fp.

Yeast Programmed for Opioid Total Synthesis

https://cen.acs.org/articles/93/i49/Yeast-Programmed-Opioid-Total-Synthesis.html

1•slow_typist•3m ago•0 comments

Google employee made redundant after reporting sexual harassment, court hears

https://www.bbc.co.uk/news/articles/c62v51d1ry2o

1•latein•4m ago•0 comments

HeyToken – Access all LLMs for 30% less via a unified API

https://heytoken.ai

1•alhazar•7m ago•1 comments

Create Google API credentials in 50 easy steps

https://github.com/glotlabs/gdrive/blob/main/docs/create_google_api_credentials.md

1•ukuina•9m ago•0 comments

Setting Up OpenCode with Local Models

https://theaiops.substack.com/p/setting-up-opencode-with-local-models

1•ramikrispin•11m ago•0 comments

Amazon Redshift AutoWLM and SQA internals plus commentary (and a bit on CSC)

1•Max-Ganz-II•13m ago•0 comments

LitePoint clears testing milestone with Qualcomm's upcoming Wi-Fi 8 platform

https://www.rcrwireless.com/20260109/test-measurement/ces-2026-litepoint-clears-testing-milestone...

1•lordwiz•13m ago•0 comments

UI Skills

https://www.ui-skills.com/

2•handfuloflight•15m ago•0 comments

Eat More Deer

https://www.theatlantic.com/health/2026/01/deer-hunting-venison-sale/685537/

2•thunderbong•18m ago•0 comments

The Score

https://www.penguin.co.uk/books/457380/the-score-by-nguyen-c-thi/9780241653975

1•molteanu•19m ago•0 comments

Anthropic: Demystifying Evals for AI Agents

https://www.anthropic.com/engineering/demystifying-evals-for-ai-agents

2•Bayram•21m ago•0 comments

New Game Launcher for PC Games

https://www.gamekolektor.com/

1•ravioldevuy•21m ago•1 comments

Show HN: MCP for browsing, searching, exporting, backing up Cursor chat history

https://github.com/S2thend/cursor-history-mcp

2•mikasisiki•35m ago•2 comments

Signal Chat: Silicon Valley Is Plotting Against California's Billionaire Tax

https://www.wsj.com/politics/policy/save-california-billionare-tax-814a2fe9

4•1vuio0pswjnm7•41m ago•1 comments

Obscene images: X admits its mistake and stated it would comply with Indian law

https://timesofindia.indiatimes.com/india/obscene-image-row-x-admits-mistake-thousands-of-posts-o...

2•throwaway110001•46m ago•0 comments

Photos of the Forgotten

https://www.synthetrix.com/potf.html

2•exvi•50m ago•0 comments

'Fuck You, Make Me' Without Saying the Words

https://daringfireball.net/2026/01/fuck_you_make_me_without_saying_the_words

5•nopakos•55m ago•2 comments

Show HN: I built an Instagram-style productivity app with gamification

https://apps.apple.com/us/app/lockin-social-productivity/id6742454713

2•mandynoee•1h ago•1 comments

The Concise TypeScript Book

https://github.com/gibbok/typescript-book

11•javatuts•1h ago•1 comments

Worktrunk – A CLI tool to manage multiple worktrees in Git repositories

https://github.com/max-sixty/worktrunk

2•javatuts•1h ago•0 comments

Jupyter Agents: training LLMs to reason with notebooks

https://huggingface.co/blog/jupyter-agent-2

2•walterbell•1h ago•0 comments

What's the end game for Ghost newsletter sign-up spam?

https://www.autodidacts.io/ghost-newsletter-sign-up-spam/

4•Curiositry•1h ago•0 comments

A multimodal sleep foundation model for disease prediction

https://www.nature.com/articles/s41591-025-04133-4

2•gnabgib•1h ago•0 comments

Quake 1 Single-Player Map Design Theories (2001)

https://www.quaddicted.com/webarchive//teamshambler.planetquake.gamespy.com/theories1.html

2•Lammy•1h ago•1 comments

Panoply of the Weird

https://www.nybooks.com/articles/2026/01/15/panoply-of-the-weird-fitz-james-obrien/

1•mitchbob•1h ago•1 comments

Sovereign Tech Fund: Strategic investments in the digital infrastructure

https://www.sovereign.tech/programs/fund

1•teleforce•1h ago•1 comments

Show HN: WinBorg, a beautiful alternative to Vorta for BorgBackup

https://github.com/robotnikz/WinBorg

2•robotnikz•1h ago•0 comments

Reversible Computation as a software construction paradigm

1•Nivdc•1h ago•1 comments

Writing First, Tooling Second

https://susam.net/writing-first-tooling-second.html

2•Brajeshwar•1h ago•0 comments

How can I grep for lines containing foo AND bar, foo OR bar?

https://mywiki.wooledge.org/BashFAQ/079

1•kamaraju•1h ago•1 comments

Yeast Programmed for Opioid Total Synthesis

Google employee made redundant after reporting sexual harassment, court hears

HeyToken – Access all LLMs for 30% less via a unified API

Create Google API credentials in 50 easy steps

Setting Up OpenCode with Local Models

Amazon Redshift AutoWLM and SQA internals plus commentary (and a bit on CSC)

LitePoint clears testing milestone with Qualcomm's upcoming Wi-Fi 8 platform

UI Skills

Eat More Deer

The Score

Anthropic: Demystifying Evals for AI Agents

New Game Launcher for PC Games

Show HN: MCP for browsing, searching, exporting, backing up Cursor chat history

Signal Chat: Silicon Valley Is Plotting Against California's Billionaire Tax

Obscene images: X admits its mistake and stated it would comply with Indian law

Photos of the Forgotten

'Fuck You, Make Me' Without Saying the Words

Show HN: I built an Instagram-style productivity app with gamification

The Concise TypeScript Book

Worktrunk – A CLI tool to manage multiple worktrees in Git repositories

Jupyter Agents: training LLMs to reason with notebooks

What's the end game for Ghost newsletter sign-up spam?

A multimodal sleep foundation model for disease prediction

Quake 1 Single-Player Map Design Theories (2001)

Panoply of the Weird

Sovereign Tech Fund: Strategic investments in the digital infrastructure

Show HN: WinBorg, a beautiful alternative to Vorta for BorgBackup

Reversible Computation as a software construction paradigm

Writing First, Tooling Second

How can I grep for lines containing foo AND bar, foo OR bar?

When Governments Block Free Speech, Block Legal Reach with Offshore Web Hosting

Comments

Yeast Programmed for Opioid Total Synthesis

Google employee made redundant after reporting sexual harassment, court hears

HeyToken – Access all LLMs for 30% less via a unified API

Create Google API credentials in 50 easy steps

Setting Up OpenCode with Local Models

Amazon Redshift AutoWLM and SQA internals plus commentary (and a bit on CSC)

LitePoint clears testing milestone with Qualcomm's upcoming Wi-Fi 8 platform

UI Skills

Eat More Deer

The Score

Anthropic: Demystifying Evals for AI Agents

New Game Launcher for PC Games

Show HN: MCP for browsing, searching, exporting, backing up Cursor chat history

Signal Chat: Silicon Valley Is Plotting Against California's Billionaire Tax

Obscene images: X admits its mistake and stated it would comply with Indian law

Photos of the Forgotten

'Fuck You, Make Me' Without Saying the Words

Show HN: I built an Instagram-style productivity app with gamification

The Concise TypeScript Book

Worktrunk – A CLI tool to manage multiple worktrees in Git repositories

Jupyter Agents: training LLMs to reason with notebooks

What's the end game for Ghost newsletter sign-up spam?

A multimodal sleep foundation model for disease prediction

Quake 1 Single-Player Map Design Theories (2001)

Panoply of the Weird

Sovereign Tech Fund: Strategic investments in the digital infrastructure

Show HN: WinBorg, a beautiful alternative to Vorta for BorgBackup

Reversible Computation as a software construction paradigm

Writing First, Tooling Second

How can I grep for lines containing foo AND bar, foo OR bar?