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Show HN: Mcproxy – Filter unused MCP tools to save context in Claude Code

https://github.com/team-attention/mcproxy
1•changhoi•15s ago•0 comments

The Early Days of American Imperialism

https://www.theatlantic.com/newsletters/2026/01/old-american-imperialism-trump-power-abroad/685558/
1•petethomas•3m ago•0 comments

I6P: An IPv6-only P2P transport layer in Go (QUIC and ratchet)

https://github.com/TheusHen/I6P
1•TheusHen•7m ago•1 comments

Plaza.one

https://plaza.one/
1•indigodaddy•7m ago•0 comments

Show HN: ApiTap – Stream APIs to any Data Warehouse with SQL (Rust + DataFusion)

https://apitap.dev/
1•kotekaman•7m ago•0 comments

Slopware.wtf – Roasting AI-Generated Garbage Software

https://slopware.wtf/
1•airhangerf15•8m ago•0 comments

Cchistory: Track Claude Code system prompts over time

https://cchistory.mariozechner.at/
1•handfuloflight•8m ago•0 comments

Show HN: I built an AI that calls you until you wake up

https://wakecall.online/
1•rahma_tm•19m ago•1 comments

SHP: 700x faster context recall by treating memory as network

https://github.com/silentnoisehun/Silent-Hope-Protocol
1•Hope_Genom•20m ago•1 comments

A Year of Typing: My NumPy Fellowship Retrospective

https://blog.scientific-python.org/numpy/fellowship-program-2025-retrospective/
1•todsacerdoti•22m ago•0 comments

Anthropic bans use of API in OpenCode CLI tool

https://github.com/anomalyco/opencode/issues/7410
4•sergiotapia•22m ago•1 comments

We just open sourced the code-simplifier agent we use on the Claude Code team

https://twitter.com/bcherny/status/2009450715081789767
1•cleanexit0•22m ago•0 comments

SFC vs. VIZIO: who can enforce the GPL?

https://lwn.net/SubscriberLink/1052734/5903e175673caeef/
2•pabs3•24m ago•0 comments

GPLv2 and Installation Requirements

https://lwn.net/SubscriberLink/1052842/52c45fb8bcc3fade/
1•pabs3•25m ago•0 comments

Show HN: Open-source multimodal AI that runs in the browser

https://johnjboren.github.io/ai-assistant.html
1•EschatonCometh•26m ago•0 comments

Show HN: Layoffstoday – Open database tracking for 10k Companies

https://layoffstoday.io/
1•doremon0902•27m ago•0 comments

Pituffik Space Base

https://en.wikipedia.org/wiki/Pituffik_Space_Base
2•CGMthrowaway•28m ago•0 comments

From old English to modern American English in one monologue

https://www.youtube.com/watch?v=842OX2_vCic
1•gk1•28m ago•0 comments

Financial Hardship Shows Up in Baby Brains

https://nautil.us/how-financial-hardship-shows-up-in-baby-brains-1260476/
1•fleahunter•30m ago•0 comments

Testing 2 open-weight models across coding tasks: GLM 4.7 and MiniMax M2.1

https://blog.kilo.ai/p/open-weight-models-are-getting-serious
1•heymax054•30m ago•0 comments

When AI writes almost all code, what happens to software engineering?

https://newsletter.pragmaticengineer.com/p/when-ai-writes-almost-all-code-what
3•Brajeshwar•34m ago•0 comments

Show HN: A commitment model for usage billing

https://twitter.com/tryflexprice/status/2009226683849773430
1•sudeepsd__•34m ago•0 comments

Trump Lays Out a Vision of Power Restrained Only by 'My Own Morality'

https://www.nytimes.com/2026/01/08/us/politics/trump-interview-power-morality.html
10•Stevvo•35m ago•0 comments

Ask AI via Lightning payments (no accounts, no API keys, no stored history)

https://satsforai.com/
1•LightProx•37m ago•1 comments

The most popular Go dependency is

https://blog.thibaut-rousseau.com/blog/the-most-popular-go-dependency-is/
1•bzGoRust•41m ago•0 comments

Ralph Wiggum Experiment – Can AI meaningfully improve through iterative loops?

https://github.com/UtpalJayNadiger/ralphwiggumexperiment
1•iacguy•42m ago•0 comments

Implementing a web server in a single printf() call (2014)

https://tinyhack.com/2014/03/12/implementing-a-web-server-in-a-single-printf-call/
1•nateb2022•42m ago•1 comments

Kelly Evans: Goodbye, Google

https://www.cnbc.com/2026/01/07/kelly-evans-goodbye-google.html
1•cebert•46m ago•1 comments

Spirit Cave Resilience: How Do We Explain a 10k-Year Continuity

https://www.cambridge.org/core/journals/american-antiquity/article/spirit-cave-resilience-how-do-...
1•1659447091•48m ago•0 comments

Show HN: LSP Skill – IntelliSense for Coding Agents That Works

https://lsp-client.github.io/
1•observerw•54m ago•0 comments
Open in hackernews

Covid-19 leaves a lasting mark on the human brain

https://news.griffith.edu.au/2025/12/16/covid-19-leaves-a-lasting-mark-on-the-human-brain/
42•amichail•22h ago

Comments

rippeltippel•21h ago
The article doesn't say what those lasting marks are, nor their possible effects. Does anyone have any details on that?
napkinartist•21h ago
They link to the paper in the article: https://www.sciencedirect.com/science/article/pii/S266635462...
vizzier•20h ago
Still fairly non specific, as science probably should be (the question was if there visible MRI detectable changes, not what specific downstream changes were apparent)

Interesting that if we can detect some of these changes with covid what other viruses might be doing to us up there.

euroderf•17h ago
This sounds a bit like the opening scene of something science fiction-ey dreadful. Like, even Pluribus.
kazinator•21h ago
> The NCNED brings together a critical mass of talented researchers and clinicians committed to improving the lives of the patients.

Of course, improving the lives of patients for $$$!

First you have to convince people that they have a problem, and their insurers that it's covered.

It's the perfect disease. Scare people into suspecting they have it. All the hypochondriacs will believe it. It's difficult to measure and impossible to confirm recovery; you can milk that cow to kingdom come.

defrost•20h ago
It's not US Pharma here, it's an Australian University (a country that actively works to keep health costs low and outcomes high) doing work funded by two outcomes orientated charities:

* https://qbi.uq.edu.au/stafford-fox-medical-research-foundati...

* https://www.meresearch.org.uk/

It's difficult to see a Martin Shkreli exploiting warped U.S. regulatory incentives parallel.

Frieren•20h ago
> Our study identified altered signal intensity, abnormal tissue microstructure, and imbalanced neurochemicals in long COVID and COVID-19 recovered healthy controls.

So, it seems that it has long lasting effects on everybody. The main difference is how severe are that effects.

> Structural MRI studies have also identified alterations in brain morphology among COVID-RHC, including reductions in grey matter volume, thickness and global brain volume when compared with healthy controls

That is scary.

> Furthermore, long-term follow-up studies are crucial to determine whether the identified brain changes are progressive, stable or dynamic over time.

This is interesting, thou. Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.

krackers•20h ago
>Importantly, cognitive impairments are not limited to those with ongoing systemic symptoms; they are also evident in COVID-19 recovered individuals (COVID-RHC) who no longer report active symptoms, compared to healthy controls without SARS-CoV-2 infection (Non-COVID-HC) (Hampshire et al., 2021)

The finding was done in 2021, it's not clear to me if it's an issue years out or it's just a manifestation of post-viral syndrome. Also today there are unlikely to be any people who haven't been infected by sars-cov2

fractallyte•20h ago
> Also today there are unlikely to be any people who haven't been infected by sars-cov2

We do exist... ;-)

throwaway290•18h ago
Most covid19 infections are asymptomatic so unless you treat every day you can't know;)
AstralStorm•16h ago
Well, even the antibody titre isn't foolproof (some people do not react or have their immune system later wiped). However having no antibody titre is pretty good sign you never had it. Not sure if there's a portable cheap blood test for it yet. Should be one, like for the active disease.
throwaway290•8h ago
I heard antibodies are not permanent? not sure
swed420•14h ago
Yep. Anybody who wears a well-fitting N95 wherever they go is in a rather safe place.

Breakthrough infections are still technically possible, but quite unlikely.

swed420•14h ago
> Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.

Some symptoms of long COVID do lessen over time. The problem is that anybody who doesn't take adequate preventative measures (vast majority) are constantly re-infecting themselves every 6-12 months, so their body never has a chance to recover.

Even vaccinated individuals are not safe. The only real protection is regular use of a well fitting N95 in public spaces, and making sure everyone in your household does the same.

DustinEchoes•11h ago
Brain matter losses don’t usually get better.
readthenotes1•12h ago
Similar changes from taking the vaccine?