frontpage.
newsnewestaskshowjobs

Open Source @Github

fp.

Open in hackernews

Cannabis Users Face Substantially Higher Risk of Heart Attack

https://www.acc.org/about-acc/press-releases/2025/03/17/15/35/cannabis-users-face-substantially-higher-risk
26•RickJWagner•1h ago

Comments

RickJWagner•1h ago
It’s starting to look like THC ( found in gummies, too ) causes vascular problems.
PaulHoule•41m ago
Before we got Ozempic there was great hope for

https://en.wikipedia.org/wiki/Rimonabant

which blocks the receptor that THC binds to and led to weight loss and further improvements of the “metabolic syndrome” beyond weight loss alone. Unfortunately it caused major depression in some people including suicide.

So looking at it that way it would be no surprise that cannabis causes weight gain and metabolic syndrome and in fact my experience is that if I am using cannabis I get a few kg. I think that is the THC and on top of that if you are smoking you are inhaling small particles that turn your blood into sludge (e.g. your blood is a “complex fluid” with cells in it that can be damaged) and doing damage to your lungs and capillaries and promoting inflammation and all that.

ChrisMarshallNY•18m ago
You get the munchies

https://www.youtube.com/watch?v=yN1AQDxwrSg

embedding-shape•16m ago
> researchers were unable to account for several potential confounding factors including the duration and amount of cannabis use or the use of tobacco or other drugs.

Personally I'd wager a bet it's the tobacco and/or smoking that is the harmful part, but it kind of dumbfounds me they failed to account for "details" like "duration and amount of cannabis use", that feels like a very vital thing to control for. Nothing is good for you in too great amounts, even water, so not taking that into account seems to not really give reliable and trustworthy results.

yieldcrv•14m ago
I’m annoyed by the bifurcated regulatory regime

Substances approved by the FDA are done based on specific treatments, with multiple trials and approval per use case

Substances declared scheduled are illegal by the substance itself, instead of per use case

paradoxically because there is no FDA approved use case and almost no way to get one

meaning that places in the US that diverge in legality and are ignored by the federal government have done so without any clinical trial, which would be some level of peer reviewed objective information by use case instead of the whole substance

we can’t even get a simple list of side effects, or a disclaimer about what kind of users shouldn’t use it

only anecdotes

that annoys me and it’s not just about weed

gchamonlive•11m ago
Would be nice to know how much of a role a sedentary lifestyle plays in it or if it puts everyone at risk regardless of other habits. Maybe this just means you need to do cardio several times a week to keep using THC.

The Lion, The Witch, and the audacity of recruiters

https://hauleth.dev/post/the-lion-the-witch-and-the-aduacity-of-recruiter/
1•birdculture•2m ago•0 comments

Matrix Multiplication on Blackwell

https://www.modular.com/blog/matrix-multiplication-on-nvidias-blackwell-part-1-introduction
1•skidrow•5m ago•0 comments

Saving tokens and "Let me try something else" infinite loop in Coding Agents

https://cimons.com/article/saving-tokens-let-me-try-something-else-infinite-loop-in-coding-agents
1•etcimon•5m ago•1 comments

Toward Better Hip Kernel Generation for AMD GPUs

https://scalingintelligence.stanford.edu/blogs/hipkernels/
1•skidrow•5m ago•0 comments

FlashAttention-4: Algorithm and Kernel Pipelining Co-Design

https://research.colfax-intl.com/flashattention-4-algorithm-and-kernel-pipelining-co-design-for-a...
1•skidrow•6m ago•0 comments

Notes on Amazon vs. Perplexity

https://educatedguesswork.org/posts/notes-amazon-perplexity/
1•gmays•7m ago•0 comments

Why Your Brain Will Always Defend Complexity

https://savvynormie.com/why-your-brain-will-always-defend-complexity/
1•ExMachina73•10m ago•0 comments

TabFont – guitar tabs rendered as you type

https://philatype.com/tabfont/
1•ChrisArchitect•10m ago•0 comments

Scheme Is a Hoot

https://gracefulliberty.com/notes/scheme-is-a-hoot/
1•signa11•12m ago•0 comments

Anatomy of Prompt Injection

https://medium.com/@kirill89/anatomy-of-prompt-injection-d97ddaea9089
1•k1r111•12m ago•0 comments

Show HN: Neil the Seal Game

https://neiltheseal.app/
2•dalemhurley•13m ago•0 comments

Tell HN: FileVault does not protect Wi-Fi passwords on macOS 26

1•turbidimeter•13m ago•0 comments

Show HN: CAVS – Open-source content-addressable updates for game assets

https://github.com/orelvis15/cavs-oss
1•orelvis15•14m ago•0 comments

Show HN: Essential Media Player – A web-based (PWA) local media player

https://essentialmediaplayer.com/
1•ZuLuuuuuu•15m ago•0 comments

Researchers Create Self-Replicating Seedbox in Quest for Decentralized Democracy

https://torrentfreak.com/researchers-create-self-replicating-seedbox-in-quest-for-decentralized-d...
1•synctext•15m ago•0 comments

Help Us Save MeshCore

https://blog.meshcore.io/2026/07/04/help-us-save-meshcore
1•geerlingguy•20m ago•0 comments

No-AI Label

https://en.wikipedia.org/wiki/No-AI_label
3•amelius•27m ago•0 comments

Social Geo App on AT Proto

https://pinnd.place/login
1•colomolo•28m ago•1 comments

JadePuffer ransomware used AI agent to automate entire attack

https://www.bleepingcomputer.com/news/security/jadepuffer-ransomware-used-ai-agent-to-automate-en...
2•Brajeshwar•29m ago•0 comments

Intelligent-Data /S

https://github.com/nicholascordova01/INTELLIGENT-DATA
1•alex_hirner•31m ago•0 comments

BSDun – Linux kernel module to load FreeBSD ELF binaries

https://gitlab.com/megastallman/bsdun
3•Tiberium•31m ago•0 comments

Beyond Horizon Analysis: Axiom Space – The First Orbital Real Estate Platform

https://beyondhorizonforesight.substack.com/p/beyond-horizon-analysis-axiom-space
1•beyondhorizonfs•31m ago•0 comments

Show HN: Daily Refreshed drop-in replacement for LiteLLM's model price map

https://cloudprice.net/models/api
2•gaploid•34m ago•0 comments

Show HN: Build offline-first web apps in pure Go and HTML

https://swag.mills.io
1•prologic•36m ago•0 comments

VapourDeck

https://spritesmods.com/?art=vapourdeck&f=rss
1•rcarmo•36m ago•0 comments

But what is quantum computing? (3blue1brown 2025)

https://www.youtube.com/watch?v=RQWpF2Gb-gU
4•andromaton•36m ago•1 comments

Generative AI like Midjourney creates images full of stereotypes

https://restofworld.org/2023/ai-image-stereotypes/
2•vinnyglennon•39m ago•1 comments

Show HN: Minicraft - Running Minecraft Classic from a Single Twitter Post

https://github.com/Kuberwastaken/minicraft
2•kuberwastaken•39m ago•0 comments

No Amazon? No problem:remote island built its own online shopping service

https://restofworld.org/2022/online-shopping-in-the-middle-of-the-ocean/
1•vinnyglennon•41m ago•0 comments

Running the '80s DECUS Star Trek game on my new MUMPS 76 interpreter

https://github.com/rochus-keller/MUMPS/blob/main/Readme.md
2•Rochus•43m ago•1 comments