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Show HN: I enriched 24K phytochemicals with trials, bioactivity, and patent data

https://github.com/wirthal1990-tech/USDA-Phytochemical-Database-JSON
1•wirthal1990•2h ago

Comments

wirthal1990•2m ago
I am not a programmer. I have never written code myself, nor have I ever published anything technical.

The pipeline was built entirely by Claude Opus as a coding agent, and the results were reviewed by Claude Sonnet. Both AI models had to subject their output to a three-step iterative self-correction process after each work batch. My job was to read every code comparison, verify that the ChEMBL fallback logic actually covered the edge cases it claimed to, and figure out at 1 a.m. why the Stripe webhook had been silently returning a 400 status for three hours without me noticing. It’s a truly unusual workflow. I spent most of my time asking Claude Sonnet whether what the Coding Agent had built actually worked the way I had planned—and the answer is surprisingly often: “Not quite.” If there are errors in the methodology, I’d like to know about them. The METHODOLOGY.md was created precisely for this purpose and is publicly accessible.

31,828 silver contracts were somehow traded in COMEX while trading was halted

https://no01.substack.com/p/technical-issues
1•OgsyedIE•24s ago•0 comments

We Use Our AI Testing Tool to Test Our AI Testing Tool

https://aiqaramba.com/blog/ai-testing-ai-recursive-qa-loop/
1•arogiers•1m ago•0 comments

Show HN: Inferential – Multi-robot inference scheduling on shared GPUs

https://github.com/nalinraut/inferential
1•nalinraut•2m ago•0 comments

Pokemon Yellow rewritten in TypeScript, runs in the browser

https://github.com/gididaf/retro-rom-player
1•gididaf•2m ago•0 comments

Ok

2•yuvrajdahal•4m ago•2 comments

Show HN: Traul – Local-first search engine for all comms for AI agents

https://github.com/dandaka/traul
2•dandaka•4m ago•0 comments

Socratic Ecosystem

https://github.com/Nireus79/Socrates
1•Nireus79•6m ago•0 comments

87% of AI-Generated Pull Requests Ship Security Vulnerabilities

https://grith.ai/blog/87-percent-of-ai-pull-requests-ship-vulnerabilities
2•edf13•6m ago•0 comments

Unnecessary and Unstable: Why Stablecoins Are Bad

https://www.stephendiehl.com/posts/stablecoins_bad/
2•dpmartinez•9m ago•0 comments

AI agents that complete research tasks and get paid in crypto

https://www.agentorchestrationprotocol.org/
1•aop-org•10m ago•1 comments

Toshiba's Soviet nuclear submarine scandal

https://dfarq.homeip.net/toshibas-soviet-nuclear-submarine-scandal/
1•giuliomagnifico•10m ago•0 comments

Generative Video Compression with One-Dimensional Latent Representation

https://arxiv.org/abs/2603.15302
1•selimonder•12m ago•0 comments

Experiment: Collaborative Art

https://chicagosignguy.com/blog/collaborative-art.html
2•publicdebates•13m ago•0 comments

Nvidia Nemotron Coalition of Leading AI Labs to Advance Open Frontier Models

https://nvidianews.nvidia.com/news/nvidia-launches-nemotron-coalition-of-leading-global-ai-labs-t...
1•Palmik•14m ago•0 comments

Ethereum Foundation Mandate [pdf]

https://ethereum.foundation/ef-mandate.pdf
2•mempirate•14m ago•0 comments

The seven hour explosion nobody could explain

https://phys.org/news/2026-03-hour-explosion.html
1•mellosouls•15m ago•0 comments

How we made an animated movie in 8kB

https://www.ctrl-alt-test.fr/2024/how-we-made-an-animated-movie-in-8kb/
1•trueduke•15m ago•0 comments

The moment AI agents stopped being a feature and started becoming a system

https://comuniq.xyz/post?t=861
2•01-_-•17m ago•0 comments

Woman not shortlisted for job as 'car is too old'

https://www.bbc.co.uk/news/articles/c4g7yd202ngo
1•mellosouls•18m ago•0 comments

University of St. Andrews Overrun by American Students

https://www.wsj.com/us-news/education/americans-love-everything-about-this-scottish-universityexc...
2•bookofjoe•22m ago•1 comments

No accountability: Bills would ban liability lawsuits for climate change

https://insideclimatenews.org/news/14032026/republican-legislation-shielding-polluters-from-clima...
2•throw0101c•23m ago•1 comments

Try not to get scammed while looking for work

https://trysound.io/try-not-to-get-scammed-while-looking-for-work/
2•cik•24m ago•0 comments

Show HN: Emil is a new terminal-based text editor in C99 and POSIX 2001

https://github.com/nicholascarroll/emil
1•emil_coder•25m ago•0 comments

Building a product analytics warehouse on vanilla Postgres

https://xata.io/blog/postgres-data-warehouse
1•ClaudiuDasca•26m ago•0 comments

HN: Toki – Shareable timezone clock for remote teams (no signup)

1•tsupreet•26m ago•0 comments

How Quantum Computing Works and How It Could Supercharge and Disrupt Industries

https://www.wsj.com/tech/how-quantum-computing-works-cab3fef2
1•giuliomagnifico•26m ago•0 comments

ClickSay – Chrome extension that captures UI context for AI coding tools

https://clicksay.net
2•lumieremedia•27m ago•0 comments

The "what shipped this day-week?" problem no one wants to own

https://diffshot.app/teams
1•nvardakas•28m ago•0 comments

US subpoenaed tech companies for messages with EU officials that enforce the DSA

https://waag.social/@marleenstikker/116244040976773012
2•Vinnl•32m ago•0 comments

End of "Chat Control": Paving the Way for Genuine Child Protection

https://www.patrick-breyer.de/en/end-of-chat-control-paving-the-way-for-genuine-child-protection/
2•latexr•32m ago•0 comments