Metformin is also popular in anti-aging circles due to its ability to modulate key cellular aging pathways. It activates AMPK and reduces mTORC1, enhances autophagy, reduces inflammation, and improves mitochondrial function, with studies showing promising, though not yet definitive, effects on increasing healthspan.
I feel it should be made OTC at a low dose of 250 mg.
A few years ago, there was a concern with metformin being contaminated with carcinogenic nitrosamines. I don't know if this ever actually got resolved, also in the context of what people order on their own from abroad.
andsoitis•1h ago
https://pmc.ncbi.nlm.nih.gov/articles/PMC4772077/
OutOfHere•56m ago
A few years ago, there was a concern with metformin being contaminated with carcinogenic nitrosamines. I don't know if this ever actually got resolved, also in the context of what people order on their own from abroad.