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Drug Discovery Has No Magic Wands by Daphne Koller

https://www.a16z.news/p/drug-discovery-has-no-magic-wands
1•eamag•52m ago

Natura Non Facit Saltus

https://en.wikipedia.org/wiki/Natura_non_facit_saltus
1•nill0•1m ago•0 comments

MDHero: A Markdown viewer and editor Windows was missing

https://mdhero.app/windows/
1•thunderbong•2m ago•0 comments

Blitz Agent Your specialized agent -> https://blitzagent.studio

1•rvey•2m ago•0 comments

Show HN: Six years of running a period tracker app with no subscription, no ads

https://simpluna.app/en
1•gaishimo•7m ago•0 comments

Show HN: Feedback widget with screenshots, annotations, and AI triage

https://github.com/makethisbetter/makethisbetter-js
3•ken2049•8m ago•0 comments

1. Show HN: Paste a job listing, see if it's still live on employer's own site

https://rolesweep.com/is-it-live
1•chetanba•8m ago•0 comments

Three Six Mafia – Data about "6/6/6 dating" (2024)

https://divingintheshallowend.com/three-six-mafia/
9•embedding-shape•10m ago•0 comments

Spec-Driven Development: The New Waterfall

https://medium.com/@ramtop/spec-driven-development-the-new-waterfall-8426a908d4da
2•tarkaTheRotter•10m ago•0 comments

Why is Anthropic destroying books?

https://www.theguardian.com/commentisfree/2026/aug/05/anthropic-ai-destroying-books
4•robaato•10m ago•0 comments

27B model running sub 7W

https://www.youtube.com/watch?v=fyL96mW3SaU
2•thomaslanning•12m ago•1 comments

The Fish Who Could Not Imagine Air

https://www.novaspivack.com/essays/the-fish-who-could-not-imagine-air
2•surprisetalk•15m ago•0 comments

An Invasive Mosquito Spreading with Alarming Speed, Threatening Africa's Cities

https://www.nytimes.com/2026/08/04/us/politics/mosquito-africa-anopheles-stephensi.html
2•thelastgallon•16m ago•0 comments

Show HN: Pistachio – Declarative schema management for PostgreSQL

https://github.com/winebarrel/pistachio
1•winebarrel•16m ago•0 comments

Identity and Substitutivity(1971) [pdf]

https://ncatlab.org/nlab/files/Cartwright-IdentityAndSubstitutivity.pdf
1•nill0•16m ago•0 comments

Data-centre reality check could slam brakes on AI earnings boom

https://www.reuters.com/commentary/reuters-open-interest/data-centre-reality-check-could-slam-bra...
1•mapping365•17m ago•0 comments

Show HN: Ssplax – model and solve constrained operational decisions

https://ssplax.com/app/
1•abanoubey•17m ago•0 comments

Social Darwinists to tech bros: tracing the long fight against equality in US

https://www.theguardian.com/books/2026/jul/21/kim-phillips-fein-country-of-lords
2•robtherobber•17m ago•0 comments

Quiddity and Haecceity

https://www.openhorizons.org/quiddity-and-8203haecceity-whatness-and-thisness-in-a-world-of-becom...
1•Bluestein•19m ago•0 comments

Show HN: Create tweet-style and text-first social posts

https://www.postsfromtemplates.com/
1•StanleySathler•20m ago•0 comments

Findphone: Locate a nearby Bluetooth device by signal strength

https://github.com/ben-z/findphone
1•helsinkiandrew•21m ago•0 comments

1899 Missed the Roomba

https://heyjonny.dev/posts/1899-missed-the-roomba/
1•heyjonny•22m ago•0 comments

Every Noise at Once

https://everynoise.com/
1•0x4e•22m ago•1 comments

Ask HN: How do you correct spatial reasoning of LLMs?

2•mstaoru•22m ago•2 comments

Objects That Explain America

https://www.nytimes.com/interactive/2026/08/04/opinion/museum-of-america.html
1•reaperducer•24m ago•0 comments

eBay's 1995 Debut

https://dfarq.homeip.net/ebays-1995-debut/
1•jnord•24m ago•0 comments

Show HN: Ambient Capture Engine

https://github.com/Rafaelpta/litepipe
1•rafaepta•26m ago•0 comments

Why the Legendary Erdős Problems Are Falling to AI

https://www.quantamagazine.org/why-the-legendary-erdos-problems-are-falling-to-ai-20260803/
2•pseudolus•26m ago•0 comments

Show HN: Claude-account now works on macOS too

https://github.com/hamzarehmandeveloper/claude-account/releases/tag/v0.2.0
1•hamza_rehman•29m ago•0 comments

Show HN: OdeCare – radar-based monitoring for aging parents, no wearables

https://odecare.com/
1•decaster3•31m ago•0 comments

How Internet Fighting Works

https://www.smbc-comics.com/comic/2013-04-07
2•fanf2•34m ago•0 comments