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Craig Venter has died

https://www.jcvi.org/media-center/j-craig-venter-genomics-pioneer-and-founder-jcvi-and-diploid-genomics-inc-dies-79
101•rdl•1h ago

Comments

rdl•1h ago
He was pretty shockingly an entrepreneur and inventor in all the best ways,’in a field dominated by very cautious scientists (who are great too, but who likely never would have gotten the genome sequenced within 10-20 years of when he did it). It was basically the Apollo Project in a field which was more like 1980s NASA in culture.
dnautics•1h ago
iiuc it was hamilton smith who insisted that shotgun sequencing would work. the nih side insisted on primer walking until celera started assembling the genome so rapidly that the nih had to get in on shotgun too
acmj•20m ago
No, at initial release, the human genome from the NIH side was done by bac-to-bac, not by shotgun.
echelon•1h ago
> in a field dominated by very cautious scientists (who are great too, but who likely never would have gotten the genome sequenced within 10-20 years of when he did it).

I did a bio undergrad and one of my professors was involved. She was adamant that the Human Genome Project finished ahead of Celera and that the HGP published reference data that Venter and team fundamentally relied upon to even have their shotgun approach work.

dnautics•1h ago
i worked for ham smith and my understanding through him is that both sides relied on data that the other produced.
apitman•1h ago
Craig Venter was famously involved in the Human Genome Project. He announced the first draft of the human genome alongside President Clinton and Francis Collins.
dnautics•1h ago
i believe he also was the human genome project, he arranged to have one of the samples be him
jltsiren•45m ago
Craig Venter had his genome sequenced in 2007. It was the first individual human genome that was sequenced and released publicly.

The human reference genome is ~70% from a man with African and European ancestry who lived somewhere around Buffalo, NY. Most of the rest is from ~20 other individuals in the same area. They were supposed to sequence the samples more evenly, but apparently there were some technical reasons that made them prioritize a single sample.

moralestapia•45m ago
Yes, his was the first complete genome ever sequenced (by a private entity).
schoen•26m ago
This reminds me of the interesting fact that

> Linnaeus is designated as the type specimen for the human species, Homo sapiens.

https://en.wikipedia.org/wiki/Carl_Linnaeus

acmj•26m ago
You are confused by the human genome project vs the celera genome project. No, the human genome project didn't include his sample.
alex1138•1h ago
Sad news. This video https://www.youtube.com/watch?v=3E25jgPgmzk was interesting back in the day
koeng•1h ago
I met Craig about a year ago or so at a synthetic biology conference. Even though his institute was the one which created the first synthetic cell, he pretty much just talked about how disappointing it was that we couldn't engineer the ribosome more. Was a funny memory :) guess you always want more once you do something great.
dyauspitr•1h ago
Oh no! I did an internship at his lab when I went to UCSD. RIP.
kingsleyopara•54m ago
I went to a talk of his once and discovered that I also have aphantasia. Seemed like a genuinely nice guy the little I interacted with him. RIP
jfengel•35m ago
That's unexpected. He was only 80, and as I understand it still working.

My his memory be a blessing.

jwilliams•25m ago
Sad news. I met Craig very briefly at a conference probably a decade back. I pretty much was a self-study in genetics at the time... so let's just say I wasn't in Craig's league. Despite this he was very engaged and took the time for a very thoughtful chat.
timcobb•21m ago
RIP Craig Venter.

I remember being in 5th grade and hearing about the Human Genome Project. It was presented as a radical undertaking. 30 years later, look how far we've come. Just the other day I was reading about the UK Biobank leaks (https://news.ycombinator.com/item?id=47875843), and it was mentioned that some large number of complete human genomes were leaking out. And I thought wow, back in the day people thought Craig Venter was out there.

Thank you Craig Venter!

gwerbret•20m ago
Somewhat ironically, he'd spent the last years of his life working on prolonging life [1], and was selling a $25,000 "proactive healthcare service" consultation to anyone who could afford it [2].

1: The company's website, humanlongevity dot com, seems to have been compromised, and as "captcha" will try to have you install a Trojan. So here's the Wikipedia page instead: https://en.wikipedia.org/wiki/Human_Longevity

2: https://fortune.com/2017/02/21/craig-venter-human-longevity/

Aeroi•9m ago
I raced with him on his boat. During a gybe once, he was swept overboard and the mainsheet wrapped around his torso. He was dragged through the water, but somehow held onto the rail until I was able to pull him back aboard by the loop on his foullies.

He was an interesting guy. He had been a medic during the Vietnam War, and his old boat, Sorcerer II, became a platform for his Global Ocean Sampling Expedition from 2003 to 2010, which discovered millions of new marine microbial genes.

He collected a lot of friends, and definitely a few enemies, and, in his own strange and remarkable way, seemed to have lived a complete human experience here on Earth.

subtextminer•6m ago
You can definitely say that ego was the fountainhead of progress for him!
TuringNYC•6m ago
RIP. I absolutely loved the book A Life Decoded: My Genome: My Life by J. Craig Venter.

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