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Show HN: Jiken – A zero-dependency Python client for real estate transaction API

https://github.com/lfworks/jiken
1•Undecided9226•19s ago•0 comments

Show HN: Compression API for LLM prompts (40-60% token savings, ~5ms overhead)

https://agentready.cloud/hn
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Frontier Model Training Methodologies

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Has Wordle run out of words?

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Show HN: One-line x402 pay-per-request protection for ElysiaJS APIs

https://github.com/codingstark-dev/x402-elysia
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Americans are leaving the US in record numbers

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Long Range E-Bike

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Fix the money, fix the world: Bitcoin as techno-libertarian religion

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I fine-tuned a 14B model to beat GPT-4o at NYT Connections (30% vs. 22.7%)

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Humans Need Not Apply [video]

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Can LLMs SAT?

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Schedule Recurring Tasks in Cowork

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Anthropic is hiring more SWEs than ever, despite AI replacement claims

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Ask HN: What's Your System Prompt?

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The Rabbit Hole of Building a Filesystem Watcher

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Stellantis swings to €22B annual loss

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LMStudio LM Link: Use your local models, remotely

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Mathematicians make a breakthrough on 2k-year-old problem of curves

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2•wglb•15m ago•0 comments

AI and the Dream: Technology in the Service of Humanity

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India's top court bans textbook for referring to judicial corruption

https://www.bbc.com/news/articles/c627l7zexr8o
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2•cmsefton•21m ago•0 comments

You Are Not Called to the Future. You're Called to Now

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1•ObiOnePierogi•21m ago•0 comments
Open in hackernews

Men in their 50s may be aging faster due to toxic 'forever chemicals'

https://www.cnn.com/2026/02/26/health/forever-chemicals-aging-men-wellness
66•jb1991•1h ago

Comments

bonsai_spool•1h ago
This is about a journal article titled "Emerging PFAS contaminants PFNA and PFSA amplify epigenetic aging: sex- and age-stratified risks in an aging population" https://doi.org/10.3389/fragi.2025.1722675 .

The OP says mentions a report from a US Academy but the paper is published in a different journal—this wasn't clear to me at first so I thought I would share the original work.

gryzzly•1h ago
So hard to believe all the skiers and snowboarders were putting PFAS as wax just until couple years ago. Also in Germany, you can buy "permanent baking paper" that is pure PTFE without a problem, which is insane to me.
cannonpr•1h ago
The problem is most data shows PTFE as having significant pyrolysis after 400-500c in reality it starts to break down enough to poison you around 260c. In general though under those temperatures it’s not particularly problematic, ofcourse ideally we should just never make the stuff to begin with as it’s manufacture and its eventual breakdown are both horrible for everyone.
ifwinterco•48m ago
Teflon pans are still legal in every country in the world and used in every restaurant and food preparation industry.

It's basically impossible to avoid this stuff unless you cook all of your meals from scratch and never eat out anywhere

tonyedgecombe•44m ago
> It's basically impossible to avoid this stuff unless you cook all of your meals from scratch and never eat out anywhere

Which is pretty much what you should do if you are concerned about your health at all.

protonbob•43m ago
You don’t have to completely avoid it, reducing exposure is helpful. It’s not hard to get rid of it in your own home where you probably spend most of your time and eat most of your meals.
SkyeCA•36m ago
Teflon is so useful when cooking that I'm going to use it until the moment it gets banned regardless of health impacts.
asimovfan•29m ago
If you mean just a skillet / frying pan, i found that a cast iron pan is much better (for non stick), have been using a €10 one for about three years now. You can ignore all warnings about keeping it oiled etc. They also have glass air fryers now (borosilicate glass, quite durable). You can scrub both with a steel sponge.
hyperbovine•28m ago
Cooking with it at normal fry pan temperatures (350-400f) is safe, this has been repeatedly confirmed in experiments, some not even funded by DuPont. Don’t do crazy things like really high temp searing and don’t use metal utensils that cause the coating to flake off. Also if you’re really concerned ceramic nonstick + oil has come a long way. And I should add the the most nonstick pan I own is actually a properly seasoned carbon steel wok, yes it’s really possible if you know what you’re doing.
chadpaulson•16m ago
I've heard good things about carbon steel. Particularly, nitrided carbon steel. The pans are treated to be non-stick and are safe. It's what Alton Brown, the host of Food Network's Good Eats who also just launched a new cooking show on YouTube, uses.
chadpaulson•25m ago
I use ceramic, but recently learned that nitrided carbon steel pans are the way to go. They are both useful AND safe. Do yourself a favor and invest in one.
bilekas•28m ago
PFOA was used previously, but now it's changed to PTFE, this is supposedly less harmful, but its considered perfectly fine (afaik) as long as the temperatures dont exceed 260°C.. Which at that stage you're probably using the wrong tool.. Maybe some Iron cast skillet or something ?
mrob•10m ago
PFOA is a surfactant that was previously used for emulsion polymerization of PTFE. It's not found in the finished product. It's since been replaced with other less well studied PFAS surfactants that might be less dangerous or might not, which seems to me an example of bad regulation. It would make more sense to regulate disposal of PFOA, which can be done safely with processes such as supercritical water oxidation.

PTFE itself is about as inert as you can get, assuming it's not overheated. If you use PTFE cookwear, I recommend getting an IR thermometer so you can learn how your cooking setup responds and control the temperature properly.

dust42•19m ago
Whenever you see a Youtube video from a restaurant kitchen you can almost be sure to see some pans where the teflon has been scrubbed down to the pure metal. Probably not that healthy...
mrob•5m ago
PTFE is extremely chemically inert. There's possibly some risk from ultra-fine particulates that could be absorbed by the body, but compared to all the other sources of particulate exposure I don't think it's a major problem. I'm more concerned with thermal decomposition, which forms all kinds of mystery chemicals of unknown risk profile. Restaurants love to sear food and I wouldn't be surprised if some of them do it on PTFE cookwear.
hurubaw•1h ago
People born before the 1980 are also of significantly lower IQ up to a 7-8 points due to leaded gas use. The boomers and gen X really did a number on themselves with environmental hazards.
perch56•58m ago
In countries that phased out lead later, even early Millennials faced similar or worse childhood exposure. It’s a global generational story, just with different timelines by country. As a personal example, Romania only phased out leaded gasoline at the end of 2004.
ehnto•31m ago
Some places still allow it in civil aviation too.
MSFT_Edging•26m ago
The US is one.

If you live by a small airport frequented by personal aircraft, you're getting bombarded by lead.

Now just imagine living next to a teaching airport that does aerial laps around the neighborhood.

ricardo81•56m ago
A necessary (?) part of progress IMO. Environmental hazards have been a thing for a lot longer too. Settlements used to be covered in smog due to coal fires for example.

Part of the environmental/emissions argument from developing countries is about past emissions by developed countries. I think it's a fair argument to say given these sacrifices made by past generations in industrialised countries + the benefit of developed cleaner technologies through that industrialisation is an argument against that.

throwup238•52m ago
> Settlements used to be covered in smog due to coal fires for example.

London first tried to ban burning coal within the city in 1306 due to the air quality.

ricardo81•42m ago
That long ago. Surely that helped identify it as a problem even though the science behind it would have been lacking.
jl6•9m ago
I strongly suspect that most of the things we now know to be problematic were also known to be problematic to the ancients, but were thought still to be worth it for their rewards. That’s pretty much where we still are today. Nobody likes breathing pollution, everybody likes modernity.
ricardo81•5m ago
Yes, some things would have just stood to reason in a general respect, even if there wasn't hard science to back it up.
cmrdporcupine•55m ago
Us GenXers didn't do this to ourselves. Boomers (and their parents) did it to us.

I was born '74. Alberta, Canada. I remember people raising a huge stink about "guvmint' interference" when leaded gasoline was banned and when seatbelt use became mandatory. And don't even get started about cigarettes and mandatory separate smoking areas at restaurants etc.

"Liberty" and "freedom" were concepts substantially abused and misapplied throughout the 20th century.

kstenerud•49m ago
They still are. Measles was on the road to being eradicated until 10 years ago.
jazz9k•46m ago
The part you are leaving out is that illegals (now in the millions), living in the US are almost never vaccinated for measles.
analog31•42m ago
Vaccinate them. That's a policy failure.
mmcgaha•32m ago
I have no concern for young generations wanting to blame our age group. The day will come soon that their generation is pointed at for not solving the complex problems of their day. Now if they will show me the same grace when I start a story with "back in my day" we will all get along.
amelius•1h ago
There's this theory that you can dilute the chemicals by doing frequent blood donations.
seethishat•58m ago
I've been told that is beneficial for men with cardiovascular disease too, but I am not sure if that is true.
medi8r•57m ago
Is the leech back?
amelius•46m ago
If you are scared of needles you can have the leech. Donation is generally more useful though.
SkyBelow•8m ago
Did it ever leave? I thought it was still preferred in certain medical procedures. I think something about after reattaching parts of the body it was one of the best options to ensure blood flow in the area, but it has been years since I last read about it.
FrustratedMonky•28m ago
Is there any studies quantifying it? It seems to make sense. Wonder if anybody has measured.
bigtoe416•25m ago
https://pmc.ncbi.nlm.nih.gov/articles/PMC8994130/

“In this randomized clinical trial of 285 firefighters, both blood and plasma donations resulted in significantly lower PFAS levels than observation alone. Plasma donation was the most effective intervention, reducing mean serum perfluorooctane sulfonate levels by 2.9 ng/mL compared with a 1.1-ng/mL reduction with blood donation, a significant difference; similar changes were seen with other PFASs”

ramon156•16m ago
Its kind of funny that a lot of issues I had seemed to not be present when I was donating. Then I took finasteride and now I'm not allowed to donate anymore...
HardwareLust•58m ago
If this were true, would we not see a corresponding drop in life expectancy?
Retric•48m ago
Dead people are easy to see, the issue is trying to differentiate one cause from everything else.

Smoking for example wasn’t believed to be particularly deadly for a surprisingly long time.

9999_points•32m ago
I assume a lot of people 50+ were exposed to a lot more lead and cigarette smoke than younger people.
steveBK123•22m ago
Yes, for those under 30 you have no idea how normalized smoking was right thru the 90s. Restaurants reeked of it, bars more so. A ridiculous percent of men smoked.

I have memories of being quite young sitting in a relatives lap at a baseball game while they smoked. Or my coach in little league smoking a pipe in the dugout filled with 11 year olds.

seidleroni•16m ago
I was explaining this to my elementary school aged kids just a few days ago. We were eating in a restaurant and I told them that when I was their age most restaurants had a smoking and non-smoking section. Of course the smoke did not respect the invisible barrier. The idea that people could just smoke indoors and it was normal really blew their minds.
steveBK123•11m ago
High school boys bathroom was basically a de-facto smoking lounge. It was banned but kids still did it. They occasionally cracked down, but the smell was permanent.

There was also an unwritten understanding that it was preferred the boys went out back to a certain door to smoke outside there instead and wouldn't get in trouble if caught.

OutOfHere•10m ago
Consuming fiber daily, e.g. psyllium husk, is another way to lower some types of PFAS from the body, although not all types of PFAS are going to mix into bile to facilitate this excretion.