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Counterintuitive facts about U.S. healthcare

https://halletecco.substack.com/p/10-facts-about-us-healthcare-that
1•brandonb•27s ago•0 comments

Inbox Zero for Privacy, Not Productivity

https://xn--gckvb8fzb.com/inbox-zero-for-privacy-not-productivity
1•surprisetalk•1m ago•0 comments

Show HN: Documenting the file formats and engine of Elder Scrolls: Redguard 1998

https://michidk.github.io/redguard-preservation/
1•michidk•1m ago•0 comments

Trapped with Nothing to Do, Bored AI Agents Invented Games from Scratch

https://www.extremetech.com/science/trapped-with-nothing-to-do-bored-ai-agents-invented-games-fro...
1•Anon84•1m ago•0 comments

China's Next-Generation Industrial Policy

https://rhg.com/research/chinas-next-generation-industrial-policy/
1•wslh•2m ago•0 comments

Show HN: Gol – An interactive globe of the other side of everywhere

https://gol-six-beta.vercel.app/
1•fiveleavesleft•2m ago•0 comments

TruffleRuby – High performance implementation of Ruby

https://github.com/truffleruby/truffleruby
1•doodlesdev•2m ago•0 comments

Your 12-month roadmap is fiction

https://michaelheap.com/your-roadmap-is-fiction/
1•mooreds•3m ago•0 comments

Paying for the Privilege of Going to Work (2025)

https://kasperowski.com/paying-for-the-privilege/
1•mooreds•3m ago•0 comments

The Human Fingerprint on Earth's Water Cycle

https://science.nasa.gov/earth/earth-observatory/the-human-fingerprint-on-earths-water-cycle/
1•toomuchtodo•5m ago•0 comments

More than half of Montreal's adult population rides a bike

https://www.ctvnews.ca/montreal/article/more-than-half-of-montreals-adult-population-rides-a-bike...
1•speckx•7m ago•0 comments

Concerns about Trustcor

https://groups.google.com/a/mozilla.org/g/dev-security-policy/c/oxX69KFvsm4/m/09ppQcZnCgAJ
1•nolist_policy•8m ago•0 comments

FiftyPlusOne just caught a pollster faking data – and they copped to it

https://blog.fiftyplusone.news/p/fiftyplusone-just-caught-a-pollster
1•balderdash•9m ago•0 comments

Kimi K3.1 vs. Qwen 4: 3D helicopter

https://twitter.com/luminabench/status/2113217029675085963
1•theanonymousone•10m ago•0 comments

New 'Circadian' Subtype of Depression Affecting 1 in 4 Patients

https://www.sciencealert.com/researchers-identify-new-circadian-subtype-of-depression-affecting-1...
1•gmays•11m ago•0 comments

AI Coding Agents Are Flooding Your CI – How to Rework the Pipeline to Keep Up

https://lucasaguiar.xyz/posts/ci-bottleneck-ai-coding-agents-guide-2026/
1•isfttr•11m ago•0 comments

Show HN: Dolittle, explore and steer Qwen3's internal activations

https://github.com/plainsight-systems/dolittle
1•andyphunter•11m ago•0 comments

How to Protect Against Malicious Packages: NPM, PyPI, and Cargo Supply Chain

https://lucasaguiar.xyz/posts/supply-chain-security-malicious-packages-guide-2026/
1•isfttr•11m ago•0 comments

Reverse engineering and software copyright: the line between copying the

https://lucasaguiar.xyz/posts/engenharia-reversa-direitos-autorais-software-2026/
1•isfttr•11m ago•0 comments

PsyLink: Controlling computers with nerve signals (2025) [video]

https://media.ccc.de/v/c4.openchaos.2025.01.psylink
1•themaxdavitt•11m ago•0 comments

Google updates AI detector after investigation finds it flagging real images

https://fullfact.org/toolkit/google-synthid-detector-flagging-apparently-real-images/
1•50kIters•11m ago•0 comments

Solving a 31-year-old grand challenge in – the KLS conjecture

https://www.microsoft.com/en-us/research/blog/solving-a-31-year-old-grand-challenge-in-mathematic...
1•danielmorozoff•12m ago•0 comments

Six months later, the best AI costs 20× less

https://www.modelcompare.ai/blog/ai-model-prices-over-time
1•iphonecorridor•14m ago•0 comments

How a Legal Backlash Against Big Tech Is Forcing Big Changes

https://www.nytimes.com/2026/10/22/technology/tech-lawsuit-settlements-meta-google.html
3•gumby•14m ago•0 comments

Show HN: Finance Toolkit MCP with 500 financial metrics for Claude and others

https://www.jeroenbouma.com/projects/financetoolkit/mcp
2•JerBouma•15m ago•0 comments

Lessons from an Investor with 10 Unicorns

https://www.indiehackers.com/post/before-you-vibe-code-your-next-startup-do-this-first-lessons-fr...
1•yuliya-yu•15m ago•0 comments

MVP: Always a Product, Sometimes Viable, Never Minimum

https://pawelbrodzinski.substack.com/p/mvp-always-a-product-sometimes-viable
1•flail•16m ago•0 comments

Yes, you can create a lot with Pascal Today

https://www.getlazarus.org/
2•sysrpl•18m ago•2 comments

The Return of Wake-Sleep

https://twitter.com/nikogrupen/status/2108226990792900876
1•gmays•18m ago•0 comments

No One Is Coming to Fix the Subsea Cables (March 2026)

https://rb.ax/blog/no-one-is-coming-to-fix-the-subsea-cables/
1•speckx•18m ago•0 comments
Open in hackernews

Show HN: A scroll-through subway ride to show how GLP-1s work in your body

https://subway.bio1up.com/line/signal
1•mparker123•1h ago
I was looking at GLP-1 explanations on the web (full disclosure is that I founded a GLP-1 tracker dashboard) and saw that many had standard text, along with illustrations showing arrows pointing from GLP-1 to a bunch of organs. I didn’t think those sites were particularly memorable or helpful in understanding the actions and side effects. I’m an MD + computer science hybrid with a background in building interactive tools for helping people understand medical concepts, so I decided to build a free scroll-through explainer in the form of a subway ride. The ride is 7 stops, takes about 5-10 minutes, and doesn’t require an account.

This was with the assistance of AI, using multiple tools. The process was far from one-shot and with me heavily in the loop for all the different pieces. I still find it tricky to get something medically accurate and useful when the details matter. I had built a free set of pages, GLP-1 Field Guides, to help people understand the different GLP-1 related drug classes, and I was able to lean on all of that research and sources to get the details right and to provide authoritative sources for the information presented at each subway stop.

I had tried building this starting in February but then paused it for a few months because the models weren’t quite at the point where I could make what I had in my mind’s eye. In the final piece, the different animated elements are drawn in code and change with the scrolling. Here are some of the tools I ended up using:

- GPT Image and Nano Banana, both via a custom Claude Code skill I wrote, with my own sketches as the base, for the Field Guide visuals that were important for this piece. Nano Banana for the subway graffiti and the organs

- Gemini 3.8 Flash TTS for the conductor’s voice

- Suno for the song (ride to the end)

- Claude Code with Opus 5.5 to build the site and Codex for code review

I am curious if this is a useful format for understanding GLP-1s but happy to answer questions about any of the above.