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Loss of epigenetic information as a cause of mammalian aging

https://www.cell.com/cell/fulltext/S0092-8674(22)01570-7
4•andsoitis•1h ago

How to Test AI Agents When They Never Give the Same Answer Twice

https://adlrocha.substack.com/p/adlrocha-the-eval-problem-how-to
1•adlrocha•6m ago•0 comments

Quickheap: The fastest comparison-based heap?

https://curiouscoding.nl/posts/quickheap/
1•Peter5•7m ago•0 comments

Claude Code and Obsidian – build a second brain <3

https://canatak.substack.com/p/i-dont-need-to-know-everything-i
1•cango35•8m ago•0 comments

What's New in Git 2.54.0?

https://about.gitlab.com/blog/whats-new-in-git-2-54-0/
1•chmaynard•14m ago•0 comments

The Last Principle We Learn to Use

https://gpt.gekko.de/the-last-principle-we-learn-to-use/
1•ekadagami•18m ago•0 comments

Show HN: Enoch – Control Plane for Autonomous AI Research

https://github.com/alias8818/enoch-agentic-research-system
2•aliasocracy•23m ago•0 comments

Grok 'drive an iron nail through the mirror while reciting Psalm 91 backwards'

https://www.theguardian.com/technology/2026/apr/24/musk-grok-x-ai-researchers-delusional-advice-i...
2•iamflimflam1•27m ago•1 comments

Revived Mozilla's BrowserQuest game on popular demand play online for free

https://threej.in/games/browserquest/index.html
1•cryptpal•28m ago•0 comments

Why Did Huawei Build Its Own Programming Language? [video]

https://www.youtube.com/watch?v=ujpl5_TmAaE
2•melchizedek6809•29m ago•0 comments

Why TUIs Are Back

https://wiki.alcidesfonseca.com/blog/why-tuis-are-back/
1•vinhnx•32m ago•0 comments

BTC Pulse – 4-factor composite model · Bitcoin Real-time macro signals

https://btcpulse.vercel.app/
1•tvvocold•33m ago•0 comments

Online Signature Generator

https://www.online-unterschriftgenerator.de/
1•Hamaq•33m ago•0 comments

Who Killed Spirit Airlines?

https://www.thebignewsletter.com/p/who-killed-spirit-airlines
1•chmaynard•34m ago•0 comments

Word Clouds Considered Harmful (2011)

https://jacobharr.is/published/word-clouds
1•Tomte•35m ago•0 comments

Show HN: A modern Git based age-encrypted secrets manager for teams

https://github.com/sayanarijit/cottage
1•sayanarijit•35m ago•0 comments

Local-first Kubernetes UI in a single Go binary

https://github.com/skyhook-io/radar
5•nadaverell•37m ago•2 comments

Executable installer will stop being released with Python 3.16

https://www.python.org/downloads/release/pymanager-261/
2•ankitg12•43m ago•0 comments

Learning Pseudorandom Numbers with Transformers

https://arxiv.org/abs/2510.26792
1•pizza•46m ago•0 comments

Cajal – Local AI that writes peer-reviewed papers with simulated peer review

https://huggingface.co/Agnuxo/CAJAL-4B-P2PCLAW
1•Frank1976•51m ago•0 comments

Quantum computers will break RSA-2048 by February 2032

https://gagliardoni.net/#20260503_rsa_broken_2032
1•tomgag•53m ago•0 comments

Has anyone tried using Hyperframes?

https://github.com/heygen-com/hyperframes
1•nastrofa•53m ago•0 comments

I Don't Vibe Code

https://jacobharr.is/personal/i-dont-vibe-code
1•birdculture•53m ago•0 comments

A Wandering Mind Is an Unhappy One (2010)

https://www.scientificamerican.com/article/a-wandering-mind-is-an-un/
1•the-mitr•57m ago•0 comments

The Human Line Project: Documenting AI Chatbot Harm

https://www.thehumanlineproject.org/
2•thinkingemote•59m ago•0 comments

Show HN: I made a website for couples in a long distance relationship

https://www.couples-questions.com
2•mahfouz22•59m ago•0 comments

AMD Readies Full Open-Source HDMI 2.1 Support for Linux

https://www.techpowerup.com/348723/amd-readies-full-open-source-hdmi-2-1-support-for-linux
3•SockThief•1h ago•0 comments

Context Mode v1.0.0

https://context-mode.mksg.lu/
2•ankitg12•1h ago•1 comments

Musk vs. Altman week 1: Elon Musk says he was duped, warns AI could kill us all

https://www.technologyreview.com/2026/05/01/1136800/musk-v-altman-week-1-musk-says-he-was-duped-w...
2•joozio•1h ago•0 comments

ZenTTY – A terminal that gets out of your way

https://zentty.org/
1•fdb•1h ago•0 comments

Show HN: Julius, a New Lisp Implementation

https://github.com/tgflynn/Julius
2•tgflynn•1h ago•1 comments