These drugs seem to change something fundamental that reduces problematic behavior.
[1] https://www.youtube.com/watch?v=SSEjPuR11_k
[2] Diekhof EK, Nerenberg L, Falkai P, Dechent P, Baudewig J, Gruber O. Impulsive personality and the ability to resist immediate reward: an fMRI study examining interindividual differences in the neural mechanisms underlying self-control. Hum Brain Mapp. 2012 Dec;33(12):2768-84. doi: https://doi.org/10.1002/hbm.21398 Epub 2011 Sep 21. PMID: 21938756; PMCID: PMC6870517.
I wonder if you can do a simple experiment between glp and non glp users where you try and measure various biological response to giving someone say $20?
Going further I wonder if it affects other responses like pain response. How long might you keep your hand on a plate warming up? I seem to remember that sort of experimental setup in my undergrad days of signing up for every psychology department experiment under the sun for beer money.
In other words there's a concern of creating metaphorical "zombies" who lack a "force of will"
I'm fairly sure that part of the reason they reduce neuroinflammation is because of pulmonary GLP-1 mechanisms. (Lung and brain are quite intimately connected, as is inflammation to the other two. As well as the gut. And… metabolism.)
Neuroinflammation is very behavior-modifying.
(Neuroinflammation kind of makes sense as an untamperable side-channel of information for neuronal processes – out of band; Protective. Can't think yourself to death.)
There's tons of papers to read. You wouldn't believe how much accurate and correct and actionable and predictive scientific information exists that nobody reads.
Read primary sources. Anyone can read. Don't let anyone tell you that you can't read. Least of all yourself.
Bender•1h ago
grayhatter•1h ago
toomuchtodo•55m ago
The aggregate potential benefit is so high and the risk and cost reasonably low. Certainly, no one should ever be forced to take it, or be experimented on without their explicit, informed consent (and "experimented on" in this context is "taking the GLP-1 already and we're just tracking the outcomes at scale").
asdff•54m ago
devmor•42m ago
asdff•38m ago
WarmWash•31m ago
Bender•31m ago
If I were a prison guard or warden I would be happy to encourage prisoners to use any compound that may improve their impulse control which is likely one of the root causes of their incarceration in the first place.
evanjrowley•1h ago