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Show HN: Clinical Trial Finder and Ranker

https://clifton-topaz.vercel.app/
1•notwopr•1h ago
hey all. just trying to get the word out about this app i made. It's called Clifton. it's helped me out a lot and so thinking it could help others too. let me know what you think and if you know anyone who might find it useful, please share!

it's free and open source (https://github.com/notwopr/clifton)

my mom has alzheimers and vascular dementia and i used to keep this incredibly complicated spreadsheet just to keep track of what clinical trials i already reviewed and which ones would actually fit our needs. it was honestly such a pain to maintain and update every few weeks.

i wanted a way to find trials where there was a low chance of a placebo, stuff that was actually nearby, and trials that didn't have super invasive diagnostic testing... reading through eligibility criteria on clinicaltrials.gov for hours just to find out a trial is a 4 hour drive away or has a 50% placebo rate is exhausting.

so i decided to just build my own thing.

hope it helps other people out there too.

it's free, but im hoping the AI searches dont get too out of control because i cant really afford too much. but if anyone knows how i can get google to sponsor this site PLEASE let me know (it uses gemini)

Tell HN: Microsoft365 "Convert to Paid" checkout silently default to 25 licenses

2•davidstarkjava•2m ago•0 comments

Show HN: Passport Globe (See where your passport takes you)

https://hariharan.uno/globe
1•hariharan_uno•11m ago•0 comments

Show HN: TMA1 – Local-first observability for LLM agents

https://tma1.ai/
1•killme2008•12m ago•0 comments

Show HN: Yeet – Throw AI tasks at hardware and walk away (Nomad and OpenShell)

https://github.com/wan0net/yeet
1•wan0net•12m ago•0 comments

Phase Transitions and Computation

https://theory.org/complexity/cdpt/html/node5.html
1•downboots•16m ago•0 comments

Show HN: Banish: A declarative framework for rule-based state machines in Rust

https://github.com/LoganFlaherty/banish/releases/tag/v1.3.0
1•LoganFlaherty•17m ago•0 comments

Bitcoin mining difficulty drops 7.8% as miner exodus accelerates amid AI pivot

https://www.theblock.co/post/394579/bitcoin-mining-difficulty-drops-7-8-as-miner-exodus-accelerat...
2•adrianwaj•17m ago•1 comments

Review: Why Evolution Is True

https://ncse.ngo/review-why-evolution-true
1•akbarnama•20m ago•0 comments

We Read What Delve Ships to the Browser

https://security.redeux.ai/research/delve-compliance-posture
1•chasewarren•30m ago•0 comments

Isometric exercise: The most efficient fitness regime?

https://www.bbc.com/future/article/20260319-isometric-exercise-the-most-efficient-fitness-regime
1•akbarnama•34m ago•0 comments

A Rant about Resolutions

https://blog.brixit.nl/rant-about-resolutions/
1•vinhnx•35m ago•0 comments

Is Simple Good?

https://darth.games/posts/is-simple-good/
1•vinhnx•36m ago•0 comments

Delve Accused of Fraud

https://techcrunch.com/2026/03/21/delve-accused-of-misleading-customers-with-fake-compliance/
3•zlu•40m ago•0 comments

Sashiko: AI code review system for the Linux kernel spots bugs humans miss

https://www.theregister.com/2026/03/20/sashiko_code_review_linux/
2•maxloh•41m ago•0 comments

AI Disrupts Talent Evaluation Before It Disrupts Talent

https://substack.com/home/post/p-191732116
2•cactaceae•43m ago•0 comments

A Reason to Ditch Jira: AI Agents

https://age-of-product.com/jira-ai-agents/
1•swolpers•44m ago•0 comments

Show HN:Entroly – Compress codebase context for LLMs by 78% using Rust

https://github.com/juyterman1000/entroly
1•savetokens•46m ago•0 comments

The History and Business of Formula 1

https://www.acquired.fm/episodes/formula-1
1•vismit2000•46m ago•0 comments

Why Even Smart People Believe AI Is Thinking

https://www.wsj.com/tech/ai/ai-tools-sentience-b98fc6e6
1•1vuio0pswjnm7•48m ago•0 comments

OpenAI to introduce ads to all ChatGPT free and Go users in US

https://www.reuters.com/business/media-telecom/openai-expand-ads-chatgpt-all-free-low-cost-users-...
1•1vuio0pswjnm7•56m ago•0 comments

Anthropic just shipped an OpenClaw killer

https://venturebeat.com/orchestration/anthropic-just-shipped-an-openclaw-killer-called-claude-cod...
3•qwertmax•57m ago•1 comments

Not Even Elon Musk Can Get Nvidia Stock Moving

https://www.barrons.com/articles/nvidia-stock-price-musk-ai-1a20fbaf?
1•1vuio0pswjnm7•1h ago•0 comments

David Botstein, RIP

https://www.nytimes.com/2026/03/20/science/david-botstein-dead.html
2•paulpauper•1h ago•0 comments

My Time with Jürgen Habermas, Europe's 'Last Intellectual'

https://www.politico.com/news/magazine/2026/03/20/karp-habermas-remembrance-00838398
1•paulpauper•1h ago•0 comments

The M4 Apple Neural Engine, Part 3: Training

https://maderix.substack.com/p/inside-the-m4-apple-neural-engine-c8b
1•wslh•1h ago•0 comments

Did Delve (Compliance) Commit Securities Fraud?

1•ManuelSuarez•1h ago•0 comments

Show HN: TempMail Mail – Disposable email with per-domain blocking

https://tempmailmail.com
1•Sharanxxxx•1h ago•0 comments

"Surveillance Camera Man" Provokes Questions About Recording in Public (2013)

https://archive.blogs.harvard.edu/internetmonitor/2013/07/10/surveillance-camera-man-draws-ire-pr...
3•greyface-•1h ago•0 comments

AWS Kiro accounts suspended en masse – AWS flagging fraud detection issues

https://github.com/kirodotdev/Kiro/issues
1•huey77•1h ago•1 comments

Show HN: Agent skill for Excalidraw diagrams with animation and image

1•muthuishere•1h ago•0 comments