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Genetic analysis of circulating metabolic traits in 619,372 individuals

https://www.nature.com/articles/s41586-026-10532-5
2•bookofjoe•45m ago

GLP-1s Linked to Lower Risk of Cancer Spread in Four Tumor Types

https://www.medpagetoday.com/meetingcoverage/asco/121397
1•ascorbic•42s ago•0 comments

A PDF let the internet hear the final words in the cockpit of UPS plane

https://www.cnn.com/2026/05/22/us/plane-crash-audio
1•intrasight•58s ago•0 comments

Dutch FIOD dismantled arm of Stark Industries – bulletproof hoster

https://twitter.com/IntCyberDigest/status/2057847058430656518
1•defly•2m ago•0 comments

Show HN: Lilo – An open source personal AI assistant that lives in Telegram

1•abi•3m ago•0 comments

Fusion energy poised for simpler U.S. review

https://www.axios.com/2026/05/22/fusion-energy-simpler-federal-review
1•Brajeshwar•4m ago•0 comments

The Economic Experiment That Upended Reality

https://www.theatlantic.com/ideas/2026/05/minimum-wage-experiment-worked/687255/
1•JumpCrisscross•4m ago•0 comments

Can SAEs Capture Neural Geometry?

https://www.goodfire.ai/research/can-saes-capture-neural-geometry
1•gmays•5m ago•0 comments

Trump Mobile exposed customers' personal data

https://techcrunch.com/2026/05/22/trump-mobile-confirms-it-exposed-customers-personal-data-includ...
2•rippeltippel•6m ago•0 comments

Starbucks scraps AI inventory tool across North America

https://www.reuters.com/business/starbucks-scraps-ai-inventory-tool-across-north-america-2026-05-21/
1•josephcsible•6m ago•0 comments

DeepSeek makes the V4 Pro price discount permanent

https://api-docs.deepseek.com/quick_start/pricing
4•Tiberium•7m ago•0 comments

Rolling Your Own CIAM-Bad Idea or Horrible Idea? (2024)

https://ciamweekly.substack.com/p/rolling-your-own-ciam-bad-idea-or
1•mooreds•8m ago•0 comments

Ask HN: How would you grow a screen recording app after hitting $3.5K MRR?

1•snazarov92•8m ago•0 comments

Design-Based Vulnerabilities on macOS: Oops, Not a One-Shot Fix

https://imlzq.com/apple/macos/2026/05/15/Design-Based-Vulnerabilities-on-macOS-Oops-Not-a-One-Sho...
1•speckx•9m ago•0 comments

SpaceX Taps Crypto Billionaire to Lead First Crewed Mission to Mars

https://gizmodo.com/spacex-taps-crypto-billionaire-to-lead-first-crewed-mission-to-mars-2000762451
2•bookofjoe•10m ago•0 comments

Leopold Aschenbrenner: Situational Awareness Two Years On

https://philippdubach.com/posts/aschenbrenners-receipts/
1•7777777phil•11m ago•0 comments

Fakellm – a mock OpenAI/Anthropic server for testing

https://github.com/1dg618/fakellm
1•1dag618•12m ago•0 comments

Cannes Film Cost $500k to Make. $400k Was AI Compute Costs

https://www.wsj.com/cio-journal/this-cannes-film-cost-500-000-to-make-400-000-was-ai-compute-cost...
1•JimsonYang•14m ago•0 comments

Ask HN: OpenAI, SpaceX/xAI, Anthropic all to IPO, is this a sign of the peak?

2•virgildotcodes•15m ago•0 comments

Cloudflare Dashboard/API is down

https://www.cloudflarestatus.com/incidents/znll7lfnd35h
3•jnettome•16m ago•0 comments

Where to buy anything AI Powered Search

1•SaadZ777•18m ago•2 comments

Harmonics: Learn about additive synthesis and play with interactive string modes

https://melatonin.dev/additive-synth-comic/what-is-a-harmonic/
2•wlll•20m ago•0 comments

The Minimal Retroreflective Microfacet Model

https://jcgt.org/published/0015/01/04/
1•ibobev•22m ago•0 comments

How to convert between wealth and income tax

https://paulgraham.com/winc.html
30•bifftastic•23m ago•57 comments

Show HN: Pablo – a Chrome extension that copies UI from any website

https://www.usepablo.dev/
2•rayansaleh•24m ago•0 comments

Brethof-mind – local long-term memory for Claude Code (SurrealDB, no API)

https://github.com/BrethofAI/brethof-mind
3•brethofai•24m ago•0 comments

Self-Hosting a Forgejo Runner for Codeberg Actions

https://hmmr.online/posts/codeberg-forgejo-runner/
2•ZanderHammer•24m ago•0 comments

I have no mouth, and I must scream [pdf]

https://galacticjourney.org/stories/I_Have_No_Mouth_and_I_Must_Scream_-_Harlan_Ellison.pdf
3•ig1201•24m ago•0 comments

You Are Optimizing for the Wrong Metric

https://lucaspauker.com/articles/optimizing-for-the-wrong-metric/
3•lucaspauker•24m ago•0 comments

I use Obsidian and Hermes: Actual use cases and setup

https://metedata.substack.com/p/013-my-hermes-and-obsidian-set-up
5•young_mete•25m ago•0 comments

Luddite Lab

https://labor.dair-institute.org/about
3•monkaiju•25m ago•0 comments