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Reversing memory loss via gut-brain communication

https://med.stanford.edu/news/all-news/2026/03/gut-brain-cognitive-decline.html
40•mustaphah•1h ago

Comments

fnord77•23m ago
... in mice. So if any of this held in humans, I think you'd see reversal of old-age memory problems in people treated with antibiotics that kill Parabacteroides goldsteinii.

As far as I know, no such effect has been observed.

And this article claims inflamation from that strain, the NIH claims otherwise: "Parabacteroides goldsteinii is a next-generation probiotic gut bacterium with significant anti-inflammatory and metabolic benefits, often reduced in obese or diseased states. "

vidarh•9m ago
It's possible the specifics are different but that the overall idea still could work for humans. It seems worth at least exploring.
steve1977•23m ago
... in mice.
j45•15m ago
in mice is clearly in the subhead.

The connection between gut-brain has been studied in humans, as well as teh effect of diet and gut bacteria on brain functions.

vidarh•12m ago
And in this case it sounds like the pathway to determining if this has an effect in humans as well might be relatively short given there is a pool of patients receiving vagus nerve stimulation for other things that might provide data.
maxall4•12m ago
I smell bad data. This sounds too good to be true and most studies of this kind have turned out to be false a few years down the line.

Edit: one of many examples: https://www.science.org/content/article/journal-retracts-inf...

theusus•12m ago
Mice mice mice. Tell me when you test on humans

Vela: The True Scale of a Hidden Giant Structure Revealed

https://www.sarao.ac.za/news/vela-the-true-scale-of-a-hidden-giant-structure-revealed/
1•layer8•51s ago•1 comments

Hey HN – Metrx, scorecard for AI agents to understand and optimize their worth

1•ckpark123•1m ago•0 comments

Opennic: Open and community owned DNS root

https://opennic.org/
1•mghackerlady•1m ago•0 comments

Formal foundations of AlphaGeometry: A Lean 4 mechanization

https://zenodo.org/records/18959740
1•AnthonyBordg•2m ago•0 comments

FullStacked, combine Browser and Node.js APIs in a single runtime

https://v1.fullstacked.org
2•cpdabeast•2m ago•1 comments

A simple cryptography native static website deployment toolkit

https://github.com/4pito3pito2pi/unveil-static-site
1•morpheos137•2m ago•1 comments

ReachScan – Static reachability analysis for MCP servers and AI agents

https://github.com/vinmay/reachscan
1•vinmay•3m ago•0 comments

ClawMemory – Git for AI agent memory (forkable memory for AI agents)

1•Brettinhere•4m ago•0 comments

Generation Jones

https://en.wikipedia.org/wiki/Generation_Jones
2•jamesgill•5m ago•0 comments

Dev Cleanup Utility – safe Xcode cleanup for macOS developers

https://apps.apple.com/us/app/dev-cleanup-utility/id1621582261?mt=12
1•kovallux•6m ago•1 comments

Humorous RFCs

https://tangentsoft.com/rfcs/humorous.html
1•tylerdane•7m ago•0 comments

UI Playground — Explore iOS UI components directly on your iPhone

https://www.uiplayground.app/
2•efenande•7m ago•1 comments

Show HN: MoneyOnFIRE – FI date and action plan (v2)

https://www.moneyonfire.com
3•LambdaAndLatte•9m ago•0 comments

Certbot and Let's Encrypt Now Support IP Address Certificates

https://www.eff.org/deeplinks/2026/03/certbot-and-lets-encrypt-now-support-ip-address-certificates
4•speckx•10m ago•0 comments

Nvidia Builds Open Data for AI

https://huggingface.co/blog/nvidia/open-data-for-ai
2•gmays•11m ago•0 comments

ChatGPT Edu feature reveals researchers' project metadata across universities

https://www.fastcompany.com/91507219/chatgpt-edu-researchers-project-metadata-universities-exclusive
2•Cynddl•12m ago•0 comments

Zoloft, Revisited

https://thefrontierpsychiatrists.substack.com/p/zoloft-revisited
2•surprisetalk•12m ago•1 comments

Vertical Integrators (2024)

https://www.notboring.co/p/vertical-integrators
2•surprisetalk•12m ago•0 comments

Place Capability Graphs [video]

https://www.youtube.com/watch?v=JcQX8raHWQE
2•surprisetalk•12m ago•0 comments

Oh, Ambien

https://thefrontierpsychiatrists.substack.com/p/oh-ambien
2•surprisetalk•12m ago•1 comments

Show HN: HCAP – Agent-to-agent (A2A) negotiation

https://www.hcap.dev/
2•krishnamzg•13m ago•0 comments

The Weighted Hotel Minibar Is Wildly Outdated

https://www.insidehook.com/hotels/weighted-minibar-hotel-industry-most-outdated-feature
2•RickJWagner•13m ago•0 comments

Research Links Daily Multivitamins to Slower Biological Aging

https://www.sci.news/medicine/daily-multivitamins-slower-biological-aging-14617.html
2•brandonb•13m ago•0 comments

Kaida Shield – Runtime behavioral monitoring for autonomous AI agents

https://github.com/ajpandit775/kaida-shield
2•panditaditya21•13m ago•1 comments

Shooting at Michigan Shul

https://www.freep.com/story/news/local/michigan/oakland/2026/03/12/temple-israel-shooting-west-bl...
3•marysminefnuf•13m ago•0 comments

The Mag 7 Are Dead. How the Hottest Trade of the Decade Fizzled Out

https://www.barrons.com/articles/stock-movers-1d7440f2?st=eVZYpD
2•RickJWagner•14m ago•0 comments

How we compare model quality in Cursor

https://cursor.com/blog/cursorbench
3•ingve•14m ago•0 comments

Ask HN: Why is my submission not visible if I am not logged in?

2•beepbooptheory•15m ago•3 comments

An Open Letter to Anthropic Leadership

https://claude.ai/public/artifacts/4b1e7231-41fe-4833-be0d-98cdae617320
3•measurablefunc•16m ago•0 comments

The evolution of Mac app window corners

https://lapcatsoftware.com/articles/2026/3/4.html
2•john_alan•17m ago•1 comments