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What's the deal with Alzheimer's disease and amyloid?

https://arstechnica.com/science/2026/04/whats-the-deal-with-alzheimers-disease-and-amyloid/
3•quapster•2h ago

Comments

fnord77•1h ago
It's disheartening is there's been almost zero progress in treating this terrible disease. Unlike many other diseases like cancer and autoimmune diseases where tremendous progress has been made.

Playonsnow.com – Play HTML5 Games for Free

https://playonsnow.com/
1•jackpste•1m ago•1 comments

Making dark mode play nicely with bfcache

https://guilhermesimoes.github.io/blog/making-dark-mode-work-with-bfcache
1•glitchdout•2m ago•0 comments

Wall Street's Elite Team of Coffee Tasters Who Keep the Global Market Running

https://www.wsj.com/lifestyle/careers/wall-street-has-an-elite-coffee-tasting-force-its-strugglin...
2•thm•3m ago•0 comments

Sustaining creative aliveness while working a full time job

https://www.startingfromnix.com/p/sustaining-creative-aliveness-while
1•jger15•3m ago•0 comments

Stopping the Meta AI director's "OpenClaw failure with an out-of-band killswitch

https://highflame.com/blogs/why-metas-ai-alignment-director-couldnt-stop-her-own-agent--and-how-t...
2•jalbrethsen•3m ago•1 comments

Waymo Opens to Everyone in Miami and Orlando

https://waymo.com/blog/2026/04/floridas-new-way-to-ride/
1•xnx•3m ago•0 comments

Unified MCP Server for Jira and Confluence Server/DC Behind Citrix NetScaler SSO

https://github.com/paul-pfeiffer/atlassian-netscaler-mcp
1•paulpfe•4m ago•1 comments

Urgentry: Ultra-efficient, self-hostable drop in replacement for Sentry

https://urgentry.com/
1•handfuloflight•4m ago•0 comments

Planar maps: an interaction paradigm for graphic design (1989) [pdf]

https://www.lri.fr/~mbl/FundHCI/papers/Baudelaire-CHI89.pdf
1•tliltocatl•5m ago•1 comments

HuggingFace launches pre-compiled machine learning kernels repository

https://huggingface.co/changelog/kernels
1•embedding-shape•5m ago•1 comments

Battery storage is now cheap enough to unleash India's full solar potential

https://ember-energy.org/latest-insights/battery-storage-is-now-cheap-enough-to-unleash-indias-fu...
1•xbmcuser•5m ago•0 comments

Oracle taps Bloom for 2.8 GW of fuel cells to keep datacenter binge going

https://www.theregister.com/2026/04/14/oracle_bloom_fuel_cells/
1•Bender•5m ago•0 comments

Use Claude, ChatGPT, or MiniMax Subscriptions in Cursor

https://open-vsx.org/extension/orchidfiles/ungate
1•theorchid•6m ago•0 comments

Show HN: Fakecloud – Free, open-source AWS emulator

https://github.com/faiscadev/fakecloud
2•lucas_vieira•8m ago•0 comments

Show HN: Multi-Agent Orchestration on Top of Vercel AI SDK (TypeScript, Next.js)

https://github.com/JackChen-me/open-multi-agent/tree/main/examples/with-vercel-ai-sdk
1•JackChen_me•8m ago•0 comments

I ran 90 queries through 8 AI models. 86% of findings were unique to one

https://parallect.ai/blog/divergence-study
3•primeobsession•8m ago•0 comments

Manage VS Code Extensions Like Packages with Posit Package Manager

https://posit.co/blog/manage-vs-code-extensions-like-packages-with-posit-package-manager-2026-04-0
1•nodivbyzero•9m ago•0 comments

Autoresearch Applied at Shopify

https://shopify.engineering/autoresearch
2•austinbaggio•11m ago•1 comments

I Did My Taxes with Claude

https://doempke.com/taxes-with-claude/
2•robk•11m ago•0 comments

I got my React SPA to 95/100/100/100 on mobile PageSpeed

https://sudorank.com/blog/pagespeed-optimization/
1•iambala•12m ago•0 comments

Gemini 3.1 Flash TTS – with directed prompts

https://simonwillison.net/2026/Apr/15/gemini-31-flash-tts/
3•aanet•13m ago•1 comments

Agents Can Act.Only You Should Authorize

https://github.com/nametaginc/nametag-a2h
1•manish198903•13m ago•0 comments

What it's like to house-hunt in Silicon Valley (2015)

https://www.washingtonpost.com/business/economy/what-its-like-to-house-hunt-in-silicon-valley-the...
1•downbad_•14m ago•1 comments

Attention IS NOT all u need

https://github.com/Elgoghel/hwta-circuits/blob/main/README.md
1•Elgoghel•14m ago•0 comments

Show HN: Hatch: customise agents once, generate all the files

https://github.com/matryer/hatch
1•matryer•14m ago•0 comments

Google Broke Its Promise to Me. Now ICE Has My Data

https://www.eff.org/deeplinks/2026/04/google-broke-its-promise-me-now-ice-has-my-data
3•Brajeshwar•16m ago•0 comments

Spotted a bear lately? You're not alone–why sightings are on the rise

https://cssh.northeastern.edu/spotted-a-bear-lately-youre-not-alone-why-sightings-are-on-the-rise/
1•PaulHoule•16m ago•0 comments

Show HN Deskdrop: An Android Keyboard with Local AI Support (Ollama, LM Studio)

https://github.com/SvReenen/Deskdrop
1•SvReenen•16m ago•0 comments

Snap Is Laying Off 16% of Full-Time Staff as It Embraces A.I

https://www.nytimes.com/2026/04/15/business/snap-layoffs-snapchat.html
4•xnx•17m ago•0 comments

Lyra 2.0: Explorable Generative 3D Worlds

https://arxiv.org/abs/2604.13036
1•aanet•18m ago•1 comments