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70% of new drugs approved by FDA in 2024 were based on a single study

https://www.cidrap.umn.edu/public-health/more-two-thirds-new-drugs-approved-fda-2024-were-based-single-study
1•giuliomagnifico•56m ago

Show HN: Nuzzle – adorable live wallpapers of your pets

https://usenuzzle.com
1•13001r•10s ago•0 comments

Against Dumb Vibe Coding, Not Vibe Coding

https://funnygeek.com/essays/vibe-coding-speech/
1•ifoo•1m ago•1 comments

Show HN: Drop a SQL schema, get an interactive ER diagram

https://mcdview.dev/
1•PatuDev•1m ago•0 comments

Mitchell Hashimoto: Basic Superlogical Demo

https://twitter.com/mitchellh/status/2093451043661316217
1•mdrachuk•4m ago•0 comments

The U.S. Munitions Crisis

https://www.cfr.org/articles/the-u-s-munitions-crisis
1•Betelbuddy•4m ago•0 comments

Show HN: Time tracking for solo consultants that ends in a PDF invoice

https://hourtobill.com/demo
1•Stackedboost•5m ago•0 comments

Tja – TUI for learning German verbs in your terminal, one-armed-bandit style

https://github.com/progapandist/tja
1•progapandist•6m ago•1 comments

US Threatens Britain over Falklands

https://www.telegraph.co.uk/world-news/2026/08/28/us-uk-boost-defence-spending-lose-falklands-sup...
1•Betelbuddy•8m ago•0 comments

Iceland votes against restarting talks on joining EU

https://www.bbc.com/news/articles/c70le8ed1plo
2•vinni2•8m ago•0 comments

Show HN: Train 300M/32-Layer Model in 1.5GB RAM on Base M1 Mac

1•vlad_kalinkin•9m ago•0 comments

Only believe what you can validate: a verification framework for agentic AI

https://devblogs.microsoft.com/all-things-azure/only-believe-what-you-can-validate/
1•yani__•10m ago•0 comments

Delhi Metro Jazz

https://www.delhimetrojazz.com/
1•mscholz•12m ago•0 comments

Veldo: Stop paying for App Store keywords that never pay back

https://veldo.app/
1•welsenesbros•14m ago•0 comments

Show HN: Rose – reusable foundation embeddings for industrial 1H NMR

https://github.com/romboai/rose-1h-nmr
1•zaza3311•15m ago•0 comments

The Complex Tech Behind Growing Diamonds in Minutes [video]

https://www.youtube.com/watch?v=SPAMTs6Ug20
1•binyu•16m ago•0 comments

Berlin is being blackmailed by hackers

https://www.bbc.com/news/articles/cm2q7gv3l5qo
2•dudefeliciano•18m ago•0 comments

VibeGuard – security linter for AI-generated code

https://github.com/zeroFhacker/vibeguard
1•obadafid•20m ago•0 comments

Lamb Grazing in Solar Farms

https://spacedaily.com/b-lambs-grazing-under-an-oregon-solar-farm-had-38-percent-less-grass-in-fr...
2•anu7df•24m ago•0 comments

My fat loss experiments with ChatGPT and water fasting

https://community.webminal.org/t/my-fat-loss-experiments-with-chatgpt-and-water-fasting/8846
4•giis•25m ago•0 comments

Observations Around Prominent Programmer Sentiment and AI

https://blog.g9n.com/observations-around-prominent-programmer-sentiment-and-ai
1•gb2d_hn•26m ago•0 comments

Fair Work Commission condemns 'plain wrong' AI legal advice

https://www.abc.net.au/news/2026-08-29/fair-work-commission-condemns-ai-legal-advice/107089766
4•martyvis•26m ago•0 comments

What We Tell AI

https://www.whatwetellai.com/
3•thm•30m ago•0 comments

Structure is cheaper than intelligence

https://jeroensangers.com/2026/08/30/structure-is-cheaper-than-intelligence.html
3•meetpateltech•36m ago•0 comments

A pure Rust Layer-1 with 2,048 concurrency lanes and static scheduling

https://synapticchain.xyz
2•abdulshabazz•37m ago•0 comments

Ask HN: Which repos have merged PRs worth reading?

1•justabuilder•41m ago•0 comments

RoyalSonic – Affordable business email and groupware suite

https://www.royalsonic.com/shop-2/
1•dhamanij•43m ago•0 comments

Which repos have merged PRs worth reading?

1•justabuilder•43m ago•0 comments

Does Computer Science Need Computers?

https://www.quantamagazine.org/does-computer-science-need-computers-20260828/
2•Michelangelo11•44m ago•2 comments

Spark: Sparklines in your shell

https://git.zx2c4.com/spark/about/
10•hskimse•44m ago•0 comments

Java at 30 Essay [pdf]

https://bracha.org/java_at_30_essay.pdf
2•__patchbit__•49m ago•0 comments