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Queueing Theory v2: DORA metrics, queue-of-queues, chi-alpha-beta-sigma notation

https://github.com/joelparkerhenderson/queueing-theory
1•jph•6m ago•0 comments

Show HN: Hibana – choreography-first protocol safety for Rust

https://hibanaworks.dev/
1•o8vm•8m ago•0 comments

Haniri: A live autonomous world where AI agents survive or collapse

https://www.haniri.com
1•donangrey•9m ago•1 comments

GPT-5.3-Codex System Card [pdf]

https://cdn.openai.com/pdf/23eca107-a9b1-4d2c-b156-7deb4fbc697c/GPT-5-3-Codex-System-Card-02.pdf
1•tosh•22m ago•0 comments

Atlas: Manage your database schema as code

https://github.com/ariga/atlas
1•quectophoton•25m ago•0 comments

Geist Pixel

https://vercel.com/blog/introducing-geist-pixel
1•helloplanets•27m ago•0 comments

Show HN: MCP to get latest dependency package and tool versions

https://github.com/MShekow/package-version-check-mcp
1•mshekow•35m ago•0 comments

The better you get at something, the harder it becomes to do

https://seekingtrust.substack.com/p/improving-at-writing-made-me-almost
2•FinnLobsien•37m ago•0 comments

Show HN: WP Float – Archive WordPress blogs to free static hosting

https://wpfloat.netlify.app/
1•zizoulegrande•38m ago•0 comments

Show HN: I Hacked My Family's Meal Planning with an App

https://mealjar.app
1•melvinzammit•38m ago•0 comments

Sony BMG copy protection rootkit scandal

https://en.wikipedia.org/wiki/Sony_BMG_copy_protection_rootkit_scandal
1•basilikum•41m ago•0 comments

The Future of Systems

https://novlabs.ai/mission/
2•tekbog•42m ago•1 comments

NASA now allowing astronauts to bring their smartphones on space missions

https://twitter.com/NASAAdmin/status/2019259382962307393
2•gbugniot•46m ago•0 comments

Claude Code Is the Inflection Point

https://newsletter.semianalysis.com/p/claude-code-is-the-inflection-point
3•throwaw12•48m ago•1 comments

Show HN: MicroClaw – Agentic AI Assistant for Telegram, Built in Rust

https://github.com/microclaw/microclaw
1•everettjf•48m ago•2 comments

Show HN: Omni-BLAS – 4x faster matrix multiplication via Monte Carlo sampling

https://github.com/AleatorAI/OMNI-BLAS
1•LowSpecEng•49m ago•1 comments

The AI-Ready Software Developer: Conclusion – Same Game, Different Dice

https://codemanship.wordpress.com/2026/01/05/the-ai-ready-software-developer-conclusion-same-game...
1•lifeisstillgood•51m ago•0 comments

AI Agent Automates Google Stock Analysis from Financial Reports

https://pardusai.org/view/54c6646b9e273bbe103b76256a91a7f30da624062a8a6eeb16febfe403efd078
1•JasonHEIN•54m ago•0 comments

Voxtral Realtime 4B Pure C Implementation

https://github.com/antirez/voxtral.c
2•andreabat•56m ago•1 comments

I Was Trapped in Chinese Mafia Crypto Slavery [video]

https://www.youtube.com/watch?v=zOcNaWmmn0A
2•mgh2•1h ago•0 comments

U.S. CBP Reported Employee Arrests (FY2020 – FYTD)

https://www.cbp.gov/newsroom/stats/reported-employee-arrests
1•ludicrousdispla•1h ago•0 comments

Show HN: I built a free UCP checker – see if AI agents can find your store

https://ucphub.ai/ucp-store-check/
2•vladeta•1h ago•1 comments

Show HN: SVGV – A Real-Time Vector Video Format for Budget Hardware

https://github.com/thealidev/VectorVision-SVGV
1•thealidev•1h ago•0 comments

Study of 150 developers shows AI generated code no harder to maintain long term

https://www.youtube.com/watch?v=b9EbCb5A408
2•lifeisstillgood•1h ago•0 comments

Spotify now requires premium accounts for developer mode API access

https://www.neowin.net/news/spotify-now-requires-premium-accounts-for-developer-mode-api-access/
1•bundie•1h ago•0 comments

When Albert Einstein Moved to Princeton

https://twitter.com/Math_files/status/2020017485815456224
1•keepamovin•1h ago•0 comments

Agents.md as a Dark Signal

https://joshmock.com/post/2026-agents-md-as-a-dark-signal/
2•birdculture•1h ago•1 comments

System time, clocks, and their syncing in macOS

https://eclecticlight.co/2025/05/21/system-time-clocks-and-their-syncing-in-macos/
1•fanf2•1h ago•0 comments

McCLIM and 7GUIs – Part 1: The Counter

https://turtleware.eu/posts/McCLIM-and-7GUIs---Part-1-The-Counter.html
2•ramenbytes•1h ago•0 comments

So whats the next word, then? Almost-no-math intro to transformer models

https://matthias-kainer.de/blog/posts/so-whats-the-next-word-then-/
1•oesimania•1h ago•0 comments
Open in hackernews

Covid-19 leaves a lasting mark on the human brain

https://news.griffith.edu.au/2025/12/16/covid-19-leaves-a-lasting-mark-on-the-human-brain/
42•amichail•1mo ago

Comments

rippeltippel•1mo ago
The article doesn't say what those lasting marks are, nor their possible effects. Does anyone have any details on that?
napkinartist•1mo ago
They link to the paper in the article: https://www.sciencedirect.com/science/article/pii/S266635462...
vizzier•1mo ago
Still fairly non specific, as science probably should be (the question was if there visible MRI detectable changes, not what specific downstream changes were apparent)

Interesting that if we can detect some of these changes with covid what other viruses might be doing to us up there.

euroderf•1mo ago
This sounds a bit like the opening scene of something science fiction-ey dreadful. Like, even Pluribus.
kazinator•1mo ago
> The NCNED brings together a critical mass of talented researchers and clinicians committed to improving the lives of the patients.

Of course, improving the lives of patients for $$$!

First you have to convince people that they have a problem, and their insurers that it's covered.

It's the perfect disease. Scare people into suspecting they have it. All the hypochondriacs will believe it. It's difficult to measure and impossible to confirm recovery; you can milk that cow to kingdom come.

defrost•1mo ago
It's not US Pharma here, it's an Australian University (a country that actively works to keep health costs low and outcomes high) doing work funded by two outcomes orientated charities:

* https://qbi.uq.edu.au/stafford-fox-medical-research-foundati...

* https://www.meresearch.org.uk/

It's difficult to see a Martin Shkreli exploiting warped U.S. regulatory incentives parallel.

Frieren•1mo ago
> Our study identified altered signal intensity, abnormal tissue microstructure, and imbalanced neurochemicals in long COVID and COVID-19 recovered healthy controls.

So, it seems that it has long lasting effects on everybody. The main difference is how severe are that effects.

> Structural MRI studies have also identified alterations in brain morphology among COVID-RHC, including reductions in grey matter volume, thickness and global brain volume when compared with healthy controls

That is scary.

> Furthermore, long-term follow-up studies are crucial to determine whether the identified brain changes are progressive, stable or dynamic over time.

This is interesting, thou. Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.

krackers•1mo ago
>Importantly, cognitive impairments are not limited to those with ongoing systemic symptoms; they are also evident in COVID-19 recovered individuals (COVID-RHC) who no longer report active symptoms, compared to healthy controls without SARS-CoV-2 infection (Non-COVID-HC) (Hampshire et al., 2021)

The finding was done in 2021, it's not clear to me if it's an issue years out or it's just a manifestation of post-viral syndrome. Also today there are unlikely to be any people who haven't been infected by sars-cov2

fractallyte•1mo ago
> Also today there are unlikely to be any people who haven't been infected by sars-cov2

We do exist... ;-)

throwaway290•1mo ago
Most covid19 infections are asymptomatic so unless you treat every day you can't know;)
AstralStorm•4w ago
Well, even the antibody titre isn't foolproof (some people do not react or have their immune system later wiped). However having no antibody titre is pretty good sign you never had it. Not sure if there's a portable cheap blood test for it yet. Should be one, like for the active disease.
throwaway290•4w ago
I heard antibodies are not permanent? not sure
swed420•4w ago
Yep. Anybody who wears a well-fitting N95 wherever they go is in a rather safe place.

Breakthrough infections are still technically possible, but quite unlikely.

swed420•4w ago
> Is it permanent, it gets worse or better? That makes a big difference and it may also justify further studies and actions.

Some symptoms of long COVID do lessen over time. The problem is that anybody who doesn't take adequate preventative measures (vast majority) are constantly re-infecting themselves every 6-12 months, so their body never has a chance to recover.

Even vaccinated individuals are not safe. The only real protection is regular use of a well fitting N95 in public spaces, and making sure everyone in your household does the same.

DustinEchoes•4w ago
Brain matter losses don’t usually get better.
readthenotes1•4w ago
Similar changes from taking the vaccine?