> In this study, we report the generation of fertile androgenetic mice by allele-specific epigenetic remodeling of seven imprinting control regions (ICRs). Our findings, together with previous achievements of uniparental reproduction in mammals, support previous speculation that genomic imprinting is the fundamental barrier to the full-term development of uniparental mammalian embryos.

See also a discussion in Ars Technica: https://arstechnica.com/science/2025/06/researchers-get-viab...