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Show HN: SupplementDEX – The Evidence-Based Supplement Database

https://supplementdex.com/
1•richarlidad•1h ago
Hi this is a work in progress but it works to determine supplement efficacy for 500 conditions at the moment.

Things you can do:

- search for a condition -> find which supplements are effective -> see which studies indicate they are effective -> read individual study summaries

- search for a supplement -> see effectiveness table, dosing, safety, dietary sources, mechanisms of action (+ browse all original sources)

let me know what you think

Demystifying and Improving Lazy Promotion in Cache Eviction [pdf]

https://www.vldb.org/pvldb/vol19/p549-yang.pdf
1•matt_d•10m ago•0 comments

TikTok Investors Set to Pay $10B Fee to Trump Administration

https://www.nytimes.com/2026/03/13/business/tiktok-investors-set-to-pay-10-billion-fee-to-trump-a...
2•defrost•12m ago•0 comments

Optimizing Content for Agents

https://cra.mr/optimizing-content-for-agents/
2•vinhnx•16m ago•0 comments

Lunar Lander ported to the PDP-1

https://hackaday.io/project/204632-lunar-lander-for-the-pdp-1
2•ozymandiax•17m ago•1 comments

How to Build a Successful OpenClaw Startup Without Building Anything

https://twitter.com/SiliconSnark/status/2032641536031121710
1•SaaSasaurus•17m ago•0 comments

Snail Mail Sign-Ups

https://btxx.org/posts/snail-mail-signups/
1•bradley_taunt•25m ago•0 comments

After building agents for 2 years, I stopped using function calling

https://old.reddit.com/r/LocalLLaMA/comments/1rrisqn/i_was_backend_lead_at_manus_after_building_a...
2•gmays•32m ago•0 comments

Skill Issue: Harness Engineering for Coding Agents

https://www.humanlayer.dev/blog/skill-issue-harness-engineering-for-coding-agents
1•vinhnx•33m ago•0 comments

Professor predicts US goes to war with Iran and loses (9 months ago) [video]

https://www.youtube.com/watch?v=7y_hbz6loEo
1•0xbadcafebee•36m ago•0 comments

Rotating home owners boast of 360-degree views and energy benefits

https://www.abc.net.au/news/2026-03-14/rotating-home-owners-boast-of-360-degree-views/106348854
1•defrost•37m ago•0 comments

Show HN: DAAO – Deploy AI agents to your servers via Zero-Trust tunnels

https://github.com/daao-platform/daao
1•dan3093•48m ago•0 comments

The Dirty, Dystopian World of AI Data Centers

https://www.theatlantic.com/magazine/2026/04/ai-data-centers-energy-demands/686064/
1•chrisaycock•48m ago•0 comments

Federal Judge Quashes Justice Department Subpoenas of Fed Chair Jerome Powell

https://www.cnn.com/2026/03/13/politics/fed-chair-jerome-powell-subpoena
4•rickcarlino•50m ago•0 comments

Charles B. McVay III

https://en.wikipedia.org/wiki/Charles_B._McVay_III
2•thunderbong•53m ago•0 comments

Silicon Valley is buzzing about this new idea: AI compute as compensation

https://www.businessinsider.com/ai-compute-compensation-software-engineers-greg-brockman-2026-3
1•pabs3•54m ago•0 comments

Arno's Engram Keyboard Layouts

https://github.com/binarybottle/engram
1•so-cal-schemer•55m ago•1 comments

Rust Shined over Python for My CLI Tool

https://smiling.dev/blog/rust-shined-over-python-for-my-cli-tool/
1•vinhnx•56m ago•0 comments

Companies That Should Exist

https://anastasiagamick.substack.com/p/companies-that-should-exist
1•paulpauper•57m ago•0 comments

How Does AI Distribute the Pie? Large Language Models and the Ultimatum Game

https://www.nber.org/papers/w34919
1•paulpauper•57m ago•0 comments

Buying Back Our Slack

https://www.seeingthesystem.com/p/buying-back-our-slack
1•paulpauper•58m ago•0 comments

Agentic AI: Workflows vs. Agents

https://www.youtube.com/watch?v=Qd6anWv0mv0
1•Brysonbw•58m ago•0 comments

MacBook Neo Teardown [video]

https://www.youtube.com/watch?v=PbPCGqoBB4Y
1•Lwrless•58m ago•0 comments

Trump now Selling National Security Briefing Membership

https://www.cnn.com/2026/03/13/politics/trump-fundraise-email-soldier
10•mandeepj•1h ago•1 comments

Big tech engineers need big egos

https://www.seangoedecke.com/big-tech-needs-big-egos/
1•jnord•1h ago•0 comments

Void – Ship Vite apps at warp speed

https://void.cloud
1•todotask2•1h ago•0 comments

1997 Kyl–Bingaman Amendment prohibits high res satellite imagery of Israel

https://en.wikipedia.org/wiki/Kyl%E2%80%93Bingaman_Amendment
5•spaghetdefects•1h ago•0 comments

Show HN: Paw-proxy – Named HTTPS domains for every local dev server

https://alexcatdad.github.io/paw-proxy/
1•alex_tc•1h ago•0 comments

Show HN: What agentic collaborative pentesting looks like

https://www.youtube.com/watch?v=PU5BicXMiio
1•integsec•1h ago•0 comments

JPEG Compression

https://www.sophielwang.com/blog/jpeg
3•vinhnx•1h ago•0 comments

Want to hack your body with peptides? If only the science agreed

https://www.economist.com/science-and-technology/2026/03/11/want-to-hack-your-body-with-peptides-...
2•andsoitis•1h ago•0 comments