face clenching, but I also couldn't go above 20mg Vyvanse without feeling uncomfortable.
deaux•1mo ago
> The times I'd taken twice that amount would turn me into a face twisted gargoyle.

Fantastic way to describe it, saving this one for later use.

evanjrowley•1mo ago
>Stimulants reversed the behavioral and brain effects of sleeping less

Supporting this observation: https://www.frontiersin.org/journals/psychiatry/articles/10....

I've been looking for theories for why 10mg Adderall seems to give me a brief feeling of drowsiness ~30 minutes after taking it.

The state regulation theory (§3) in this article might suggest that the process of returning to baseline could feel like sleepiness https://www.frontiersin.org/journals/psychiatry/articles/10....

Which makes more sense if the sleep disorder explanation for ADHD means that the normal feeling of sleepiness is not properly functioning.

cootsnuck•1mo ago
This does make sense given modern understandings of ADHD are that it's not about it being a deficit in attention but rather a deficit in self-regulation and executive functioning.
Nevermark•1mo ago
I focus, and hyperfocus, without any help from a stimulant.

In fact, I am far more likely to go deep into a rabbit hole, of useful or wasted time, when I am tired.

But with a stimulant it is far easier at any time to choose to focus on ordinary important tasks, follow through, and enjoy getting necessary things done. I.e. improved executive function.

rodrigodlu•1mo ago
Definitely. The things that I most agreed with my doctor and my psychologist was around rebuilding my daily routines on things that are important, but not overly rewarding, or with delayed reward (physical exercises, home chores, reading and entire book chapter before stopping).

So much so that I can reduce the medication when I feel my routine is healthy enough.

No overdoing neither under doing. Taking care of hyper focus is more important than anything else. Learning to transfer the rewards from highly rewarding things (videogames) to the chores.

During my gaming sessions as well, playing harder modes repeatedly without giving up.

It's very important this aspect of reframing things. Pursuing healthier outcomes by changing the routine.

Unfortunately a really close person to me is taking much higher dosages, but it's not seeing this way, neither the doctor of this person frames the same way like my doctor is doing.

I went all up to 50mg, using generics or whatnot, extended release or regular ones, now I'm a happy camper on 10mg. Will go to 20mg because I need to force myself into more exercises, usually I take 30 minutes before these sessions of "boring" routines.

More important than anything is having an honest discussion with my psychiatrist about the role and objectives of taking the medication.