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The next frontier in weight-loss drugs: one-time gene therapy

https://www.washingtonpost.com/health/2026/01/24/fractyl-glp1-gene-therapy/
1•bookofjoe•2m ago•1 comments

At Age 25, Wikipedia Refuses to Evolve

https://spectrum.ieee.org/wikipedia-at-25
1•asdefghyk•5m ago•2 comments

Show HN: ReviewReact – AI review responses inside Google Maps ($19/mo)

https://reviewreact.com
1•sara_builds•5m ago•0 comments

Why AlphaTensor Failed at 3x3 Matrix Multiplication: The Anchor Barrier

https://zenodo.org/records/18514533
1•DarenWatson•6m ago•0 comments

Ask HN: How much of your token use is fixing the bugs Claude Code causes?

1•laurex•10m ago•0 comments

Show HN: Agents – Sync MCP Configs Across Claude, Cursor, Codex Automatically

https://github.com/amtiYo/agents
1•amtiyo•10m ago•0 comments

Hello

1•otrebladih•12m ago•0 comments

FSD helped save my father's life during a heart attack

https://twitter.com/JJackBrandt/status/2019852423980875794
2•blacktulip•14m ago•0 comments

Show HN: Writtte – Draft and publish articles without reformatting, anywhere

https://writtte.xyz
1•lasgawe•16m ago•0 comments

Portuguese icon (FROM A CAN) makes a simple meal (Canned Fish Files) [video]

https://www.youtube.com/watch?v=e9FUdOfp8ME
1•zeristor•18m ago•0 comments

Brookhaven Lab's RHIC Concludes 25-Year Run with Final Collisions

https://www.hpcwire.com/off-the-wire/brookhaven-labs-rhic-concludes-25-year-run-with-final-collis...
2•gnufx•20m ago•0 comments

Transcribe your aunts post cards with Gemini 3 Pro

https://leserli.ch/ocr/
1•nielstron•24m ago•0 comments

.72% Variance Lance

1•mav5431•25m ago•0 comments

ReKindle – web-based operating system designed specifically for E-ink devices

https://rekindle.ink
1•JSLegendDev•27m ago•0 comments

Encrypt It

https://encryptitalready.org/
1•u1hcw9nx•27m ago•1 comments

NextMatch – 5-minute video speed dating to reduce ghosting

https://nextmatchdating.netlify.app/
1•Halinani8•28m ago•1 comments

Personalizing esketamine treatment in TRD and TRBD

https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1736114
1•PaulHoule•29m ago•0 comments

SpaceKit.xyz – a browser‑native VM for decentralized compute

https://spacekit.xyz
1•astorrivera•30m ago•0 comments

NotebookLM: The AI that only learns from you

https://byandrev.dev/en/blog/what-is-notebooklm
2•byandrev•30m ago•1 comments

Show HN: An open-source starter kit for developing with Postgres and ClickHouse

https://github.com/ClickHouse/postgres-clickhouse-stack
1•saisrirampur•31m ago•0 comments

Game Boy Advance d-pad capacitor measurements

https://gekkio.fi/blog/2026/game-boy-advance-d-pad-capacitor-measurements/
1•todsacerdoti•31m ago•0 comments

South Korean crypto firm accidentally sends $44B in bitcoins to users

https://www.reuters.com/world/asia-pacific/crypto-firm-accidentally-sends-44-billion-bitcoins-use...
2•layer8•32m ago•0 comments

Apache Poison Fountain

https://gist.github.com/jwakely/a511a5cab5eb36d088ecd1659fcee1d5
1•atomic128•34m ago•2 comments

Web.whatsapp.com appears to be having issues syncing and sending messages

http://web.whatsapp.com
1•sabujp•34m ago•2 comments

Google in Your Terminal

https://gogcli.sh/
1•johlo•35m ago•0 comments

Shannon: Claude Code for Pen Testing: #1 on Github today

https://github.com/KeygraphHQ/shannon
1•hendler•36m ago•0 comments

Anthropic: Latest Claude model finds more than 500 vulnerabilities

https://www.scworld.com/news/anthropic-latest-claude-model-finds-more-than-500-vulnerabilities
2•Bender•40m ago•0 comments

Brooklyn cemetery plans human composting option, stirring interest and debate

https://www.cbsnews.com/newyork/news/brooklyn-green-wood-cemetery-human-composting/
1•geox•40m ago•0 comments

Why the 'Strivers' Are Right

https://greyenlightenment.com/2026/02/03/the-strivers-were-right-all-along/
1•paulpauper•42m ago•0 comments

Brain Dumps as a Literary Form

https://davegriffith.substack.com/p/brain-dumps-as-a-literary-form
1•gmays•42m ago•0 comments
Open in hackernews

Brain drug: The deadliest "addiction" isn't a drug. It's something much worse

https://slate.com/life/2025/07/drug-brain-addiction-revenge-public-health-death.html
23•DocFeind•6mo ago

Comments

drooby•6mo ago
"When I read the story to a group of about 100 psychiatrists at an American Psychiatric Association convention in New York City and asked them what punishment Billy should receive, the most popular suggestion was that he should be locked in a cage with vicious dogs and torn to pieces."

I come across info bits like this every once in a while and I can't help be think... were they really answering the question truthfully, and just having a little laugh to themselves? Or, are we really this close to reverting to midieval behavior if our modern justice system crumbles

yesfitz•6mo ago
I wonder how this works/worked from an evolutionary perspective. Are vengeful people effective enforcers of tribal norms and customs? It would be a good deterrent to not cross someone if you knew they would destroy themselves to destroy you.

Still, one doesn't have to look far to find talking heads who will happily tell you that some group of people has slighted you and that you need to respond (by voting for [X]). So even if vengefulness is helpful, and even if forgiveness is the answer for unhelpful vengefulness, is there any way to keep it from being hijacked at scale?

Is it religion?

BizarroLand•6mo ago
I think it's mindfulness.

You can find this in religion, or generic spirituality, or meditation, or any number of activities. Putting in the effort to be aware of yourself in the moment, in your mental context, and in the context of the group you find yourself in, your place in society and in the world, and where you are now and where you want to be before you shuffle off the mortal coil, all of these things are important and matter.

Of course, if you can fully grasp onto all of this at once then you're a better person than I, but it's still a task worth attempting since it can let you meta analyze your life and your feelings and increase the chance that your decisions are made intentionally, which is nice because you have to live with them no matter what.

jfengel•6mo ago
Be wary of attempts to explain behavior via evolution. Not every trait is adaptive, so the right question is often not "What good does this do?" but "How did people survive despite this?"

Before attempting to apply such explanations, you'd need to have an extremely broad cultural perspective. Practically everybody you know is WEIRD (Western, Educated, Industrialized, Rich, and Democratic). You can't really draw a pattern without including a lot of other cultures, both existing and extinct.

yesfitz•6mo ago
How did people survive despite their predilection for revenge?
throwaway81523•6mo ago
Ideally by refraining from doing stuff makes other people vengeful toward them. I thought I saved a link about that but can't find it now.
thebeardisred•6mo ago
And the punchline?

> To help people safely release their revenge cravings and experiment with forgiveness, I’ve created a method known as the Nonjustice System that’s contained in my book and in the free Miracle Court app.

"Buy into my self-help program"