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Advancing regulatory variant effect prediction with AlphaGenome

https://www.nature.com/articles/s41586-025-10014-0
1•granto•1h ago

Apple can't secure enough chips as iPhone demand surges, memory prices rise

https://www.cnbc.com/2026/01/29/apple-iphone-soc-memory-tsmc.html
2•1659447091•6m ago•0 comments

Apple Reports Record-Setting 1Q 2026 Results: $42.1B Profit on $143.8B Revenue

https://www.macrumors.com/2026/01/29/apple-1q-2026-earnings/
1•tosh•6m ago•0 comments

How linguistic framing in pitch decks influence investors' judgment – St. Gallen

https://www.pitchwise.se/blog/the-science-of-cold-outreach-a-research-on-why-your-pitch-deck-slid...
1•dabojula•11m ago•0 comments

AI creates asymmetric pressure on Open Source

https://dri.es/ai-creates-asymmetric-pressure-on-open-source
2•7777777phil•11m ago•0 comments

Show HN: Configlock, App Lock for Dotfiles

https://github.com/baggiiiie/configlock
1•baggiiiie•13m ago•0 comments

Cutting down 90% of database spending at Capacities by migrating to Postgres

https://capacities.io/blog/migration-to-postgres
1•steffenbleher•15m ago•1 comments

Show HN: Codeusse – mobile SSH with GUI file browser and LLM config gen

1•wrbl•15m ago•0 comments

Billionaires trying to prolong their life end up wasting it

https://www.thetimes.com/business/companies-markets/article/biohacking-longevity-anti-ageing-0rzf...
1•petethomas•16m ago•1 comments

Microsoft lost $357B in market cap as stock plunged most since 2020

https://www.cnbc.com/2026/01/29/microsoft-market-cap-earnings.html
4•1vuio0pswjnm7•17m ago•0 comments

Show HN: GetSheetAPI – Turn Any Google Sheet into a REST API in 60 Seconds

https://getsheetapi.com
1•sara_builds•19m ago•0 comments

Show HN: Subverted Academy – Rebelling against how cybersecurity is taught

https://academy.subverted.io
4•x_ulla•20m ago•2 comments

Ordercli – CLI for food delivery order history and tracking

https://github.com/steipete/ordercli
1•anupamchugh•22m ago•0 comments

Ask HN: Favourite Moltbot Extensions

1•janpmz•23m ago•0 comments

Benchmarking with Vulkan: the curse of variable GPU clock rates

https://mropert.github.io/2026/01/29/benchmarking_vulkan/
1•ingve•25m ago•0 comments

Google to pay $135M to settle Android data transfer lawsuit

https://www.reuters.com/sustainability/boards-policy-regulation/google-pay-135-million-settle-and...
3•1vuio0pswjnm7•25m ago•0 comments

Show HN: A simple, privacy-focused time ledger (no login required)

https://timekeeping.click/
1•dirkchou•28m ago•1 comments

Ashcan Comic

https://en.wikipedia.org/wiki/Ashcan_comic
1•benbreen•29m ago•0 comments

unfuck-microwave.sh

https://cofe.rocks/notice/B2gUBiWWuW3IyBpk6y
1•robin_reala•29m ago•0 comments

Treasures found on HS2 route stored in secret warehouse

https://www.bbc.co.uk/news/articles/c93v21q5xdvo
3•mellosouls•30m ago•0 comments

The Crypto CEO Who's Become Enemy No. 1 on Wall Street

https://www.wsj.com/finance/currencies/coinbase-ceo-brian-armstrong-wall-street-a7895786
1•1vuio0pswjnm7•33m ago•0 comments

Portugal builds Europe's first dedicated drone carrier, D João II

https://www.euronews.com/2026/01/29/portugal-builds-europes-first-dedicated-drone-carrier-d-joao-ii
1•saubeidl•35m ago•0 comments

AI Interview Coach

https://heroikk.info/voice-chat/
1•tikyda•38m ago•1 comments

Abusers using AI and digital tech to attack and control women, charity warns

https://www.theguardian.com/society/2026/jan/30/abusers-using-ai-and-digital-tech-to-attack-and-c...
1•zeristor•38m ago•0 comments

Show HN: I built a marketing operating system with long-term memory

https://theaicmo.com/
1•rogaai•40m ago•0 comments

UK's first rapid-charging battery train ready for boarding this weekend

https://www.theguardian.com/business/2026/jan/30/uk-first-rapid-charging-battery-train
1•zeristor•41m ago•0 comments

Trump threatens to tariff, decertify Canadian aircraft in latest trade war move

https://www.cbc.ca/news/politics/trump-tariffs-decertify-canadian-planes-9.7067498
1•N19PEDL2•42m ago•1 comments

Anthropic: AI Coding shows no productivity gains; impairs skill development

https://arxiv.org/abs/2601.20245
6•northfield27•49m ago•0 comments

The fat you can't see could be shrinking your brain

https://www.sciencedaily.com/releases/2026/01/260127112127.htm
2•1659447091•52m ago•0 comments

Landing Page Academy by Erik Kennedy

https://www.learnui.design/courses/landing-page-academy.html
1•nyratarg•57m ago•0 comments

Diversification Is Overrated

https://nox.sh/posts/diversification-is-overrated/
1•mattredact•58m ago•0 comments