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Bad brains will bottleneck connectomics

https://preservinghope.substack.com/p/bad-brains-will-bottleneck-connectomics
2•arielzj•1h ago

Comments

arielzj•1h ago
Connectomics — mapping every neural connection in a brain — is advancing fast enough that a complete human brain map may be feasible within a decade or two. But there's a problem nobody talks about: human brains donated to science are preserved hours or days after death, by which point the tissue is too degraded for the long-range neuron tracing a full connectome requires. The unexpected fix may come from preservation/biostasis/cryonics organizations preserving brains of assisted-dying patients within minutes of death.

I Moved My Digital Stack to Europe

https://monokai.com/articles/how-i-moved-my-digital-stack-to-europe/
1•monokai_nl•25s ago•1 comments

Texas Instruments made a new flagship graphing calculator: the TI-84 Evo

https://www.engadget.com/mobile/texas-instruments-made-a-new-flagship-graphing-calculator-the-ti-...
1•HiroProtagonist•28s ago•0 comments

Linus's Law, but Vulnerabilities

https://opensourcesecurity.io/2026/04-linus-law-vulns/
1•milkglass•1m ago•0 comments

The Missing Piece: A Self-Custody Wallet for AI Agents

https://pckt.blog/b/krzysu/the-missing-piece-a-self-custody-wallet-for-ai-agents-zc1vdj6
1•krzysu•2m ago•0 comments

LaDiR: Latent Diffusion Enhances LLMs for Text Reasoning

https://machinelearning.apple.com/research/ladir
1•chmaynard•3m ago•0 comments

Show HN: NeonD – self-hosted Postgres Platform with branching, PITR and backups

https://github.com/matisiekpl/neond/
1•matisiekpl•3m ago•1 comments

Meta isn't doing enough to keep kids off Facebook and Instagram, rules EU

https://www.theverge.com/tech/920313/meta-facebook-instagram-eu-dsa-age-verification
1•Brajeshwar•5m ago•0 comments

Mini Shai-Hulud: Bun Payloads Hit SAP NPM Packages

https://www.stepsecurity.io/blog/a-mini-shai-hulud-has-appeared
1•likhith190•5m ago•0 comments

Claude for Word

https://claude.com/claude-for-word
1•taspeotis•5m ago•0 comments

Show HN: Adblock-rust Manager – Firefox extension to enable the Brave ad blocker

https://github.com/electricant/adblock-rust-manager
1•electricant•5m ago•0 comments

Nobody Here: The Story of Vaporwave [video]

https://www.youtube.com/watch?v=6kNqw7UdENg
1•phaser•6m ago•0 comments

Epic Games Wins Reversal of Stay in App Store Fee Legal Battle

https://www.macrumors.com/2026/04/29/epic-games-wins-reversal-app-store-fee-battle/
1•tosh•6m ago•0 comments

I scanned 16 open-source AI agent repos – 76% of tool calls had zero guards

https://github.com/Diplomat-ai/diplomat-agent
1•jguarnelli•6m ago•0 comments

Brazil's AI adoption boom in public numbers: what IBGE, Bain and Gartner say

https://dataconcierge.dev/en/blog/brazil-ai-adoption-public-numbers
1•altruisticlove•7m ago•0 comments

Show HN: Filling PDF forms with AI using client-side tool calling

https://copilot.simplepdf.com/?share=a7d00ad073c75a75d493228e6ff7b11eb3f2d945b6175913e87898ec96ca...
3•nip•8m ago•0 comments

Anodized – catch Rust runtime bugs at compile time

https://docs.rs/anodized/latest/anodized/
2•satvikpendem•11m ago•0 comments

DARS – Field and Division‑Break Demo

https://rogmash.neocities.org/singularity
1•rogmash•11m ago•0 comments

Show HN: I built a 2nd-order PyTorch optimizer for LLMs that runs on 16GB GPUs

2•dnosoz•11m ago•2 comments

Coffee with a splash of physics: how to make the most out of your brew

https://physicsworld.com/a/coffee-with-a-splash-of-physics-how-to-make-the-most-out-of-your-brew/
2•sohkamyung•11m ago•0 comments

Building AI Agents in Python with Pydantic AI

https://machinelearningmastery.com/building-ai-agents-in-python-with-pydantic-ai/
1•eigenBasis•12m ago•0 comments

OAuth Scopes Explained (2025)

https://fusionauth.io/blog/how-to-design-oauth-scopes
1•mooreds•12m ago•0 comments

Re: Starred – A weekly email with 3 GitHub repos you starred and forgot

https://restarred.dev
1•alepricedev•12m ago•0 comments

96% of GitHub repos have high severity issues in their Action workflows

https://pin-gh-actions.kammel.dev/zizmor
2•datosh•12m ago•1 comments

It Just Has to Work

https://michaelheap.com/it-just-has-to-work/
1•mooreds•12m ago•0 comments

Google's Liz Reid on Who Will Own Search in a World of AI [video]

https://www.youtube.com/watch?v=DP8qe2Qo2-s
1•mooreds•13m ago•0 comments

Buckets and objects are not enough

https://sagi.org/posts/buckets-and-objects-are-not-enough/
1•sagiba•13m ago•0 comments

Versioned, portable LLM prompts as a spec – not a framework

https://promptpack.org/docs/rfcs/workflow-composition/
1•chaholl•15m ago•0 comments

Dtdss, Dtdss Algorithm, Dtdss Soft Sensing, Dtdss Sensor

https://arxiv.org/abs/2604.15352
1•iopoer•17m ago•0 comments

Is this the screenshot tool Linux users want?

https://apexshot.org
1•codegoddy•18m ago•0 comments

The U.S. Wants to Ban China's High-Tech Cars, They're Already Here in El Paso

https://www.wsj.com/business/autos/chinese-cars-byd-geely-u-s-mexico-be0dea28
2•impish9208•20m ago•1 comments