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AI-Designed Antibodies Are Racing Toward Clinical Trials

https://singularityhub.com/2026/01/13/ai-designed-antibodies-race-toward-clinical-trials/
1•Brajeshwar•49s ago•0 comments

To Have Machines Make Math Proofs, Turn Them into a Puzzle

https://www.quantamagazine.org/to-have-machines-make-math-proofs-turn-them-into-a-puzzle-20251110/
1•Brajeshwar•56s ago•0 comments

How did birds evolve? The answer is wilder than anyone thought

https://www.nature.com/articles/d41586-026-00076-z
1•Brajeshwar•1m ago•0 comments

China announces record $1.2T trade surplus despite Trump tariffs

https://www.bbc.com/news/articles/c9wx1v84rzyo
2•voxadam•2m ago•0 comments

Dell tells staff to get ready for the biggest transformation in company history

https://www.businessinsider.com/dell-jeff-clarke-ai-memo-biggest-transformation-in-company-histor...
1•taubek•3m ago•0 comments

How to sell a company in a niche category? [video]

https://www.youtube.com/watch?v=xN0ZTKKNHAc
1•mooreds•3m ago•0 comments

Show HN: Cadence Spanish – AI audio lessons to learn Spanish

https://cadencespanish.com/
1•aliclark•3m ago•0 comments

NASA, Department of Energy to Develop Lunar Surface Reactor by 2030

https://spaceanddefense.io/nasa-department-of-energy-to-develop-lunar-surface-reactor-by-2030/
1•smurda•3m ago•0 comments

Scaling Data Safety at Gaia: Detecting PII and Phi in the Data Warehouse

https://medium.com/gaia-family/scaling-data-safety-at-gaia-detecting-pii-and-phi-in-the-data-ware...
1•mooreds•4m ago•0 comments

The All-New Slackbot: Your Personal AI Agent for Work

https://slack.com/blog/news/slackbot-context-aware-ai-agent-for-work?nojsmode=1
1•josephwegner•4m ago•0 comments

Show HN: Skillshare – Sync skills across AI CLI tools

https://github.com/runkids/skillshare
2•runkids•4m ago•0 comments

For 21 years, enthusiasts used their home computers to search for ET

https://news.berkeley.edu/2026/01/12/for-21-years-enthusiasts-used-their-home-computers-to-search...
1•geox•6m ago•0 comments

The Wage-Volume Paradox in Rural H-1B Physician Recruitment

https://theh1brecords.substack.com/p/rural-healthcare-h1b-wage-paradox
1•codebyaditya•8m ago•1 comments

Exploring MSX-DOS and CP/M on OneChipBook FPGA-Powered Laptop

https://www.toughdev.com/content/2025/09/exploring-msx-dos-and-cpm-on-onechipbook-fpga-powered-la...
1•voxadam•8m ago•0 comments

My Fitbit Buzzed and I Understood Enshittification

https://tidyfirst.substack.com/p/my-fitbit-buzzed-and-i-understood
1•dannyrosen•8m ago•0 comments

Show HN: Sommo – AI-native wine learning app

https://sommo.app
1•gokh•10m ago•0 comments

FBI raids Washington Post reporter's home in 'highly unusual and aggressive' act

https://www.theguardian.com/us-news/2026/jan/14/fbi-raid-washington-post-hannah-natanson
5•echelon_musk•10m ago•0 comments

Using Linear Algebra to Predict a Non-Linear Pendulum

https://chillphysicsenjoyer.substack.com/p/using-linear-algebra-to-predict-a
1•surprisetalk•13m ago•0 comments

Nothing will change your life more than saying what you want to say

https://www.avabear.xyz/p/nothing-will-change-your-life-more
2•surprisetalk•13m ago•0 comments

Macintosh Garden

https://macintoshgarden.org/
1•surprisetalk•13m ago•0 comments

Getting to sub-300ms microVM sandboxes for automation and AI agents

https://slicervm.com/blog/microvms-sandboxes-in-300ms/
1•alexellisuk•13m ago•1 comments

How Generative AI is destroying society

https://garymarcus.substack.com/p/how-generative-ai-is-destroying-society
2•flail•13m ago•0 comments

US freezes all visa processing for 75 countries, including Somalia, Russia, Iran

https://www.foxnews.com/politics/us-freezes-all-visa-processing-75-countries-including-somalia-ru...
1•garbawarb•15m ago•0 comments

Show HN: Daily LinkedIn Pinpoint Puzzle Answers (PinpointAnswer Today)

https://www.pinpointanswers.online/
1•hoxihan•16m ago•0 comments

Show HN: Histoday – On This Day in History

https://histoday.net/
1•jsxyzb•16m ago•0 comments

Show HN: Your Domains Wrapped - A 2025 domain recap

https://domained.app/wrapped
1•joggez•17m ago•0 comments

UK nudification app ban won't apply to Elon Musk's Grok

https://www.politico.eu/article/uk-nudification-app-ban-wont-apply-to-elon-musks-grok/
3•miohtama•17m ago•0 comments

Show HN: HotspotPeek – Track iPhone hotspot data usage from Mac menu bar

https://anhphong.dev/apps/hotspot-peek/
1•anhphong•18m ago•1 comments

The First Solid-State Vehicle May Be a Motorcycle

https://spectrum.ieee.org/ces-2026-solid-state-batteries
1•voxadam•18m ago•0 comments

Hydrophone Review: Ambient ASF-1, ASF-2, Aquarian Audio, JrF

https://zachpoff.com/resources/hydrophone-review-ambient-asf-1-asf-2-aquarian-audio-jrf/
1•teleforce•19m ago•0 comments
Open in hackernews

The PICO-8 fantasy console

https://www.lexaloffle.com/pico-8.php
2•brainlessdev•1h ago