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HPV vaccination reduces oncogenic HPV16/18 prevalence from 16% to <1% in Denmark

https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2025.30.27.2400820
47•stared•2h ago

Comments

kasperni•19m ago
It has really been a great success in Denmark.

In the 1960s, more than 900 people were diagnosed with cervical cancer each year, corresponding to more than 40 cases per 100,000 Danes.

Today, that number is below 10 per 100,000 nationwide – and among women aged 20 to 29, only 3 out of 100,000 are affected. This is below the WHO’s threshold for elimination of the disease.

garbawarb•19m ago
> Infection with HPV types covered by the vaccine (HPV16/18) has been almost eliminated. Before vaccination, the prevalence of HPV16/18 was between 15–17%, which has decreased in vaccinated women to < 1% by 2021. However, about one-third of women still had HPV infection with non-vaccine high-risk HPV types, and new infections with these types were more frequent in vaccinated than in unvaccinated women.

I wonder if we'll those non-vaccine strains will eventually become the most prevalent.

Traubenfuchs•15m ago
Everyone already knows!

HPV vaccination leads to massive reduction in nasopharyngeal, penile and rectal cancer in men.

The focus of messaging around HPV vaccination on ovarian cancer, female fertility and the age limitations for recommendations / free vaccination in some places are nothing short of a massive public health failure and almost scandal.

Just truthfully tell the boys their dicks might fall off and see how all of them quicklky flock to the vaccine.

blell•3m ago
Yes, blame the men, of course.
coreyh14444•7m ago
Just a quick point as an American living in Denmark, one of the reasons government programs like this work so well is everything is delivered digitally. We have "e-boks" https://en.digst.dk/systems/digital-post/about-the-national-... official government facilitated inboxes so when they need to notify you of vaccinations or whatever else, it arrives to your inbox. And basically 100% of residents use these systems.
nextos•6m ago
Lots of viruses are really oncogenic. The real success here is the ability of Denmark to track effectiveness. It sounds crazy but most countries do not have electronic health record capability to measure the effect of many interventions at population scale. Once good EHRs are rolled out, we will be able to double down on effective interventions, like this one, and vice versa.
spiderfarmer•3m ago
Sadly, no matter how good the data is, some societies will value opinions of uninformed celebrities above facts and reason, leading to a resurgence of preventable diseases.

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