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Midlife Vascular Risk Burden and Dementia-Free Survival Years

https://www.neurology.org/doi/10.1212/WN9.0000000000000152
14•bookofjoe•1h ago

Comments

brandonb•20m ago
Previous studies have shown that heart health at 50 predicts brain health at 75.

This study is interesting in that it quantifies the benefit as 12.5 extra dementia-free years. People with 0 risk factors had 30 years of dementia-free survival, vs 17.5 years for people with all 3 risk factors measured.

The risk factors in this specific study are blood pressure, diabetes (HbA1c), and smoking. You could reasonably also include cholesterol/ApoB, inflammation (hs-CRP), and perhaps Lp(a) as potential risk factors.

asdfman123•10m ago
Yes. The time to fix your health is now. Any unhealthy habits put time on the biological clock, and they'll just get harder to undo later. This is true if you're 20, 40, or 60. Plaque literally starts building up on your arteries even if you're a healthy teenager. It all adds up.

But don't read this and panic or beat yourself up, that's a waste of energy. That's choosing the punishment instead of the fix.

Instead, quietly start doing one small healthy habit. If you stop, don't beat yourself up, just quietly start doing it again. Stubbornly persist until you've won.

The Download: AI agents for science, and the "censorship-industrial complex"

https://www.technologyreview.com/2026/08/10/1141526/the-download-ai-agents-science-censorship-ind...
1•joozio•3m ago•0 comments

What Does the Humbling of Leopold Aschenbrenner Mean for the A.I. Bubble?

https://www.newyorker.com/news/the-financial-page/what-does-the-humbling-of-leopold-aschenbrenner...
2•mitchbob•7m ago•1 comments

Open4D, a community-driven open-source ecosystem for 4D spatial data

https://github.com/open4dfoundation/Open4D
1•open4d•8m ago•1 comments

OpenBao Features – Recursive Lists (Scan) & Filtering

https://openbao.org/blog/features-recursive-list/
1•cipherboy•9m ago•0 comments

Waymo Is Growing Faster Than Ever. So Are Its Glitches

https://www.nytimes.com/2026/08/10/technology/waymo-expansion-edge-cases.html
2•harmmonica•9m ago•0 comments

LLM Performance and Following Requirements

https://492ab3fb.danpalmer-me.pages.dev/2026-08-09-llms-and-requirements/
2•speckx•10m ago•0 comments

Show HN: Draw any shape and hear what it sounds like as a drum

https://baselashraf81.github.io/eigendrum/
1•BaselAshraf81•10m ago•0 comments

Centaur 2.0

https://twitter.com/gakonst/status/2086846192701640817
2•anr0•11m ago•1 comments

I built a free web coding curriculum for beginners and teachers

https://aicodingeducator.com/
3•Julesman•14m ago•1 comments

Claude Code self-improved through conversation, not the memories it saved

https://shojin.dev/blog/claude-code-improved-through-conversation-not-memories/
2•anndvision•14m ago•1 comments

With Flying Pen, When Mortals Sleep

https://brianschrader.com/archive/with-flying-pen-when-mortals-sleep/
1•sonicrocketman•14m ago•1 comments

LexisNexis pulls three services offline after suspicious server activity

https://www.theregister.com/off-prem/2026/08/10/lexisnexis-blames-outage-on-unusual-server-activi...
3•joebuckwilliams•14m ago•0 comments

I reverse engineered Meta's Muse Code binary and found hidden agent workflows

https://runtimewire.com/article/exclusive-meta-s-muse-code-binary-reveals-hidden-agent-workflows-...
2•ryanmerket•16m ago•0 comments

Agentic coding needs human sign-off tied to physical reality

https://patrickaudley.com/posts/human-signoff-for-agentic-code.html
1•antoineMoPa•17m ago•0 comments

Show HN: Run outbound and lead gen from Claude Cowork, no sales tools

https://github.com/skyzer/skills
1•skyzer•20m ago•0 comments

Falsehoods programmers believe about addresses (2013)

https://www.mjt.me.uk/posts/falsehoods-programmers-believe-about-addresses/
1•throw0101a•22m ago•0 comments

ChainDrop supply chain compromise: Anatomy of a self-propagating worm

https://www.microsoft.com/en-us/security/blog/2026/08/04/chaindrop-supply-chain-compromise-anatom...
2•mooreds•22m ago•0 comments

John Crowley Has Died

https://www.programmablemutter.com/p/john-crowley-has-died
3•paulpauper•24m ago•1 comments

Poll shows support for proportional representation in the US

https://www.npr.org/2026/08/10/nx-s1-5920312/proportional-representation-poll
1•marojejian•24m ago•1 comments

Just how big is the hidden leverage of AI hyperscalers?

https://www.ft.com/content/a0a07cce-6d19-4b1e-a73b-9855a06ba7b3
4•petethomas•24m ago•0 comments

Stop Fleeing the Base: Security Needs to Learn to Code

https://oreillyradar.substack.com/p/the-base-is-under-attack
1•tmo9d•25m ago•0 comments

Show HN: Jsonseek – Token-efficient JSON/JSONL navigation for LLM agents

https://github.com/lo2589/JSONSEEK
1•yoliliya•25m ago•0 comments

Bill Goichberg, Who Reshaped Competitive Chess in the U.S., Dies at 83

https://www.nytimes.com/2026/08/08/us/bill-goichberg-dead.html
2•paulpauper•26m ago•1 comments

The Resident Project

https://snowballons.com/writing/the-resident-project/
1•jonniebullie•27m ago•0 comments

Kyutai MuScriptor: Automatic Multi-Instrument Transcription

https://kyutai.org/blog/2026-07-10-muscriptor/
1•Sebastian_09•27m ago•0 comments

Show HN: Is your AI hallucinating? The big labs won't tell you but we will

https://www.telluvian.ai/blog/is-your-ai-hallucinating
3•galois123•27m ago•1 comments

Neo

https://hughhowey.com/introducing-neo/
3•hentrep•27m ago•0 comments

Mcmaster.ai

https://www.mcmaster.com/
3•gregsadetsky•28m ago•1 comments

Launch HN: Stoa Markets (YC S26) – A Marketplace for GPUs and AI Servers

https://www.stoaexchange.com
6•erenberke•28m ago•0 comments

The Day the AI Act Grew Teeth: GPAI Enforcement Goes Live

https://simonroses.com/2026/08/the-day-the-ai-act-grew-teeth-gpai-enforcement-goes-live/
2•speckx•29m ago•0 comments