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How I sequenced my genome at home

https://twitter.com/sethshowes/status/2045782975380406623
5•Finbarr•1h ago

Comments

Bender•1h ago
Once a person has their own DNA how do they analyze it to find known attributes like genetic dysfunctions, diseases and other characteristics without sharing said DNA with a third party?

This X post ultimately links to iwantosequencemygenomeathome.com [1]

[1] - https://iwantosequencemygenomeathome.com/

rolph•1h ago
nanopore sequencing:

https://pmc.ncbi.nlm.nih.gov/articles/PMC9966803/

https://en.wikipedia.org/wiki/Nanopore_sequencing

https://pubs.acs.org/doi/10.1021/acs.langmuir.4c04961

BTW this tech can be used for more than sequencing, if you can arbitrarily pushmepullya the strand back and forth through the pore, or join the strand ends and cycle a hoop through the pore you can read, snip, splice, and continue, until you have a customized strand.

"Now I Have the Full Picture"

https://taoofmac.com/space/notes/2026/04/19/1400
1•rcarmo•2m ago•0 comments

They Went Abroad to Save Money. Moving Back Seems Unaffordable

https://www.nytimes.com/2026/04/19/business/americans-abroad-cheaper-living-costs.html
1•mikhael•4m ago•0 comments

The Unsuitability of English (2015)

https://www.chronicle.com/blogs/linguafranca/the-unsuitability-of-english
1•downbad_•5m ago•1 comments

A Chinese Android just ran a half-marathon faster than any human

https://www.cnn.com/2026/04/19/china/china-robot-half-marathon-intl-hnk
4•Bender•10m ago•1 comments

Show HN: Faceoff – A terminal UI for following NHL games

https://www.vincentgregoire.com/faceoff/
3•vcf•11m ago•0 comments

Show HN: A drop-in, open-source replacement for YouTube embed iframes

https://embedlite.com/
1•corentin88•11m ago•0 comments

The Bromine Chokepoint: How Strife Could Halt Production of World’s Memory Chips

https://warontherocks.com/cogs-of-war/the-bromine-chokepoint-how-strife-in-the-middle-east-could-...
3•crescit_eundo•11m ago•0 comments

Air Force Recruits Most New Airmen Since 2004, Making Goal Early

https://www.airandspaceforces.com/active-air-force-hits-recruiting-goal-early-2026/
2•Bender•12m ago•0 comments

Thermometry of simulated Bose–Einstein condensates using machine learning

https://iopscience.iop.org/article/10.1088/2632-2153/ae4f4f
1•opnac•13m ago•0 comments

Sam Altman reportedly targeted in second attack

https://www.theverge.com/ai-artificial-intelligence/910890/openai-sam-altman-second-home-attack-s...
2•GaryBluto•13m ago•0 comments

Make flipbooks from browser sessions, videos and documents

https://flipbook.browserbox.io
1•keepamovin•14m ago•0 comments

Recent advances push Big Tech closer to the Q-Day danger zone

https://arstechnica.com/security/2026/04/while-some-big-tech-players-accelerate-pqc-readiness-oth...
1•Bender•15m ago•0 comments

Show HN: Alodb – I got tired of pasting my Postgres schema into ChatGPT

https://alodb.com
1•eyvzov•17m ago•1 comments

When old HTML5 dreams become reality – field generator in a nutshell

https://rogmash.neocities.org/AuroraCore
1•rogmash•18m ago•2 comments

MCPs are the music of AI Agents. We built the player

https://github.com/vinkius-labs/mcp-explorer
1•renatomarinho•19m ago•0 comments

Why North Koreans Don't Revolt? (and Probably Never Will) [video]

https://www.youtube.com/watch?v=CtgJzLx7y04
1•lisper•19m ago•0 comments

A frictionless, self-hosted e-book sync between Kindle, Android, and KOReader

https://philwornath.com/garden/self-hosted-ebook-sync-koreader
1•ph1lw•19m ago•0 comments

How to Break a Terroristleigh Dickinson University

https://www.youtube.com/watch?v=JaSp20sjc10
1•tukunjil•20m ago•1 comments

Alex Karp is a pathetic toddler

https://www.hamiltonnolan.com/p/grievance-poisoning-in-the-first
2•blackcoffeerain•21m ago•0 comments

Babies Born from Dead Parents Will Increase with New Tech

https://www.404media.co/babies-born-from-dead-parents-will-increase-with-new-tech-are-we-ready/
1•Brajeshwar•22m ago•0 comments

Multi-agent systems: Frameworks and step-by-step tutorial

https://blog.n8n.io/multi-agent-systems/
1•onchainintel•24m ago•0 comments

Dario – local proxy to keep Claude Pro/Max working with any client

https://github.com/askalf/dario
1•askalf•24m ago•1 comments

The Dangers of Reusing Protobuf Definitions: Critical Code Exec in Protobuf.js

https://www.endorlabs.com/learn/the-dangers-of-reusing-protobuf-definitions-critical-code-executi...
1•gnabgib•25m ago•0 comments

The Imperative of Mastering Writing and Coding in the Age of Automation

https://fodysoft.com/blog/learn-coding/
1•osdotsystem•27m ago•1 comments

Software Driven Drive Lights

https://bumblingelectron.blogspot.com/2026/04/creating-drive-lights-on-gpio-linux-only.html
1•mainmeister•28m ago•0 comments

Model Council

https://github.com/bruce249/Model_Council
1•vignesh_146•29m ago•1 comments

SQLite prefixes its temp files with `etilqs_`

https://avi.im/blag/2026/etilqs/
1•birdculture•33m ago•0 comments

Some secret management belongs in your HTTP proxy

https://blog.exe.dev/http-proxy-secrets
2•tosh•36m ago•0 comments

Show HN: Infrawise Azure Cloud Optimization

https://infrawiseai.com
1•pdroid12•36m ago•0 comments

Show HN: Bridge the gap between AI code/app generation and human understanding

https://sourcebridge.ai
1•Craze0•37m ago•0 comments