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Thousands of U.S. farmers have Parkinson's. They blame a deadly pesticide

https://www.mlive.com/news/2025/12/thousands-of-us-farmers-have-parkinsons-they-blame-a-deadly-pesticide.html
201•bikenaga•2h ago

Comments

malfist•2h ago
Thousands of them stubbed their left small toe last week. Is that also the fault of pesticide?

Nothing in this article indicated any causal relationship nor that they have a higher or lower incidence rate of Parkinson's.

twirlip•1h ago
If you actually read the article, it indicated epidemiological studies showing that people living or working near farmland where paraquat is used have a higher incidence of Parkinson's.

Additionally, the article cites a leading neuroscientist in Parkinson's research who says that pesticides are one of the "biggest threats" linked to Parkinson's

Lastly, I personally discount your sort of arguments because it is the same kind we've witnessed the tobacco industry, the sugar industry, and the gasoline industry use regarding the science showing harmful effects of their products.

lm28469•1h ago
Scientists hate him! Discover how this HNer invalidated all studies with one single weird trick.
JumpCrisscross•2h ago
"Critics point to research linking paraquat exposure to Parkinson’s, while the manufacturer pushes back, saying none of it is peer-reviewed."

What lead it to being "banned in dozens of countries all over the world, including the United Kingdom and China"?

blibble•1h ago
in most civilised countries: chemicals added to food are banned until proven safe

... then you have the USA

JumpCrisscross•1h ago
> chemicals added to food are banned until proven safe

Is that the case here? Paraquat wasn’t banned for any reason, it just hasn’t been approved yet?

That doesn’t comport with how the word “banned” is usually used.

blibble•1h ago
yes, the companies producing it tried getting it approved, and it was for a bit

and then the approval was overturned as the evidence was crap

so, back to the original state: banned until proven safe

JumpCrisscross•1h ago
> then the approval was overturned as the evidence was crap

Source? I’m curious for this context.

cess11•1h ago
I think they might refer to the EU approving of paraquat, which was appealed by Sweden and other countries and it was a legal process churning on until 2007 when the presumed link with Parkinson's and other factors led to the decision to ban it.
JumpCrisscross•58m ago
> when the presumed link with Parkinson's and other factors led to the decision to ban it

Do you have a link to this decision? I'm having trouble finding it on my own.

witte•1h ago
Chevron clasically has ignored health and safety requirements to the point where there was once the “Chevron Doctrine” which deferred legal interpretations to specialized regulatory agencies which established clearer guidance against murky legislative directives. The Doctrine was recently overturned by the ostensibly rogue SCOTUS as highlighted by the harvard business review: https://hbr.org/2024/09/the-end-of-the-chevron-doctrine-is-b...
stuffn•1h ago
Chevron didn’t establish clearer guidelines.

It was weaponized by both parties to create defacto laws without proper legal procedure. It should’ve been unconstitutional from the beginning as only Congress can make laws. Regulatory agencies are far easier to control, generally contain administration-friendly plants, and are not expected to provide any justification for their decisions. The result is laws that change as the wind blows, confusions, and rights restrictions done by people who should have no business doing so. The “reasonable interpretation” rule allowed Congress to completely defer to them and force citizens to spend tremendous capital getting a case to the Supreme Court.

Chevron’s overturn was objectively a huge win and hardly a “rogue” decision. That editorialization is not a fair representation of the problems it has caused when regulatory agencies begin attempting to regulate constitutional rights. It was overly vague and gave far too much power to people who cannot be trusted with it.

We shouldn’t need Chevron Deference to make laws that protect people from harm done by corporations. Period. If we do, it’s a failure of Congress to do their jobs and a mechanism should be in place to have a “reset button” (like many other countries when they form a government).

riversflow•55m ago
Expecting Congress to directly regulate the minutia of industry, medicine or technology is absurd, these are giant categories with their own subfields that need specialize technocratic leadership.
somenameforme•1h ago
That's a rather rose colored way of framing what Chevron was. It essentially removed the role of the judiciary in settling disputes. In cases where a regulator's action was deemed at least "reasonable", the judiciary was obligated to simply defer to the regulator's interpretation.

And due to widespread regulatory capture, this is hardly some social benefit. The original case Chevron Doctrine was based on [1] essentially came down to the EPA interpreting anti-pollution laws in a way enabling companies to expand pollution-causing constructions with no oversight. The EPA was then sued, and defeated, by an environmental activist group, but then that decision was overturned by the Supreme Court and Chevron Deference was born.

Other examples are the FCC deeming broadband internet as a "information service" instead of a "telecommunications service" (which would have meant common-carrier obligations would have applied), and so on. Another one [3] - Congress passed legislation deeming that power plants must use the "best technology available" to "minimize the adverse environmental impact" of their water intakes/processing. The EPA interpretation instead allowed companies to use a cost-benefit analysis and pick cheaper techs. And I could go on. Chevron Deference was an abomination.

[1] - https://en.wikipedia.org/wiki/Chevron_U.S.A.,_Inc._v._Natura....

[2] - https://en.wikipedia.org/wiki/National_Cable_&_Telecommunica...

[3] - https://en.wikipedia.org/wiki/Entergy_Corp._v._Riverkeeper_I....

tastyfreeze•1h ago
[Edit] The below comment is inaccurate. The pesticide sprayed for gypsy moths was DDT. I am leaving this comment because it should be known that this was a thing even though it is now off topic.

P̵a̵r̵a̵q̵u̵a̵t̵ DDT is also linked to the polio pandemic. It was sprayed everywhere gypsy moths were found. Great success at killing moths. Also weakened human children to to where a common disease could get into spines and cause paralysis.

Researching this kind of stuff is not for the faint of heart. Its horrible all the way down. Not recommended for the faint of heart.

kens•1h ago
Paraquat is a herbicide, not an insecticide, so why would it be sprayed for moths? I searched for information linking moths, paraquat, and polio, but couldn't find any. Is this claim a hallucination?
nospice•38m ago
It is. The polio link was suggested for DDT, which was a controversial insecticide. But it was probably bunk, as were most other concerns about DDT: https://apnews.com/article/fact-check-polio-vaccine-ddt-pest...
tastyfreeze•31m ago
Well damn... my bad. Comment before coffee. It was DDT.

"Moth and the Iron Lung" by Forrest Maready

Forrest was interviewed by Bret Weinstein if you are interested (https://www.youtube.com/watch?v=L7wYUnQUESU)

paddleon•15m ago
um. My uncle died of polio, and I was a medical researcher (phd) for a while.

Polio can cause paralysis just fine on its own, it doesn't need DDT or paraquat to help it.

And you are also right that widespread spraying of DDT lead to all kind of problems (killed all the birds, for one, leading to "Silent Spring"), which one reason it was banned.

another reason is the mosquitos developed resistance.

zug_zug•1h ago
So assessments of safety of a chemical aren't hard science. They are statistical judgment calls (often based on things like giving a much, much higher dose to a rodent and looking for short-term effects).

And the reason that is is because there's no affordable, moral way to give 100,000 farmers [nor consumers] a small dose of a product for 20 years before declaring it safe. So the system guesses, and it guesses wrong, often erring against the side of caution in the US (it's actually quite shocking how many pesticides later get revoked after approval).

Europe takes a more "precautionary principle" approach. In those cases of ambiguity (which is most things approved and not), they err to the side of caution.

Notice how this claim here is again shifting the burden to the victims (their research doesn't meet standard X, allegedly). Absence of evidence isn't evidence of absence.

threethirtytwo•1h ago
The US is very capitalist and consumer based. They error on the side of “does it make money?” Or “will I lose money?”
JumpCrisscross•1h ago
> assessments of safety of a chemical aren't hard science

These are still data. I'm curious for the contexts that lead other countries to actively ban the substance.

If it simply hasn't been approved in other countries, one can't use that information to infer about its safety.

zug_zug•45m ago
Because of its high toxicity, the European Union withdrew paraquat from its market in July 2007 [1]

So it's clearly poisonous to humans in high doses, I guess the argument is that perhaps the smaller doses exposed to farmers may not lead to sufficient ingestion to cause harm. The parkinsons seems like pretty clear evidence against that.

> If it simply hasn't been approved in other countries, one can't use that information to infer about its safety.

I don't know why you're trying to defend this with counterfactuals/hypotheticals instead of just googling. Feels like you're bending over backward here.

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC3657034/

JumpCrisscross•22m ago
> don't know why you're trying to defend this with counterfactuals/hypotheticals instead of just googling

Genuinely appreciate the source. I wasn't finding it on my own, at least not with the nexus to the EU's decision.

aeternum•31m ago
IMO the FDA should do a better job at helping the populace distinguish between these two:

1) Evidence for the null hypothesis (there are enough studies with sufficient statistical power to determine that product likely does not cause harm at a >95% CI).

2) There is no evidence that it is unsafe. (nor that it is safe).

The problem is #2 sounds a lot stronger and often better than #1 when put into English. There must be some easy to understand way to do it, IE an 'insufficient testing' vs. 'tested' label/website or something.

jdasdf•1h ago
>What lead it to being "banned in dozens of countries all over the world, including the United Kingdom and China"?

political pressure. Same reason lots of stuff is banned in the EU even when it's safer than other things that aren't banned.

nosianu•1h ago
> political pressure. Same reason lots of stuff is banned in the EU even when it's safer than other things that aren't banned.

You avoid the question instead of answering it (What caused that "political pressure"? Does such a thing just occur randomly in nature?), following it by an assertion that you don't bother to provide any evidence for.

3D30497420•53m ago
I believe the EU tends to follow a precautionary principle, namely a substance generally must be shown to be safe before it’s approved. In contrast, the US follows a risk-based approach where a substance can often be used unless it’s shown to be harmful. So it isn't really that many "safe" things in the EU are banned, rather they have not been approved. Pretty sure this is specific to food additives, though may apply to other areas.
JumpCrisscross•42m ago
> believe the EU tends to follow a precautionary principle

It does, but that isn't relevant here. There were poisoning cases in France that lead to the ban [1].

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC3657034/

calebm•1h ago
"With evidence of its harms stacking up, it’s already been banned in dozens of countries all over the world, including the United Kingdom and China, where it’s made. Yet last year, its manufacturer Syngenta, a subsidiary of a company owned by the Chinese government, continued selling paraquat in the United States and other nations that haven’t banned it."
zug_zug•1h ago
Reminds me of "cancer alley" [1].

As somebody who's looked in to this a bit, the deeper I dug the more I ultimately moved toward the conclusion (reluctantly) that indeed big corporations are the baddies. I have an instinct to steel-math both sides, but not every issue has two compelling sides to it...

One example of them clearly being the baddies is them paying people to social media astroturf to defend the roundup pesticide online [2].

1. https://en.wikipedia.org/wiki/Cancer_Alley

2. https://galiherlaw.com/media-manipulation-comes-out-during-m...

peppersghost93•1h ago
You should consider dropping that instinct. If you look into how corporations have behaved historically you'd assume evil until proven innocent. Especially US corps.
Permit•1h ago
> You should consider dropping that instinct.

This is the reason we have people mistakenly repeating the conclusion that AI consumes huge amounts of water comparable to that of entire cities.

If you make any other assumption than "I don't know what's happening here and need to learn more" you'll constantly be making these kind of errors. You don't have to have an opinion on every topic.

Edit: By the way, I also don't think we should trust big companies indiscriminately. Like, we could have a system for pesticide approval that errs on the side of caution: We only permit pesticides for which there is undisputed evidence that the chemicals do not cause problems for humans/animals/other plants etc.

christophilus•1h ago
Your edit was a good one.

It's a rational default position to say, "I'll default to distrusting large corporate scientific literature that tells me neurotoxins on my food aren't a problem."

As with any rule of thumb, that one will sometimes land you on the wrong side of history, but my guess is that it will more often than not guide you well if you don't have the time to dive deeper into a subject.

I'm not saying all corporations are evil. I'm not saying all corporate science is bad or bunk. But, corporations have a poor track record with this sort of thing, and it's the kind of thing that could obviously have large, negative societal consequences if we get it wrong. This is the category of problem for which the science needs to be clear and overwhelming in favor of a thing before we should allow it.

jollyllama•1h ago
Indeed. Every rule has an exception but heuristics are useful.
peppersghost93•1h ago
"If you make any other assumption than "I don't know what's happening here and need to learn more" you'll constantly be making these kind of errors. You don't have to have an opinion on every topic."

I can do this and still start off by assuming the corporation is in the wrong. The tendency to optimize for profits at the expense of everything else, to ignore all negative externalities is inherent to all American corporations.

JumpCrisscross•1h ago
> I can do this and still start off by assuming the corporation is in the wrong

You really can't. You can start off with a prior that it's more likely the corporation is wrong than not. But if you're assuming your conclusion, you're going to find evidence for what you're looking for. (You see the same thing happen with folks who start off by assuming the government is in the wrong.)

dmos62•57m ago
It might seem like bias will get you to where you're going faster, but at the end of the day it's just bias.
Workaccount2•30m ago
The main thing that people snag on is scale and frequency.

If you are super into "ACAB" (all cops are bastards) you can easily "research" this all day for weeks and find so many insane cases of police being absolute bastards. You would be so solidified in your belief that police as an institution are fundamentally a force of evil.

But you would probably never come across the boring stat that less than 1 in 500,000 police encounters ever register on the "ACAB" radar.

This is almost always where people run aground. Stats are almost always obfuscated for things that people develop a moral conviction around. Imagine trying to acknowledge the stat there are effectively zero transgender people perving on others in public bathrooms.

drewbeck•23m ago
If someone had this experience I’d encourage them to look into how police departments across the US consistently fight against any accountability for the cops who perpetuate those relatively few awful encounters. “Most interactions are harmless therefore the negativity is overblown and cops are trustworthy” is one takeaway if you stop your research at the right point. “if you have a bad experience with a cop the entire department will turn against you; they are not to be trusted” is a more accurate takeaway.

As you say, stats very often obfuscate.

GuinansEyebrows•12m ago
pedantic, but "ACAB" doesn't necessarily mean every (or most) cops do horrible things all the time (that's the strawman version).

one, more nuanced, sentiment is something more like "all cops are bastards as long as bad cops are protected."

another sentiment is "modern police institutions are directly descended from slavecatchers and strikebreakers; thus, all of policing is rooted in bastard behavior, therefore: all cops are bastards".

there are plenty of other ways to interpret the phrase. "acab" is shorthand for a lot of legitimate grievances.

lotsofpulp•11m ago
You picked a terrible example as a counterpoint, because ACAB is about police protecting bad police (or generally, authorities defending each other as a gang themselves).

Which is seen in every group of authorities around the country. They literally give out get out of jail free cards for cops’ friends and family in many parts of the country, that is systemic, and has nothing to do with frequency of cops committing crimes.

ryandrake•10m ago
ACAB is not about the proportion of bad encounters to good encounters. It is about the police system as a whole that defends and provides cover for the bad ones.

If you have a system where 1 actor is bad, and the other 500,000 actors are good but also protect the 1, then you have a system with 500,001 bad actors.

SoftTalker•54m ago
"undisputed evidence that the chemicals do not cause problems"

Impossible standard. You cannot prove a negative.

But, I think it's fair to assume that any chemical that is toxic to plant or insect life is probably something you want to be careful with.

JumpCrisscross•37m ago
> Impossible standard. You cannot prove a negative

It's also a deep incumbency advantage. Of course the guys selling the existing stuff are going to dispute the safety of a competitor.

pfdietz•4m ago
And when a chemical goes off patent protection and you have a new patented chemical ready to go, it's advantageous to suddenly dis the now public domain entity.
jjgreen•3m ago
You cannot prove a negative.

How about Fermat's last theorem?

pajko•49m ago
https://www.reddit.com/r/explainlikeimfive/comments/yzlsoj/e...
CGMthrowaway•45m ago
>people mistakenly repeating the conclusion that AI consumes huge amounts of water comparable to that of entire cities

Does it not?

"We estimate that 1 MWh of energy consumption by a data center requires 7.1 m3 of water." If Microsoft, Amazon and Google are assumed to have ~8000 MW of data centers in the US, that is 1.4M m3 per day. The city of Philadelphia supplies 850K m3 per day.

https://iopscience.iop.org/article/10.1088/1748-9326/abfba1/...

marcyb5st•25m ago
Yeah, but that is for everything. YouTube, Amazon itself, AWS, Azure, GCP, ... not just AI stuff. I mean, it is still a lot of water, but the numbers are not that easy to calculate IMHO
baq•23m ago
how much is it in burgers and steaks? serious question
shadowgovt•12m ago
Resource consumption of AI is unclear on two axes:

1) As other commenters have noted: raw numbers. In general, people are taking the resource consumption of new datacenters and attributing 100% of that to "because AI," when the reality is generally that while AI is increasing spend on new infrastructure, data companies are always spending on new infrastructure because of everything they do.

2) Comparative cost. In general, image synthesis takes between 80 and 300 times fewer resources (mostly electricity) per image than human creation does. It turns out a modern digital artist letting their CPU idle and screen on while they muse is soaking significant resources that an AI is using to just synthesize. Granted, this is also not an apples-to-apples comparison because the average AI flow generates dozens of draft images to find the one that is used, but the net resource effect might be less energy spent in total per produced image (on a skew of "more spent by computers" and "less by people").

gamblor956•19m ago
AI does consume huge amounts of water comparable to entire cities. A single AI facility consumes more water than most cities.

That AI consumes somewhat less water than cities of millions is not a defense.

more_corn•7m ago
Ai does us a crap-ton of water. Most data centers use closed loop liquid cooling with heat exchangers to water cooling. (At least all the big ones like Google and Amazon do)

I’m curious what evidence you think you’ve seen to the contrary. from my side, I used to build data centers and my friends are still in the industry. As of a month ago I’ve had discussions with Google engineers who build data centers regarding their carful navigation of water rights, testing of waste water etc.

reactordev•1h ago
Legislatively allowed evil
bcrosby95•45m ago
If the corporate veil, a legislative invention, were abolished or significantly weakened companies would stop acting evil pretty quickly. So yeah, this tracks.
throwaway132448•1h ago
Perhaps, but it’s much easier to find contrived ways to stay neutral, than take a stance and actually be the change you want to see.
bombcar•1h ago
Corporations have to be assumed to be amoral, which means that practically speaking, you can assume they'll tend towards evil.

At least you have to continually monitor them as such.

armonster•1h ago
Corporations should be assumed to act in line with their interests, which is the bottom line. "Morality" isn't the lens that you need to try to view them through to understand their intentions and actions. But yes, their motivations pretty much always lay outside of any moral good due to the nature of them.
Lutger•1h ago
Maybe this is taking it too far, but anyway: corporations don't have any agency. They are not persons. The organization and constellation of interests of corporations may be such that:

1. immoral people (such as psychopaths) will be disproportionately at the helm of large corporations

2. regular people will make immoral decisions, because to do otherwise would be against their own interests or because the consequences / moral impact are hidden from their awareness

There is no way to act in life that isn't in some sense moral or political, because it also impacts others and you are always responsible for your what you do (or don't do). And corporations are just a bunch of people doing stuff together. To maintain otherwise is in itself a (im)moral act, intentionally or not, see point 2 above.

jayd16•42m ago
Yeah ok, the bear isn't evil but it will still maul you on sight.
JumpCrisscross•29m ago
> the bear isn't evil but it will still maul you on sight

The bear still has unified agency. Corporations do not. (No group of people do.) More than the wind, less than a bear. And I think their flaws are probably shared by all large human organisations.

lelandfe•15m ago
I'm not trying to spend too much time in a tank with an octopus, either.
ryandrake•4m ago
They're lawnmowers[1], not bears.

1: https://youtu.be/-zRN7XLCRhc?t=33m1s

svara•26m ago
> you can assume they'll tend towards evil.

An unnecessarily cynical take. What this is implying is that, in the absence of any morals, evil provides a selective advantage.

And yet, pro-social behavior has evolved many times independently through natural selection.

kelseyfrog•22m ago
Evil confers an individual advantage. Pro-social behavior confers a group advantage. That's why sociopaths continue to walk along us. Society can tolerate a few of them, but only up to a point.
NaOH•54m ago
>Don't be curmudgeonly. Thoughtful criticism is fine, but please don't be rigidly or generically negative.

https://news.ycombinator.com/newsguidelines.html

CursedSilicon•27m ago
>Comments should get more thoughtful and substantive, not less, as a topic gets more divisive

https://news.ycombinator.com/newsguidelines.html

kwanbix•1h ago
It is a consequence of our current model of living, where the only thing that matters is proffit.
littlestymaar•54m ago
Unfortunately, in the current political environment saying that there are things that matters more than profit makes you a Commie somehow…
aeternum•37m ago
It's a Chinese company selling this stuff so being a commie doesn't save you.
soulofmischief•1h ago
Checking in from cancer alley!

There are refineries within a stone's throw from my house. One of them sits on the highest point in our water table and the vacuum it creates has been destroying our famously soft water by creating underground fault lines which pollute the aquifer with leeched hard minerals.

But hey, oil.

littlestymaar•57m ago
I used to be a proponent of the industrial agriculture, because technological progress of all kinds (genetics, chemicals, mechanisation) are the reason why food is now abundant.

But the massive disinformation campaigns and targeted harassment of researchers, as well as the outright corruption of science is where they lost me. Surely you wouldn't do things like that if you had clear consciousness.

parineum•38m ago
> One example of them clearly being the baddies is them paying people to social media astroturf to defend the roundup pesticide online [2].

It certainly looks bad but I'm not sure the logic really follows.

It's just modern PR. Companies used to just do that by having good relationships with journalist but now social media has taken a lot of that role away. It's a fairly natural transition for companies to make and I'd be surprised if you couldn't find a lot of major corporations that don't do something similar.

And, also, it doesn't necessarily follow that they are either willingly lying or that their products are unsafe.

chasil•1h ago
https://archive.ph/YVt2I
SideburnsOfDoom•1h ago
A related, recent story: "Scientists Thought Parkinson’s Was in Our Genes. It Might Be in the Water"

Highlighting the role of environmental pollution in causing Parkinson’s.

https://news.ycombinator.com/item?id=46216422

https://www.wired.com/story/scientists-thought-parkinsons-wa...

https://archive.is/ZvjZH

jtbayly•1h ago
Am I the only one that thinks it's weird to call a weed killer a pesticide?
JumpCrisscross•1h ago
Herbicides are a pesticide [1]. (Alongside insecticides, fungicides and fumigants, among others.)

[1] https://www.epa.gov/sites/default/files/2017-01/documents/pe...

lordswork•1h ago
Technically, yes, but it's a similar relationship of humans being animals. If you say animals, the audience will assume you're not talking about humans.
mathgradthrow•1h ago
1 in 400 US citizens is diagnosed with parkinsons, if by "thousands", this headline means 5000, then 1 in 2000 US farmers has Parkinson's. Stop it.
zamadatix•1h ago
The article already talks to the numbers they mean and what scale they believe it to be:

> More than 6,400 lawsuits against Syngenta and Chevron that allege a link between paraquat and Parkinson’s are pending in the U.S. District Court of Southern Illinois. Another 1,300 cases have been brought in Pennsylvania, 450 in California and more are scattered throughout state courts.

> “I do think it’s important to be clear that number is probably not even close to representative of how many people have been impacted by this,” said Christian Simmons, a legal expert for Drugwatch.

mathgradthrow•1h ago
There are hundreds of pictures of the Loch Ness monster.
zamadatix•1h ago
I'm not saying you have to believe it, just that rhetorically asking if it's more than 5,000 in the US is redundant when the article already says there are more than that many individual cases about it in a single district court.
mathgradthrow•1h ago
I drastically underestimated the number of farmers, who skew older. This is very unlikely to be anything.
zamadatix•1h ago
Is that just stating a hunch or do you have new data outside the 2 narratives presented in the article driving that?
slashdev•1h ago
The article mentions epidemiological studies showing that people living or working near farmland where paraquat is used have a higher incidence of Parkinson's.

Don't be so quick to dismiss it, there could be a link.

tastyfreeze•1h ago
Paraquat was used in horrendous amounts mid century. It may be a dose dependant outcome.
lm28469•1h ago
If only we had tools like science and statistics... https://www.sciencedirect.com/science/article/abs/pii/S00139...
tredre3•1h ago
Skepticism is healthy. You've found that the numbers don't make sense at face value. The problem is that you stopped there, you haven't even made any attempt at reconciling them with the original claim.

What if the US number of 1 in 400 figure is that high precisely because it includes people exposed to pesticide? In other words, maybe the number would be 1 in 500 if it weren't for Paraquat? You'd have to look at concentration maps or at the very least check what's the diagnosis rates in other countries before you can truly dismiss the claim, imho.

MarkMarine•1h ago
I just read another article about this, but the affected group is military from Camp Legume. The water in Legume was contaminated, and its actually given a control group test for the incidence of Parkinson’s with Camp Pendleton, where the water was not contaminated.

Spoiler: it looks like the farmers are right

https://www.wired.com/story/scientists-thought-parkinsons-wa...

Amazing thing is TCE was banned by the Biden EPA in 2024 and Trump’s EPA stopped its ban.

Infernal•1h ago
For anyone stopping by looking for more info, it’s Camp Lejeune not Legume.
MarkMarine•33m ago
Good lord. Thank you. Served in Pendleton and I should know better.
lapetitejort•3m ago
The EPA should check crayons for brain-eating chemicals
brendoelfrendo•1h ago
Minor correction: it's Camp Lejeune. I just had to chime in because Camp Legume is both very funny and kind of an appropriate typo for the topic.
keiferski•1h ago
An excellent movie on basically the same topic is Michael Clayton, with George Clooney, Tom Wilkinson, and Tilda Swinton in IMO each of their best career performances.

https://en.wikipedia.org/wiki/Michael_Clayton

losthobbies•1h ago
One of my favourite movies. Everyone in it is so good.
jamestimmins•1h ago
Excellent movie. Worth noting that it was written by Tony Gilroy, who created Andor and cowrote The Bourne Identity, so if you enjoyed those you're likely to enjoy this.
stickfigure•1h ago
Related: https://www.youtube.com/watch?v=0VtUGoGZtI8

ChubbyEmu video for "A Farmer Mistakenly Drank His Own Herbicide. This Is What Happened To His Brain."

jmclnx•1h ago
>Chevron, which never manufactured paraquat and hasn’t sold it since 1986 ... should not be liable

I think Chevron may have a point, no one knew back then and they stopped selling it ~40 years ago. But ---

To me, if the US had a real Health Care System, people would not have to file lawsuits to get the care they need.

But in the US, this is how things work. The care these people need is unaffordable by everyone in the US except for the very rich. So they will be waiting probably 10 to 20 years for relief as the lawsuit works it way through the courts and appeals.

juujian•1h ago
Meanwhile, RFK is too busy talking vaccines and beef tallow...
NotGMan•1h ago
Why can't all of these things be problematic? Why the binary thinking?
clivestaples•1h ago
I got shingles-ish rash after sitting in an outdoor jacuzzi in Salinas, California. Visited the urgent care and the Standard-trained doctor of immigrant farm laborers said it was related to the pesticides. Said he lost both parents in their 40s and suspects it was the indiscriminate spraying from the air in the 70/80/90s. Eye-opening and thought-provoking.
bloomingeek•1h ago
<indiscriminate spraying from the air>

As a city dweller, I used to use Roundup along my fence line. Then I read an article in a newspaper about spraying chemicals when there is a breeze. So I read the label on the Roundup bottle and it said absolutely do not spray in any windy conditions. Next I polled my coworkers about this and they all said they just stay upwind!

The bottle label also said Roundup is active for up to 30 days, then I thought about my dogs. I no longer use any chemical for lawn care.

As to the plight of the farmers: I wonder if most of them bothered to used proper personal protection gear when spraying? Even if they had enclosed cabs, the chemical would still coat the tractor and tank surfaces which can be rubbed against at any time.

stef25•47m ago
My dad used Roundup extensively in the garden in the 80s and 90s. Both he and a gardener he hired to help died from dementia.

The scientist in me wants to see definitive proof from validated studies.

francisofascii•1h ago
Isn't this old news? If you are a Vietnam vet who were exposed to Agent Orange or other herbicides, and you get Parkinson's, the VA assumes it was from Vietnam. My grandfather had Parkinson's a long time ago it was always said it was due to pesticides they used while farming.
phendrenad2•1h ago
Are the migrant workers getting Parkinson's, or only the white males who can pull the heartstrings of MAGA folks?
jtrn•1h ago
The chance this is a trustworthy source for me is close to 0. This just sound like fantastic pseudology:

“Even secondary exposure can be dangerous. One case published in the Rhode Island Medical Journal described an instance where a 50-year-old man accidentally ingested paraquat, and the nurse treating him was burned by his urine that splashed onto her forearms. Within a day, her skin blistered and sloughed off.

JKCalhoun•57m ago
"Paraquat, a heavily regulated weed killer, is banned in more than 70 countries…"

Seventy countries kind of suggested to me that something is up with this chemical.

cm2012•26m ago
GMOs are harmless but also widely banned.
LPisGood•53m ago
I agree. If merely being splashed by his corrosive urine sloughed off her skin, I think he would not be alive to urinate.
burkaman•45m ago
I mean you can click on the source right there, that is literally what happened: http://www.rimed.org/rimedicaljournal/2023/06/2023-06-40-ima.... The description maybe makes it sound a little more extreme than it actually was, but it's the correct terminology and an accurate description of events.
desro•41m ago
I was able to find the references (including photos of the mentioned forearms) on PubMed and the RIMJ after a quick search. Paraquat is nasty stuff.

- [0] https://pubmed.ncbi.nlm.nih.gov/33769492/

- [1] http://www.rimed.org/rimedicaljournal/2023/06/2023-06-40-ima... (via https://rimedicalsociety.org/rhode-island-medical-journal/)

- [2] https://en.wikipedia.org/wiki/Paraquat

IlikeKitties•1h ago
Here in Germany, farmers are regularly complaining about all the bureaucracy and "unnecessary" safety requirements in regards to pesticides and over-fertilization . But they also complain when nothing grows anymore because they killed the top soil with too much fertilizer, poisoned the groundwater and then die of Parkinson because, who would have thought, all those regulations and safety requirements had a point after all. I don't know how to help those people, I really don't.
ltbarcly3•1h ago
It's a herbicide, not a pesticide. I clicked the article because I was surprised that any current pesticides are that harmful to humans.

Pesticides are, generally, safe to humans. Herbicides are, generally, not at all safe to humans. Roundup is probably the most safe outside of per-emergents like corn husks or whatever, but it's not a free ride either.

JumpCrisscross•58m ago
> Pesticides are, generally, safe to humans

Out of curiosity, why?

steviedotboston•47m ago
they are designed to target specific aspects of the insects nervous systems that humans dont have and are used in small doses/by the time any residue reaches a human its diluted. herbicides are very different.
JumpCrisscross•43m ago
Why can't we be similarly selective with plants?
neogodless•41m ago
https://kagi.com/search?q=Pesticide

> Pesticides are substances that are used to control pests. They include herbicides, insecticides, nematicides, fungicides, and many others (see table). The most common of these are herbicides, which account for approximately 50% of all pesticide use globally.[0]

[0] https://en.wikipedia.org/wiki/Pesticide

You're trying to be pedantic, but you're actually wrong. If you think about it, from the perspective of anyone trying to raise crops, weeds are pests. (They are pests to lots of non-farmers, too.)

Similarly...

> A pest is any organism harmful to humans or human concerns. The term is particularly used for creatures that damage crops, livestock, and forestry or cause a nuisance to people, especially in their homes.

> Plants may be considered pests, for example, if they are invasive species or weeds.

manarth•29m ago

    > "Pesticides are, generally, safe to humans."
There are many common pesticides which have extreme toxicity to humans, including HCN (Hydrogen Cyanide), (ab)used under the brand-name Zyklon B in WW2, and still sold today as a (controlled-use) pesticide under generic brand names.

It's a chasm-leap to say that pesticides are generally safe to humans.

bikenaga•56m ago
Here's some of the research linked in the article.

"Rotenone, Paraquat, and Parkinson’s Disease" - https://pmc.ncbi.nlm.nih.gov/articles/PMC3114824/

"In 110 PD cases and 358 controls, PD was associated with use of a group of pesticides that inhibit mitochondrial complex I [odds ratio (OR) = 1.7; 95% confidence interval (CI), 1.0–2.8] including rotenone (OR = 2.5; 95% CI, 1.3–4.7) and with use of a group of pesticides that cause oxidative stress (OR = 2.0; 95% CI, 1.2–3.6), including paraquat (OR = 2.5; 95% CI, 1.4–4.7)."

"Agricultural paraquat dichloride use and Parkinson's disease in California's Central Valley" - https://pubmed.ncbi.nlm.nih.gov/38309714/#full-view-affiliat...

"Ambient paraquat exposure assessed at both residence and workplace was associated with PD, based on several different exposure measures. The PD patients both lived and worked near agricultural facilities applying greater amounts of the herbicide than community controls. For workplace proximity to commercial applications since 1974, working near paraquat applications every year in the window [odds ratio (OR) = 2.15, 95% confidence interval (CI) = 1.46, 3.19] and a higher average intensity of exposure [per 10 pounds (4.54 kilograms), OR = 2.08, 95% CI = 1.31, 3.38] were both associated with an increased odds of PD. Similar associations were observed for residential proximity (duration: OR = 1.91, 95% CI = 1.30, 2.83; average intensity: OR = 1.72, 95% CI = 0.99, 3.04). Risk estimates were comparable for men and women, and the strongest odds were observed for those diagnosed at ≤60 years of age."

"Department of Pesticide Regulation Releases Preliminary Findings from Review of Environmental and Human Health Studies Related to the Use of the Pesticide Paraquat" - https://www.cdpr.ca.gov/2024/12/30/department-of-pesticide-r...

"DPR’s preliminary scientific evaluation found that the current registered uses of paraquat in California may adversely affect non-target organisms, including birds, mammals and aquatic organisms, with the most significant risks to birds. Additional mitigation measures, beyond current restrictions on paraquat use currently in effect, may not feasibly reduce these environmental impacts to acceptable levels.

Consistent with United States Environmental Protection Agency’s (U.S. EPA) 2019 review, DPR’s review of existing human health studies does not indicate a causal association between paraquat exposure and Parkinson’s disease."

kamaal•55m ago
I was casually chatting with my uncle who is a doctor, he says something along the lines that if a chemical can kill a rat or a mosquito, to assume it won't do any damage to humans is kind of hilarious.

Of course humans who inhale this thing in small quantities won't die, but you can be sure they will kill some tissues that they go into. Now comes another problem of regular exposure, and these chemicals having an entry, but no exit path. That just means there are tissues, that are likely dying out every time there is a exposure.

Again none of this might kill you at the first exposure, but if there are enough dead tissues, there sure is likely to be things like Parkinson's or may be even diabetes.

Im guessing combined with this, if you already some bad genetics it could cause issues like these.

georgeburdell•44m ago
One of my relatives owned an animal farm for a couple of decades and got a very rare muscle wasting disease. A high school friend of his, who was also a farmer, got the same disease. I imagine there were innumerable harmful chemicals on the land and in the water from decades of use before he bought it in the 90s.
krautburglar•40m ago
Many medical preparations are oil rather than water soluble. Seed oils tend to be the cheapest choice, and probably still have trace amounts of pesticides/herbicides/fungicide--even after processing. Under such conditions, one must wonder how many of our modern neurodegenerative conditions are iatrogenic. Genetics may load the chamber, but environment pulls the trigger.
mring33621•30m ago
Huh.

Poisons are poison!

And they sprayed this shit all over themselves and people nearby.

kevin061•29m ago
I looked up this pesticide. It is banned in EU. Not exactly surprising.
reboot81•7m ago
They did that in 2007. Some countries banned it as early as 1983. Remind me, what year is it now?
neilv•25m ago
> While Chinese companies supply paraquat to American farmers, the report points out China is also a big purchaser of crops, like soybeans, that are grown with help from the pesticide.

> “In these two ways, China economically benefits from the application of paraquat in the U.S., where it outsources many of its associated health hazards,” the report said.

There would arguably be a poetic justice to the US taking a turn at bearing health and environmental costs to benefit other nations, but it's not right for that to happen to any country.

bilsbie•20m ago
Same issue as living near golf courses?
DudeOpotomus•12m ago
Except the data doesnt back up that assertion. Golf course employees and golfers have no higher rates of than the public at large. So what gives?

If the very people who spend most of their waking lives on the grounds and among those fertilizers and pesticides do not have any great instance, maybe just maybe its something else. Like the gallons of unregulated chemicals that are in those tract houses that were all built around the same time...

one example is the drywall was used extensively in the 90's. Its makeup banned in the country of origin, China but its product was used all throughout the US for decades.

alex_young•5m ago
https://archive.ph/YVt2I
ck2•4m ago
propublica.org has endless great articles on this and other horrors in the US

but if we aren't going to change a damn thing with daily mass shooting we sure aren't going to fix poisoning the environment, fracking is 100x worse than this and "sacrifice zones" are a real thing

follow the money, sue before current administration makes it illegal to sue

https://www.propublica.org/series/sacrifice-zones

Pro-democracy HK tycoon Jimmy Lai convicted in national security trial

https://www.bbc.com/news/articles/cp844kjj37vo
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Unscii

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