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Show HN: WP Float – Archive WordPress blogs to free static hosting

https://wpfloat.netlify.app/
1•zizoulegrande•1m ago•0 comments

Show HN: I Hacked My Family's Meal Planning with an App

https://mealjar.app
1•melvinzammit•1m ago•0 comments

Sony BMG copy protection rootkit scandal

https://en.wikipedia.org/wiki/Sony_BMG_copy_protection_rootkit_scandal
1•basilikum•4m ago•0 comments

The Future of Systems

https://novlabs.ai/mission/
2•tekbog•5m ago•1 comments

NASA now allowing astronauts to bring their smartphones on space missions

https://twitter.com/NASAAdmin/status/2019259382962307393
2•gbugniot•9m ago•0 comments

Claude Code Is the Inflection Point

https://newsletter.semianalysis.com/p/claude-code-is-the-inflection-point
2•throwaw12•11m ago•1 comments

Show HN: MicroClaw – Agentic AI Assistant for Telegram, Built in Rust

https://github.com/microclaw/microclaw
1•everettjf•11m ago•2 comments

Show HN: Omni-BLAS – 4x faster matrix multiplication via Monte Carlo sampling

https://github.com/AleatorAI/OMNI-BLAS
1•LowSpecEng•12m ago•1 comments

The AI-Ready Software Developer: Conclusion – Same Game, Different Dice

https://codemanship.wordpress.com/2026/01/05/the-ai-ready-software-developer-conclusion-same-game...
1•lifeisstillgood•14m ago•0 comments

AI Agent Automates Google Stock Analysis from Financial Reports

https://pardusai.org/view/54c6646b9e273bbe103b76256a91a7f30da624062a8a6eeb16febfe403efd078
1•JasonHEIN•17m ago•0 comments

Voxtral Realtime 4B Pure C Implementation

https://github.com/antirez/voxtral.c
2•andreabat•19m ago•0 comments

I Was Trapped in Chinese Mafia Crypto Slavery [video]

https://www.youtube.com/watch?v=zOcNaWmmn0A
1•mgh2•25m ago•0 comments

U.S. CBP Reported Employee Arrests (FY2020 – FYTD)

https://www.cbp.gov/newsroom/stats/reported-employee-arrests
1•ludicrousdispla•27m ago•0 comments

Show HN: I built a free UCP checker – see if AI agents can find your store

https://ucphub.ai/ucp-store-check/
2•vladeta•32m ago•1 comments

Show HN: SVGV – A Real-Time Vector Video Format for Budget Hardware

https://github.com/thealidev/VectorVision-SVGV
1•thealidev•34m ago•0 comments

Study of 150 developers shows AI generated code no harder to maintain long term

https://www.youtube.com/watch?v=b9EbCb5A408
1•lifeisstillgood•34m ago•0 comments

Spotify now requires premium accounts for developer mode API access

https://www.neowin.net/news/spotify-now-requires-premium-accounts-for-developer-mode-api-access/
1•bundie•37m ago•0 comments

When Albert Einstein Moved to Princeton

https://twitter.com/Math_files/status/2020017485815456224
1•keepamovin•38m ago•0 comments

Agents.md as a Dark Signal

https://joshmock.com/post/2026-agents-md-as-a-dark-signal/
2•birdculture•40m ago•0 comments

System time, clocks, and their syncing in macOS

https://eclecticlight.co/2025/05/21/system-time-clocks-and-their-syncing-in-macos/
1•fanf2•42m ago•0 comments

McCLIM and 7GUIs – Part 1: The Counter

https://turtleware.eu/posts/McCLIM-and-7GUIs---Part-1-The-Counter.html
2•ramenbytes•44m ago•0 comments

So whats the next word, then? Almost-no-math intro to transformer models

https://matthias-kainer.de/blog/posts/so-whats-the-next-word-then-/
1•oesimania•46m ago•0 comments

Ed Zitron: The Hater's Guide to Microsoft

https://bsky.app/profile/edzitron.com/post/3me7ibeym2c2n
2•vintagedave•49m ago•1 comments

UK infants ill after drinking contaminated baby formula of Nestle and Danone

https://www.bbc.com/news/articles/c931rxnwn3lo
1•__natty__•49m ago•0 comments

Show HN: Android-based audio player for seniors – Homer Audio Player

https://homeraudioplayer.app
3•cinusek•50m ago•2 comments

Starter Template for Ory Kratos

https://github.com/Samuelk0nrad/docker-ory
1•samuel_0xK•51m ago•0 comments

LLMs are powerful, but enterprises are deterministic by nature

2•prateekdalal•55m ago•0 comments

Make your iPad 3 a touchscreen for your computer

https://github.com/lemonjesus/ipad-touch-screen
2•0y•1h ago•1 comments

Internationalization and Localization in the Age of Agents

https://myblog.ru/internationalization-and-localization-in-the-age-of-agents
1•xenator•1h ago•0 comments

Building a Custom Clawdbot Workflow to Automate Website Creation

https://seedance2api.org/
1•pekingzcc•1h ago•1 comments
Open in hackernews

I Genetically Engineered *Myself* to Fix Lactose Intolerance [video]

https://www.youtube.com/watch?v=J3FcbFqSoQY
31•pinkmuffinere•1mo ago

Comments

rzmmm•1mo ago
I remember reading about this. A key piece of information which should perhaps be in the title of the video is that the "fix" is transient.
pinkmuffinere•1mo ago
There's an update video here: https://www.youtube.com/watch?v=aoczYXJeMY4

Apparently the fix lasted ~18 months

amelius•1mo ago
Could the same fix be applied again?
pinkmuffinere•1mo ago
I know almost nothing about bio, hopefully someone more knowledgeable can answer. But I had the same thought -- one treatment for 18 months of relief sounds great! even people that _are_ lactose tolerant often lose tolerance as they age, so it seems like this could have wide appeal. Do it ~30 times and you could be lactose-tolerant your whole life.
amelius•1mo ago
But wait, if you lose tolerance then there must be some other mechanism involved because your genes stay the same as you age.
pinkmuffinere•1mo ago
He covers it in the video -- the cells lining your intestine are replaced as you age. Unless you get the lactose-tolerant gene into your stem cells, the newly-generated intestine lining will have your 'original' genetics, lacking the lactose tolerant gene. That said, it does sound like it's fading gradually for him, not a sudden drop off.
amelius•1mo ago
I was replying to this part of your comment:

"even people that _are_ lactose tolerant often lose tolerance as they age, so it seems like this could have wide appeal."

My point is that people who are lactose tolerant as a child will have the same genes when they are older. So gene editing should have no effect, unless the mechanism is more complicated somehow.

pinkmuffinere•1mo ago
Oh I see, that makes sense. Ya, I'm not sure how it works, maybe it has something to do with changing gene expression as we age? Ie, not the genes themselves changing, but the way that they are used / neglected? And then if that's the case, what would that mean for people that had taken this treatment? Perhaps they would see the age-related drop off, or perhaps it's different for some reason.
user070223•1mo ago
Thought Emporium entire channel is a goldmine

Here's another youtuber journey to fix the lactose intolerance by just eating lactose(powdered milk)("prebiotic") which had strains of a bacteria("probiotic" which feasts on the prebiotic) that breaks down lactose survives in the microbiome https://www.youtube.com/watch?v=h90rEkbx95w