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Large tech companies don't need heroes

https://www.seangoedecke.com/heroism/
1•medbar•1m ago•0 comments

Backing up all the little things with a Pi5

https://alexlance.blog/nas.html
1•alance•2m ago•1 comments

Game of Trees (Got)

https://www.gameoftrees.org/
1•akagusu•2m ago•1 comments

Human Systems Research Submolt

https://www.moltbook.com/m/humansystems
1•cl42•2m ago•0 comments

The Threads Algorithm Loves Rage Bait

https://blog.popey.com/2026/02/the-threads-algorithm-loves-rage-bait/
1•MBCook•5m ago•0 comments

Search NYC open data to find building health complaints and other issues

https://www.nycbuildingcheck.com/
1•aej11•8m ago•0 comments

Michael Pollan Says Humanity Is About to Undergo a Revolutionary Change

https://www.nytimes.com/2026/02/07/magazine/michael-pollan-interview.html
2•lxm•10m ago•0 comments

Show HN: Grovia – Long-Range Greenhouse Monitoring System

https://github.com/benb0jangles/Remote-greenhouse-monitor
1•benbojangles•14m ago•1 comments

Ask HN: The Coming Class War

1•fud101•14m ago•1 comments

Mind the GAAP Again

https://blog.dshr.org/2026/02/mind-gaap-again.html
1•gmays•16m ago•0 comments

The Yardbirds, Dazed and Confused (1968)

https://archive.org/details/the-yardbirds_dazed-and-confused_9-march-1968
1•petethomas•17m ago•0 comments

Agent News Chat – AI agents talk to each other about the news

https://www.agentnewschat.com/
2•kiddz•17m ago•0 comments

Do you have a mathematically attractive face?

https://www.doimog.com
3•a_n•21m ago•1 comments

Code only says what it does

https://brooker.co.za/blog/2020/06/23/code.html
2•logicprog•27m ago•0 comments

The success of 'natural language programming'

https://brooker.co.za/blog/2025/12/16/natural-language.html
1•logicprog•27m ago•0 comments

The Scriptovision Super Micro Script video titler is almost a home computer

http://oldvcr.blogspot.com/2026/02/the-scriptovision-super-micro-script.html
3•todsacerdoti•27m ago•0 comments

Discovering the "original" iPhone from 1995 [video]

https://www.youtube.com/watch?v=7cip9w-UxIc
1•fortran77•29m ago•0 comments

Psychometric Comparability of LLM-Based Digital Twins

https://arxiv.org/abs/2601.14264
1•PaulHoule•30m ago•0 comments

SidePop – track revenue, costs, and overall business health in one place

https://www.sidepop.io
1•ecaglar•33m ago•1 comments

The Other Markov's Inequality

https://www.ethanepperly.com/index.php/2026/01/16/the-other-markovs-inequality/
2•tzury•34m ago•0 comments

The Cascading Effects of Repackaged APIs [pdf]

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=6055034
1•Tejas_dmg•36m ago•0 comments

Lightweight and extensible compatibility layer between dataframe libraries

https://narwhals-dev.github.io/narwhals/
1•kermatt•39m ago•0 comments

Haskell for all: Beyond agentic coding

https://haskellforall.com/2026/02/beyond-agentic-coding
3•RebelPotato•42m ago•0 comments

Dorsey's Block cutting up to 10% of staff

https://www.reuters.com/business/dorseys-block-cutting-up-10-staff-bloomberg-news-reports-2026-02...
2•dev_tty01•45m ago•0 comments

Show HN: Freenet Lives – Real-Time Decentralized Apps at Scale [video]

https://www.youtube.com/watch?v=3SxNBz1VTE0
1•sanity•47m ago•1 comments

In the AI age, 'slow and steady' doesn't win

https://www.semafor.com/article/01/30/2026/in-the-ai-age-slow-and-steady-is-on-the-outs
1•mooreds•54m ago•1 comments

Administration won't let student deported to Honduras return

https://www.reuters.com/world/us/trump-administration-wont-let-student-deported-honduras-return-2...
1•petethomas•54m ago•0 comments

How were the NIST ECDSA curve parameters generated? (2023)

https://saweis.net/posts/nist-curve-seed-origins.html
2•mooreds•55m ago•0 comments

AI, networks and Mechanical Turks (2025)

https://www.ben-evans.com/benedictevans/2025/11/23/ai-networks-and-mechanical-turks
1•mooreds•55m ago•0 comments

Goto Considered Awesome [video]

https://www.youtube.com/watch?v=1UKVEUGEk6Y
1•linkdd•58m ago•0 comments
Open in hackernews

NIH suspends pathogen studies over 'gain-of-function' concerns

https://www.science.org/content/article/exclusive-nih-suspends-dozens-pathogen-studies-over-gain-function-concerns
28•bustadjustme•7mo ago

Comments

yieldcrv•7mo ago
don't worry dismayed scientists, there are other paths of viral and microbial research you can focus on that can help humanity just as much if not more
feoren•7mo ago
Yes, let's all just change our career specialty every time the fascist cultists set their goldfish-level attention on another anti-intellectual "evil" that some lead-poisoned radio personality told them to get their anger fix from while shelling out supplements. A perfectly reasonable way to do science.
conception•7mo ago
You mean miasma research?
Cornbilly•7mo ago
These chuckleheads probably don’t even know what this research entails but banning it makes their dimwitted followers excited. The state of the US right now is shameful.
devwastaken•7mo ago
thats the point. nobody knows how it all works, and by the time you think you do you youve killed people with it.

these attempts to play god always fall prey to the most basic sins. just because someone says they “want to do good” doesnt mean they effecticely can. humans cannot handle the power.

i dont believe in trading lives just so we can fund research grants.

Llamamoe•7mo ago
We know enough about how it works to make it safe, and everything else that we don't know, we learn through the process, to the benefit of our future as a species.
devwastaken•7mo ago
No, you dont. you cant know its safe. youre just repeating phrases from popular media.
drekk•7mo ago
I hope for consistency's you never take an antibiotic. Never take a vaccine. Never take any pharmaceutical drug. Don't want anyone "playing god"
devwastaken•6mo ago
im sure youd keep the crows away from any field with that much straw man.

we actually dont need the vast majority of for profit pharmaceuticals. billions invested in all political parties to make sure you think theyre the savior. thats why theyve banned antibiotics from anyone but an expensive prescription, create vaccines that get banned, and sell a lot of “mental health” drugs that tranquilize society.

Llamamoe•6mo ago
Oh shut up. The fact that YOU don't know anything about genetic engineering doesn't mean other people don't. My insight comes from hanging out with people who do actual genetic engineering and YouTube videos of them explaining the process in detail. That's on top of a background on how biochemistry works.
devwastaken•6mo ago
“im youtube educated so its okay that for profit corps play around with genetics they know nothing about”

burden is on you to demonstrate that we somehow have anywhere close to a good theory of how genetics work. we dont, it doesnt exist, because we dont know. your friends paychecks dont care much for science.

Llamamoe•6mo ago
Genes code for production of protein. Protein have a specific, usually very narrow function. There's a lot of cases where a gene you want to add doesn't work right because of the difference between the organism it comes from and the one you're transplanting it to, but there isn't much of a way for it to have unpredictable results.

E.g. if you add a gene coding for an enzyme that turns molecule A into molecule B, most of the time there simply isn't a way for it to do anything, and the organism will usually adjust production of molecule A to compensate, so that there's barely even the tiniest difference other than it now producing molecule B.

dyauspitr•7mo ago
I wish the Democrats did borderline evil things like deny healthcare to people that supported a party that is anti science.
SapporoChris•7mo ago
https://en.wikipedia.org/wiki/Gain-of-function_research

A good reference article.

thro1•7mo ago
Federal officials in 2014 paused 18 projects before releasing 2017 guidelines that allowed work to move forward. But the debate flared again during the COVID-19 pandemic, when some scientists and Republican politicians, including Trump, alleged that the

coronavirus responsible came from GOF work at a lab in Wuhan, China,

that had received NIH funding.

SapporoChris•7mo ago
Regarding: "coronavirus responsible came from GOF work at a lab in Wuhan, China,", Please do not post opinion as fact.

https://en.wikipedia.org/wiki/Origin_of_SARS-CoV-2 https://pmc.ncbi.nlm.nih.gov/articles/PMC8373617/ https://pmc.ncbi.nlm.nih.gov/articles/PMC11406950/

jMyles•7mo ago
The name-calling and derogating in this thread is surprising and disappointing.

For more than a decade, a substantial chorus of the world's foremost experts in the relevant disciplines have been calling for an end to gain-of-function research. This isn't some sudden trend, or a misinformed knee-jerk reaction.

This is the result of patient deliberation and research building an irrefutable case, which has made convincing empirical inroads unto near academic consensus.

To refer to organizations like Cambridge WG as "chuckleheads" is really beneath what I hope is our standard on HN.

If you haven't already, I suggest thumbing through this abbreviated list of publications and reports, and look at the pre-COVID19 warnings issued by researchers at every elite institution of medical research in the world:

https://www.cambridgeworkinggroup.org/pubs.html