Patient-Specific in Vivo Gene Editing to Treat a Rare Genetic Disease

https://www.nejm.org/doi/full/10.1056/NEJMoa2504747

1•richardboegli•1m ago•0 comments

First Patient Treated with Personalized CRISPR Gene Editing Therapy

https://www.chop.edu/news/worlds-first-patient-treated-personalized-crispr-gene-editing-therapy-childrens-hospital

1•richardboegli•4m ago•0 comments

Reddit users in the UK must now upload selfies to access NSFW subreddits

https://mashable.com/article/reddit-age-verification-check-uk-law-online-safety

3•echelon•10m ago•0 comments

The Seductions of A.I. For the Writer's Mind

https://www.nytimes.com/2025/07/18/opinion/ai-chatgpt-school.html

1•pseudolus•19m ago•1 comments

Mr Browser – Macintosh Repository file downloader that runs directly on 68k Macs

https://www.macintoshrepository.org/44146-mr-browser

1•zdw•22m ago•0 comments

Tokyo's retro shotengai arcades are falling victim to gentrification

https://www.theguardian.com/world/2025/jul/18/cult-of-convenience-how-tokyos-retro-shotengai-arcades-are-falling-victim-to-gentrification

2•pseudolus•26m ago•0 comments

Control issues and ditching involving RPA swarm of 500 Damoda Newton 2.2 RPA

https://www.atsb.gov.au/publications/investigation_reports/2025/report/ao-2023-033

1•oliverdunk•29m ago•0 comments

Intel Announces It's Shutting Down Clear Linux

https://www.phoronix.com/news/Intel-Ends-Clear-Linux

5•gpi•31m ago•0 comments

Microsoft to stop using engineers in China for tech support of US Military

https://www.reuters.com/world/us/microsoft-stop-using-engineers-china-tech-support-us-military-hegseth-orders-2025-07-18/

4•miles•32m ago•0 comments

Playing Online Nintendo 64 Games with a Flashcart [video]

https://www.youtube.com/watch?v=v9aVrBq0aiY

5•giovannibajo1•33m ago•0 comments

Debcraft – Easiest way to modify and build Debian packages

https://optimizedbyotto.com/post/debcraft-easy-debian-packaging/

3•pabs3•38m ago•0 comments

Were Americans ever really healthy?

https://www.bloomberg.com/news/features/2025-07-18/was-the-us-ever-healthy-what-maha-gets-wrong-about-nutrition-history

2•zinekeller•39m ago•0 comments

How to Write Great Prompts for String

https://pipedream.com/blog/how-to-write-great-prompts-for-string/

1•todsacerdoti•41m ago•0 comments

Reinventing the Python Wheel

https://lwn.net/Articles/1028299/

1•zahlman•46m ago•0 comments

Why don't I drink? How much time you got?

https://shaungallagher.pressbin.com/blog/drinking.html

3•jawns•46m ago•0 comments

"Far out, man": how Jimi Hendrix boosted the career of Sha Na Na (2024)

https://faroutmagazine.co.uk/how-jimi-hendrix-boosted-the-career-of-sha-na-na

2•thomassmith65•48m ago•0 comments

Build an AI Agent Web App with String and Lovable

https://pipedream.com/blog/build-an-ai-agent-with-string-lovable/

1•todsacerdoti•48m ago•0 comments

Cascading retrieval with multi-vector representations

https://www.pinecone.io/blog/cascading-retrieval-with-multi-vector-representations/

1•gk1•54m ago•0 comments

What a bumble bee chooses to eat may not match its ideal diet

https://phys.org/news/2025-07-bumble-bee-ideal-diet.html

1•PaulHoule•55m ago•0 comments

Shutting Down Clear Linux OS

https://community.clearlinux.org/t/all-good-things-come-to-an-end-shutting-down-clear-linux-os/10716

43•todsacerdoti•58m ago•22 comments

Nuxt Joins Vercel

https://vercel.com/blog/nuxtlabs-joins-vercel

1•rattray•1h ago•1 comments

The Kap Programming Language

https://kapdemo.dhsdevelopments.com/examples.html

2•thunderbong•1h ago•0 comments

A Software for One

https://www.jasonthorsness.com/30

2•jasonthorsness•1h ago•0 comments

Women Are Falling Behind in America's Return to the Office

https://www.wsj.com/lifestyle/careers/return-to-office-gender-gap-236392aa

5•bdev12345•1h ago•2 comments

Astronomer launches internal investigation after viral Coldplay video

https://www.cnn.com/2025/07/18/entertainment/coldplay-concert-kiss-cam-astronomer-investigation

2•bb88•1h ago•0 comments

Build your CV on Subreply as a LinkedIn alternative

https://subreply.com/lm

4•lcnmrn•1h ago•0 comments

Curse Not the King

https://daringfireball.net/2025/07/curse_not_the_king_cbs_colbert_trump

2•Bogdanp•1h ago•0 comments

The Physics of Dissonance (MinutePhysics) [video]

https://www.youtube.com/watch?v=tCsl6ZcY9ag

1•jerf•1h ago•0 comments

Billionaire Gabe Newell: pitching VCs makes no business sense

https://www.pcgamer.com/gaming-industry/multi-billionaire-gabe-newell-says-the-whole-startup-culture-of-pitching-vcs-for-capital-makes-no-business-sense-a-great-way-of-destroying-money-and-wasting-peoples-time/

7•e2e4•1h ago•0 comments

Ccusage: A CLI tool for analyzing Claude Code usage from local JSONL files

https://github.com/ryoppippi/ccusage

19•kristianp•1h ago•9 comments

Patient-Specific in Vivo Gene Editing to Treat a Rare Genetic Disease

First Patient Treated with Personalized CRISPR Gene Editing Therapy

Reddit users in the UK must now upload selfies to access NSFW subreddits

The Seductions of A.I. For the Writer's Mind

Mr Browser – Macintosh Repository file downloader that runs directly on 68k Macs

Tokyo's retro shotengai arcades are falling victim to gentrification

Control issues and ditching involving RPA swarm of 500 Damoda Newton 2.2 RPA

Intel Announces It's Shutting Down Clear Linux

Microsoft to stop using engineers in China for tech support of US Military

Playing Online Nintendo 64 Games with a Flashcart [video]

Debcraft – Easiest way to modify and build Debian packages

Were Americans ever really healthy?

How to Write Great Prompts for String

Reinventing the Python Wheel

Why don't I drink? How much time you got?

"Far out, man": how Jimi Hendrix boosted the career of Sha Na Na (2024)

Build an AI Agent Web App with String and Lovable

Cascading retrieval with multi-vector representations

What a bumble bee chooses to eat may not match its ideal diet

Shutting Down Clear Linux OS

Nuxt Joins Vercel

The Kap Programming Language

A Software for One

Women Are Falling Behind in America's Return to the Office

Astronomer launches internal investigation after viral Coldplay video

Build your CV on Subreply as a LinkedIn alternative

Curse Not the King

The Physics of Dissonance (MinutePhysics) [video]

Billionaire Gabe Newell: pitching VCs makes no business sense

Ccusage: A CLI tool for analyzing Claude Code usage from local JSONL files

Are We Cooked?

Patient-Specific in Vivo Gene Editing to Treat a Rare Genetic Disease

First Patient Treated with Personalized CRISPR Gene Editing Therapy

Reddit users in the UK must now upload selfies to access NSFW subreddits

The Seductions of A.I. For the Writer's Mind

Mr Browser – Macintosh Repository file downloader that runs directly on 68k Macs

Tokyo's retro shotengai arcades are falling victim to gentrification

Control issues and ditching involving RPA swarm of 500 Damoda Newton 2.2 RPA

Intel Announces It's Shutting Down Clear Linux

Microsoft to stop using engineers in China for tech support of US Military

Playing Online Nintendo 64 Games with a Flashcart [video]

Debcraft – Easiest way to modify and build Debian packages

Were Americans ever really healthy?

How to Write Great Prompts for String

Reinventing the Python Wheel

Why don't I drink? How much time you got?

"Far out, man": how Jimi Hendrix boosted the career of Sha Na Na (2024)

Build an AI Agent Web App with String and Lovable

Cascading retrieval with multi-vector representations

What a bumble bee chooses to eat may not match its ideal diet

Shutting Down Clear Linux OS

Nuxt Joins Vercel

The Kap Programming Language

A Software for One

Women Are Falling Behind in America's Return to the Office

Astronomer launches internal investigation after viral Coldplay video

Build your CV on Subreply as a LinkedIn alternative

Curse Not the King

The Physics of Dissonance (MinutePhysics) [video]

Billionaire Gabe Newell: pitching VCs makes no business sense

Ccusage: A CLI tool for analyzing Claude Code usage from local JSONL files