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Show HN: Opengenepool, MolBio IDE Plugin

https://opengenepool.vidalalabs.com
2•dnautics•2h ago
I had a 14+year old project that got waylaid for years and frustrated (and losing time) with existing Molecular Biology SAASes, I used AI assisted coding to update the project to Vue.js and bring it back. This Vue.js component has all the basics that a working molecular biologist could want, and way less footguns.

Minnesota wants to win a war of attrition

https://www.theverge.com/policy/863632/minnesota-walz-trump-sousveillance-ice
1•andrewstetsenko•1m ago•0 comments

Tesla, BYD, and Xiaomi Are Playing Different Games

https://gilpignol.substack.com/p/tesla-byd-and-xiaomi-are-playing
1•light_triad•1m ago•0 comments

Nebra Sky Disc: the oldest depiction of astronomical phenomena

https://www.livescience.com/archaeology/nebra-sky-disc-the-worlds-oldest-depiction-of-astronomica...
1•janandonly•2m ago•0 comments

Generating Distinct AI Voice Performances by Prompt Engineering GPT-4o

https://minimaxir.com/2024/10/speech-prompt-engineering/
1•7777777phil•2m ago•0 comments

I Improved Claude's MCP-CLI Experimental MCP Fix – 18x speedup on 50 calls

1•AIntelligentTec•3m ago•0 comments

Of donkeys, mules, and horses: data structures for network prefixes in Rust

https://blog.nlnetlabs.nl/donkeys-mules-horses/
1•fanf2•3m ago•0 comments

Gravity from Information Geometry: A Lean 4 Formalization of Emergent Spacetime

https://www.academia.edu/146192044/Gravity_from_Information_Geometry_A_Lean_4_Formalization_of_Em...
1•kristintynski•5m ago•1 comments

Software Is Fine

https://shomik.substack.com/p/software-is-fine
1•mooreds•5m ago•0 comments

Do not give up your brain

https://cassidoo.co/post/good-brain/
1•mooreds•5m ago•0 comments

Use Social Media Mindfully

https://danielleheberling.xyz/blog/mindful-social-media/
2•mooreds•6m ago•0 comments

Tell HN: Deskflow is getting spammed with AI-slop PRs

1•acheong08•6m ago•0 comments

Google Mandiant Delivers the Coup de Grâce to Microsoft's NTLM

https://www.heise.de/en/news/Windows-Networks-Google-Mandiant-Delivers-the-Coup-de-Grace-to-Micro...
2•croes•6m ago•0 comments

Apple's "Protect Mail Activity" Doesn't Work

https://www.grepular.com/Apples_Protect_Mail_Activity_Doesnt_Work
2•mike-cardwell•8m ago•0 comments

Targeted Bets: An alternative approach to the job hunt

https://www.seanmuirhead.com/blog/targeted-bets
1•seany62•10m ago•1 comments

Jazz – The Database That Syncs

https://jazz.tools/
1•aleksjess•11m ago•0 comments

Targeted Bets: An alternative approach to the job hunt

1•seany62•11m ago•0 comments

Nanotimetamps: Time-Stamped Data on Nano Block Lattice

https://github.com/SerJaimeLannister/nanotimestamp/wiki
1•Imustaskforhelp•12m ago•0 comments

Starlink users must opt out of all browsing data being used to train xAI models

https://twitter.com/cryps1s/status/2013345999826153943
5•pizza•12m ago•0 comments

Nobody knows how large software products work

https://www.seangoedecke.com/nobody-knows-how-software-products-work/
2•7777777phil•16m ago•0 comments

Moving from Java to Python (2014)

https://yusufaytas.com/moving-from-java-to-python/
3•jatwork•16m ago•0 comments

19 hacks to get your startup's first customers (I made $150k+)

https://twitter.com/hustle_fred/status/2013200865956426130
2•Farid_Sukurov•17m ago•0 comments

Lava Lamps in Cloudflare's Encryption

https://www.cloudflare.com/en-gb/learning/ssl/lava-lamp-encryption/
1•cl3misch•18m ago•0 comments

The assistant axis: situating and stabilizing the character of LLMs

https://www.anthropic.com/research/assistant-axis
3•mfiguiere•20m ago•0 comments

Multi-tenant SaaS is dead for mid-market (and why K8s namespaces are the future)

1•nthypes•22m ago•0 comments

Show HN: Shebe, a fast, simple and tiny code-search tool

https://github.com/rhobimd-oss/shebe
1•marwamc•24m ago•1 comments

Looking Back at the Best Inventions of 2001

https://shkspr.mobi/blog/2026/01/looking-back-at-the-best-inventions-of-2001/
3•7777777phil•24m ago•0 comments

Help Denmark Buy California – Because Why Not?

https://denmarkification.com/
4•embedding-shape•25m ago•3 comments

SoundSlab: How It Started

https://craigjb.com/2026/01/10/soundslab-beginning/
1•wibbily•28m ago•0 comments

AI in Biotech in 2026

https://www.benchling.com/biotech-ai-report-2026
1•asielen•30m ago•0 comments

S4 (Severe) Solar Radiation Storm in Progress

https://www.swpc.noaa.gov/news/s4-severe-solar-radiation-storm-progress-january-19th-2026
4•uticus•33m ago•1 comments