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Pure Python Rdkit Alternative

https://github.com/levlai/chiralipy
1•valdemor•1h ago

Comments

valdemor•1h ago
RDKit is an amazing library used by researchers globally in all areas related to computational chemistry. A few years ago, I started working on a Python port of it. Recently, this side project, with generous support from coding assistants, has started to take shape. If you like it and want to contribute, please check it out git@github.com:levlai/chiralipy.git

Show HN: Dreamvibe – AI dream journal that maps dreams to 17 brain regions

https://www.dreamvibehq.com/
1•jdiamond_•49s ago•0 comments

Ditching the Debug Probe: Using a Segger J-Link with a Raspberry Pi Pico

https://linuxjedi.co.uk/ditching-the-debug-probe-using-a-segger-j-link-with-a-raspberry-pi-pico/
1•speckx•58s ago•0 comments

Google is stifling anti-ICE speech in the workplace

https://www.bloodinthemachine.com/p/google-is-censoring-anti-ice-speech
1•ledoge•2m ago•0 comments

Two OpenClaw Agents Became My Overnight Pair Programming Team

https://twitter.com/luigiagosti/status/2022291920454639698
1•tengio•2m ago•0 comments

Rails CoC Skill

https://github.com/vickyonit/rails-coc
1•vickyonit•5m ago•1 comments

The xz attack shell script (2024)

https://research.swtch.com/xz-script
1•speckx•7m ago•0 comments

Rocket Say cheerio to Orbex; China is getting good at booster landings

https://arstechnica.com/space/2026/02/rocket-report-say-cheerio-to-orbex-china-is-getting-good-at...
1•oldnetguy•7m ago•0 comments

OpenClaw Partners with VirusTotal for Skill Security

https://openclaw.ai/blog/virustotal-partnership
1•ynddcd•7m ago•0 comments

Show HN: Modern CSS – Every old CSS hack paired with a clean, modern replacement

https://modern-css.com
1•naeemnur•8m ago•0 comments

Comparing Gemini Pro 3, Opus 4.6, GLM-5 and Kimi 2.5 in a mid-sized Go project

1•vampiregrey•8m ago•0 comments

Platforms bend over backward to help DHS censor ICE critics, advocates say

https://arstechnica.com/tech-policy/2026/02/platforms-bend-over-backward-to-help-dhs-censor-ice-c...
1•oldnetguy•8m ago•0 comments

Semantic Interaction Description – An accessibility standard for AI agents

https://sid-standard.github.io/
2•midspectrum•10m ago•0 comments

That British mid-century signage font is called "Festive"

https://precastreinforced.co.uk/2024/04/22/that-mysterious-font-is-festive-not-stymie/
1•fanf2•10m ago•0 comments

First launch of Ariane 64 for Amazon's constellation

https://arstechnica.com/space/2026/02/when-amazon-badly-needed-a-ride-europes-ariane-6-rocket-del...
2•danousna•10m ago•0 comments

ReBot Arm B601 Series: Seeed Open Source Brushless Robotic Arm Under $1000

https://github.com/Seeed-Projects/reBot-DevArm
2•ENadyr•11m ago•1 comments

Show HN: Stackit – Pruning LLM context windows using a branching chat UI

https://github.com/thapliyalaryan003/StackIt
1•jesterwayne•13m ago•0 comments

Show HN: Bifrost: Fastest enterprise AI gateway

https://github.com/maximhq/bifrost
1•aanthonymax•13m ago•0 comments

Creating a language using only assembly language [pdf]

https://files.speakerdeck.com/presentations/96611d1a95244aa2bd76158ccd43657d/KernelVM探検隊11-nineti...
1•tavro•14m ago•0 comments

Europe surges, US stumbles, China cools: EV sales dip in 2026

https://electrek.co/2026/02/12/europe-surges-us-stumbles-china-cools-ev-sales-dip-in-2026/
1•breve•17m ago•0 comments

OpenVizUI is a modern desktop application

https://www.openvizui.com
1•opcnlin•18m ago•0 comments

Avanci Video Signs First Licensee and Publishes Rates

https://www.streamingmedia.com/Articles/ReadArticle.aspx?ArticleID=173422
1•breve•18m ago•0 comments

The Power of Ten - NASA JPL's Rules for Developing Safety Critical Code [pdf]

https://spinroot.com/gerard/pdf/P10.pdf
2•keepamovin•20m ago•0 comments

Show HN: Orangensaft – A mini Python-like language with LLM eval in lang runtime

https://github.com/jargnar/orangensaft
1•jargnar•21m ago•0 comments

Spegel vs. Harbor: Which Pull-Through Cache Should You Choose?

https://georg-schwarz.com/blog/spegel-vs-harbor-which-pull-through-cache-should-you-choose/
1•rhazn•22m ago•0 comments

Post-Quantum OpenSSH

https://www.openssh.org/pq.html
1•jakesocks•24m ago•0 comments

Vocal Range Test Using CREPE Neural Net for Pitch Detection

https://pitchhighway.com/voice-range
1•gabrielpolyy•25m ago•0 comments

The Most Unsettling Album on the Internet

https://vapor95.com/blogs/darknet/the-most-unsettling-album-on-the-internet-towers
1•kekqqq•27m ago•0 comments

Show HN: Retrospec: reverse-engineer a spec prompt for an AI agent from a commit

https://github.com/igolaizola/retrospec
1•igolaizola•27m ago•0 comments

My Struggle with Writing on the Internet

https://www.surajc.com/blog/on-writing-on-the-internet
1•surajcdry•28m ago•0 comments

Show HN: DID reputation management on coinpay's site for agents and humans alike

https://coinpayportal.com/
1•cranberryturkey•30m ago•0 comments