Of course, when you're setting up your OS initially, it will ask you questions about language and keyboard layout. I suspect most people don't switch keyboards after install, and of those who do, the most common case is another keyboard with a compatible layout.

The most likely reason it would be a problem then would be that some Raspberry Pi images have defaulted to British English keyboard layouts. Otherwise you may be sailing through life unburdened by what can be a major pain to anyone anywhere else in the world, like a resident of Arizona wondering why the rest of the world keeps messing with their clocks.

Edit: perhaps you're making the case that the user doesn't choose which key. This is true—but the important point is that one of the two parties did choose the specific key to press.