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Advancing regulatory variant effect prediction with AlphaGenome

https://www.nature.com/articles/s41586-025-10014-0
1•mellosouls•1h ago

Observation of Strong Nonreciprocal Thermal Emission

https://par.nsf.gov/biblio/10626678-observation-strong-nonreciprocal-thermal-emission
1•georgecmu•35s ago•0 comments

MicroPythonOS graphical operating system delivers Android-like user experience

https://www.cnx-software.com/2026/01/29/micropythonos-graphical-operating-system-delivers-android...
1•mikece•47s ago•0 comments

CGO-Free Implementation of CTAP/Fido 2 in Golang

https://github.com/mohammadv184/go-fido2
1•mohammadv184•1m ago•0 comments

Modeling identity and access hierarchy in Postgres with ltree

https://atlas9.dev/blog/iam-hierarchy.html
1•buchanae•1m ago•0 comments

Databases: Are We There Yet? – Spasov [video]

https://www.youtube.com/watch?v=Wu-OyLxiP88
1•adityaathalye•4m ago•1 comments

What's happening with code signing and future macOS?

https://eclecticlight.co/2026/01/17/whats-happening-with-code-signing-and-future-macos/
1•mpweiher•4m ago•0 comments

Trustless Digital – Trustful E-Babies Making

https://technopoliticsmusinings.substack.com/p/trustless-digital-trustful-e-babies
1•The1JDC•5m ago•0 comments

Book Review: The Mattering Instinct

https://www.nytimes.com/2026/01/28/books/review/the-mattering-instinct-rebecca-newberger-goldstei...
1•lxm•5m ago•0 comments

Siemens Overtakes SAP as Germany's Largest Firm by Market Value

https://www.bloomberg.com/news/articles/2026-01-29/siemens-overtakes-sap-as-germany-s-largest-fir...
2•wslh•7m ago•0 comments

Design for Amiability: Lessons from the Vienna Circle

https://alistapart.com/article/design-for-amiability-lessons-from-vienna/
1•evolve2k•7m ago•0 comments

The RAM Nightmare: How I Lost My Sanity (and Almost My Deadline)

https://www.davidrevoy.com/article1117/the-ram-nightmare-how-i-lost-my-sanity-and-almost-my-deadline
1•Tomte•7m ago•0 comments

How to Choose the Right Flight Instructor for Your Pilot Training – Skyfarer

https://skyfareracademy.com/p/how-to-choose-flight-instructor-for-pilot-training
1•skyfareracademy•7m ago•0 comments

Show HN: Argus-seal – Forensic-ready log integrity using Merkle Trees

https://github.com/gamer-null/argus-seal
1•gamer-null•8m ago•0 comments

Mozilla is building an AI 'rebel alliance' to take on OpenAI, Anthropic

https://www.cnbc.com/2026/01/27/mozilla-building-an-ai-rebel-alliance-to-take-on-openai-anthropic...
6•donutshop•9m ago•0 comments

Sweetening the deal for sustainability, while removing carbon dioxide

https://phys.org/news/2026-01-sweetening-sustainability-carbon-dioxide.html
1•PaulHoule•9m ago•0 comments

Trump officials met group pushing Alberta independence from Canada

https://www.ft.com/content/11dc2140-6a5d-4536-b766-52c920affcc7
3•throw0101a•9m ago•3 comments

Music publishers sue Anthropic for $3B over 'flagrant piracy' of 20k works

https://techcrunch.com/2026/01/29/music-publishers-sue-anthropic-for-3b-over-flagrant-piracy-of-2...
1•speckx•10m ago•0 comments

Show HN: Factor RSA Numbers as a Game

https://do-say-go.github.io/insights/
1•keepamovin•12m ago•1 comments

Pagelove: Building a better web – for humans and machines

https://page.love/blog/04-the-shape-of-pagelove.html
1•todsacerdoti•12m ago•0 comments

Launch HN: AgentMail (YC S25) – An API that gives agents their own email inboxes

4•Haakam21•12m ago•1 comments

Category Theory and Inclusivity

https://www.youtube.com/watch?v=HVMxSbJPr4g
1•todsacerdoti•14m ago•0 comments

Show HN: Kandle – A WebGPU-based ML library written from scratch in JavaScript

https://github.com/final-kk/kandle
2•finalkk•14m ago•2 comments

Show HN: Our command line tool to transpile AI Inference from Python to C++

https://github.com/muna-ai/muna-py
3•olokobayusuf•15m ago•0 comments

Show HN: Measuring runtime strain in autonomous AI systems

https://github.com/willshacklett/gvai-safety-systems
1•PapaShack45•16m ago•0 comments

How to Save Windows: Unsolicited Business Advice from a Concerned Former User

https://waldencui.com/post/save_microsoft_windows/
2•cui•16m ago•0 comments

Ask HN: Does ChatGPT 5.2 with web search still hallucinate facts?

1•logicallee•17m ago•1 comments

Does Anthropic believe its AI is conscious, or just want Claude to think so?

https://arstechnica.com/information-technology/2026/01/does-anthropic-believe-its-ai-is-conscious...
5•samizdis•19m ago•1 comments

Show HN: RTK – Simple CLI to reduce token usage in your LLM prompts

1•patrick4urcloud•20m ago•0 comments

Errors as Values in TypeScript

https://errore.org/
1•xmorse•22m ago•0 comments

AstraZeneca sets out $15B China investment during Starmer visit

https://www.reuters.com/business/healthcare-pharmaceuticals/astrazeneca-sets-out-15-billion-china...
1•DustinEchoes•24m ago•0 comments