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Show HN: Checkout this open-source, local-first bioinformatics/AI desktop app

https://github.com/Liatir/liatir-app
1•Suffro•48m ago
So the basic idea behind Liatir is to have a desktop environment that works like a virtual lab for bioinformatics to do your work locally, without having to send data to a cloud service or glue together a bunch of separate tools and interfaces.

You shouldn’t need to write a single line of code to use it, but if you do know how to code, it's as extensible as you want it to be with the plugin system supporting Node, Python and Rust.

It provides regular bioinformatics tools, local scientific AI models, integrations with workflow systems such as Nextflow, API calls when you need to connect to external data or environments, scientific viewers, and visual pipelines that tie all of those pieces together.

Oh and the AI models are self-contained boxes so you do not need to set up anything and just run them.

Hope you'll find this interesting.

Ultra Low Latency Solution with U4 enables high-velocity trading

https://cloud.google.com/blog/topics/financial-services/ultra-low-latency-solution-with-u4-enable...
1•ilreb•35s ago•0 comments

A sense of control over workplace technology linked to wellbeing, productivity

https://workplaceinsight.net/a-sense-of-control-over-workplace-technology-may-be-linked-to-wellbe...
1•mikelgan•1m ago•0 comments

Show HN: CrowDB – an iceberg table storage single Docker container

https://buzzcrow.github.io/blog/run-iceberg-in-one-container/
1•crowdb•2m ago•0 comments

A Cop's Case for Flock

https://worksinprogress.co/issue/a-cops-case-for-flock/
1•skadamat•3m ago•0 comments

The Dawn of the Age of the Exoskeleton

https://theconversation.com/the-dawn-of-the-age-of-the-exoskeleton-281804
1•speckx•4m ago•0 comments

Christa Pike's lawyers hold press conference after she regains consciousness

https://www.theguardian.com/us-news/live/2026/oct/07/christa-pike-lawyers-live-updates-tennessee-...
1•MaysonL•4m ago•0 comments

FortiBleed still a bleeding nuisance as FBI confirms ongoing attacks

https://www.theregister.com/security/2026/10/07/fortibleed-still-a-bleeding-nuisance-as-fbi-confi...
2•Bender•6m ago•0 comments

Trump Mobile customers' data dumped – and some never even received their device

https://www.theregister.com/security/2026/10/06/trump-mobile-customers-data-dumped-and-some-never...
3•Bender•8m ago•0 comments

Trade group crunches numbers on Trump's impossible push for 100% US-made tech

https://arstechnica.com/tech-policy/2026/10/trade-group-crunches-numbers-on-trumps-impossible-pus...
2•Bender•9m ago•0 comments

Biohub leads $1.8B initiative to build AI-ready biological datasets

https://biohub.org/news/virtual-biology-initiative-expansion/
1•maksimilian•9m ago•0 comments

Tecotype: macOS mail app for professionals who live in their mailbox

https://tecotype.com/threads
1•sea-gold•9m ago•0 comments

Show HN: Configstream – Live config for Spring Boot via MongoDB change streams

https://github.com/configstream/configstream
1•reachkhajam•10m ago•0 comments

An OpenAI Insider Explains Why He Quit [video]

https://www.youtube.com/watch?v=JIMXEuT_ZAU
1•ptrhvns•14m ago•0 comments

IBM's Selective Sequence Electronic Calculator (2003)

https://www.columbia.edu/cu/computinghistory/ssec.html
1•goshtasb•14m ago•0 comments

Ukrainian drones swarmed Moscow last night

https://twitter.com/actfast/status/2107691638151950741
3•znnajdla•14m ago•0 comments

DatCal

https://play.google.com/store/apps/details?id=datyaltech.android.familycal&hl=en
1•makdatyal•15m ago•0 comments

LC-3 Assembly Tutor-AI tutor that explains what the machine is doing

https://ai-assembly-tutor-v2-9a6d593b-1.telnyxcompute.com/
1•harpreetseehra•16m ago•0 comments

Open source 160 sound visualization experiments

https://www.kagan.in/iwrzwr/visual-archive/
3•kaganin•17m ago•0 comments

My static site was serving my internal docs

https://tminuslabs.space/serving-secrets
1•tminuslabs•19m ago•0 comments

Show HN: Trigora – durable execution without history replay

https://github.com/trigora-dev/trigora
1•hypervs•19m ago•0 comments

Show HN: Bigwords.page – Turn any screen into a sign. The URL is the app

https://bigwords.page/
2•SpeakingOfBrad•19m ago•1 comments

Show HN: Luke – Voice planning for coding agents

https://tryluke.dev/
2•cpan22•19m ago•0 comments

AsyncAPI Initiative

https://www.asyncapi.com/en
1•saikatsg•20m ago•0 comments

Nokia-style Android launcher – Simple Dumbphone

https://nokiaretrophone.mr-ahhk1412.chatgpt.site/
1•ahhk•20m ago•0 comments

Show HN: Srl – Angular-style web components with no build step

https://github.com/BernardoGiordano/srl
1•berngiordano•21m ago•0 comments

Redundancy Is the Engine of Progress

https://world.hey.com/dhh/redundancy-is-the-engine-of-progress-76499402
2•gpi•21m ago•0 comments

Boredpolymath/Truth-Beacon

https://github.com/boredpolymath/truth-beacon
1•boredpolymath•21m ago•0 comments

Morning Coffee Simulator

https://coffee.9000ish.uk/
2•gregsadetsky•23m ago•0 comments

Thank You Indonesia for the Clean Air

https://thankyouindoforthecleanair.web.app/
2•water-drummer•24m ago•0 comments

Show HN: The Last SaaS – An open source headless SaaS for agents and assistants

https://thelastsaas.com/
2•mkly•24m ago•0 comments