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ECAA-workflow: deterministic workflow compiler for FAIR bioinformatics

https://github.com/SuLab/ECAA-workflow
4•ahueb•1h ago

Comments

ahueb•1h ago
Agentic LLM assistants are powerful for bioinformatics and computational biology workflows but stochasticity, auditability, and sharability are large weak points for existing systems.

I have been developing ECAA-workflow to close those gaps by using LLM chat intake to drive a deterministic Rust workflow compiler which translates a user request into a task centric directed acyclic graph representing the workflow.

An execution harness runs plain Claude Code CLI in reproducible containers on the backend. All workflow packages are tracked with git for versioning and include RO-Crate registries for FAIR data sharing.

Packages are deterministically reproducible and re-executable without the need for an LLM agent as all environments and scripts are saved within the package.

The system allows branching so a user can rerun any task node with different methods or parameters based on results. Full provenance of all user and agent decisions are logged for comprehensive auditability.

Can you build a recognizable World Map in under 500 bytes?

https://www.experimentlog.com/blog/building-a-world-map-with-only-500-bytes
1•iweczek•45s ago•1 comments

"That's a interesting starting point. Who is made out of meat?"

https://thelonggoodbye.net/p/thats-a-really-interesting-starting
1•adamfletcher•51s ago•0 comments

How to figure out what you want

https://hils.substack.com/p/how-to-figure-out-what-you-want
1•jger15•1m ago•0 comments

Show HN: Reminal – A zero-config SSH alternative (no open ports, no keys)

https://github.com/harshalgajjar/reminal
1•harshalgajjar•1m ago•0 comments

Freedom Isn't Free (2018)

https://logicmag.io/failure/freedom-isnt-free/
1•robtherobber•2m ago•0 comments

The GNU Emacs Architecture: Unlocking the Core [pdf]

https://www.diva-portal.org/smash/get/diva2:2052282/FULLTEXT01.pdf
1•cenazoic•2m ago•1 comments

Ethical NBA Championships, Ranked

https://pudding.cool/2026/06/ethical-champions/
1•surprisetalk•4m ago•0 comments

Trust Is Not Governance

https://www.blackhc.net/essays/trust_is_not_governance/
1•blackhc•4m ago•0 comments

Applying Artificial Intelligence to Trading (2021)

https://www.hudsonrivertrading.com/hrtbeat/ai-trading/
1•eustoria•5m ago•0 comments

The Goldilocks customizable select height

https://jakearchibald.com/2026/goldilocks-select-height/
1•eustoria•5m ago•0 comments

Cloudflare Attribution Business Insights

https://blog.cloudflare.com/attribution-business-insights/
1•sourcecodeplz•6m ago•0 comments

The test suite was the incident

https://christophermeiklejohn.com/ai/zabriskie/agents/reliability/testing/2026/06/10/the-test-sui...
1•azhenley•6m ago•0 comments

Canada to compete in the 2027 Eurovision Song Contest

https://www.politico.eu/article/canada-joins-eurovision-song-contest/
1•JumpCrisscross•6m ago•0 comments

Show HN: GovAuctions.app now in US,UK,CA,AU with deal scores and bid estimates

https://govauctions.app
1•player_piano•7m ago•0 comments

Employers who laid off workers citing AI are starting to regret it

https://www.cnbc.com/2026/07/01/employers-who-laid-off-workers-for-ai-are-reversing-their-decisio...
2•rustoo•7m ago•1 comments

Show HN: Clockjumper – An Intervibed Project

https://clockjumper.com/
1•HaphazardGuess•8m ago•0 comments

Aurum Foundation Says It's an AI Infrastructure Provider. It's a Ponzi Scheme

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1•bmcdresson•8m ago•0 comments

Context window exhaustion is a practitioner problem, not just a system problem

https://truenorthagentic.com
1•MathewCrawford•8m ago•0 comments

Recursive AI Research Skill for Claude Code / OpenClaw / Codex

https://github.com/Toadoum/ai-research-skill
2•Toadoum•8m ago•0 comments

Loqa: Free Discord Alternative

https://loqa.chat/
1•MrBuddyCasino•10m ago•0 comments

Marine expedition uncovers 31 new species in two weeks

https://www.theguardian.com/environment/2026/jun/26/marine-expedition-uncovers-31-new-species-two...
1•gmays•10m ago•0 comments

I Built a Watchman for My Servers

https://akashrajpurohit.com/blog/i-built-a-watchman-for-my-servers/
2•ghostfoxgod•10m ago•0 comments

How to (Not) Spend $10k/Wk on Coding Agents

https://allenpike.com/2026/how-to-not-spend-10k-on-coding-agents/
2•dennispi•11m ago•0 comments

The Complete Guide to Caveman

https://aifordevelopers.substack.com/p/the-complete-guide-to-caveman
3•hamidreza23•12m ago•0 comments

Three HPC Gurus Ask: Do We Still Need GPUs?

https://www.nextplatform.com/compute/2026/06/30/three-hpc-gurus-ask-do-we-still-need-gpus/5264552
2•rbanffy•12m ago•0 comments

The Fonts of the U.S. Federal Courts

https://daringfireball.net/2026/05/the_fonts_of_the_us_federal_courts
2•JumpCrisscross•14m ago•0 comments

Show HN: Thumbprint – A network fingerprint observatory

https://thumbprint.me/
1•elpy1•17m ago•0 comments

Linux Foundation: Akrites – Patch the Commons, Together

https://akrites.org/
2•throwoutway•17m ago•0 comments

Fenris Creations (FKA CCP Games) Opens Carbon Engine to the World

https://fenris.com/news/2026/fenris-creations-opens-carbon-engine-to-the-world
1•lentil_soup•18m ago•0 comments

Amazon blames piracy apps with malware for killing new Fire Stick sideloading

https://arstechnica.com/gadgets/2026/06/exec-blames-malware-threat-for-amazon-blocking-sideloadin...
1•Brajeshwar•19m ago•0 comments