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I went back to Linux and it was a mistake

https://www.theverge.com/report/875077/linux-was-a-mistake
1•timpera•41s ago•1 comments

Octrafic – open-source AI-assisted API testing from the CLI

https://github.com/Octrafic/octrafic-cli
1•mbadyl•2m ago•1 comments

US Accuses China of Secret Nuclear Testing

https://www.reuters.com/world/china/trump-has-been-clear-wanting-new-nuclear-arms-control-treaty-...
1•jandrewrogers•2m ago•0 comments

Peacock. A New Programming Language

1•hashhooshy•7m ago•1 comments

A postcard arrived: 'If you're reading this I'm dead, and I really liked you'

https://www.washingtonpost.com/lifestyle/2026/02/07/postcard-death-teacher-glickman/
2•bookofjoe•8m ago•1 comments

What to know about the software selloff

https://www.morningstar.com/markets/what-know-about-software-stock-selloff
2•RickJWagner•12m ago•0 comments

Show HN: Syntux – generative UI for websites, not agents

https://www.getsyntux.com/
3•Goose78•13m ago•0 comments

Microsoft appointed a quality czar. He has no direct reports and no budget

https://jpcaparas.medium.com/ab75cef97954
2•birdculture•13m ago•0 comments

AI overlay that reads anything on your screen (invisible to screen capture)

https://lowlighter.app/
1•andylytic•14m ago•1 comments

Show HN: Seafloor, be up and running with OpenClaw in 20 seconds

https://seafloor.bot/
1•k0mplex•14m ago•0 comments

Tesla turbine-inspired structure generates electricity using compressed air

https://techxplore.com/news/2026-01-tesla-turbine-generates-electricity-compressed.html
2•PaulHoule•16m ago•0 comments

State Department deleting 17 years of tweets (2009-2025); preservation needed

https://www.npr.org/2026/02/07/nx-s1-5704785/state-department-trump-posts-x
2•sleazylice•16m ago•1 comments

Learning to code, or building side projects with AI help, this one's for you

https://codeslick.dev/learn
1•vitorlourenco•17m ago•0 comments

Effulgence RPG Engine [video]

https://www.youtube.com/watch?v=xFQOUe9S7dU
1•msuniverse2026•18m ago•0 comments

Five disciplines discovered the same math independently – none of them knew

https://freethemath.org
4•energyscholar•19m ago•1 comments

We Scanned an AI Assistant for Security Issues: 12,465 Vulnerabilities

https://codeslick.dev/blog/openclaw-security-audit
1•vitorlourenco•20m ago•0 comments

Amazon no longer defend cloud customers against video patent infringement claims

https://ipfray.com/amazon-no-longer-defends-cloud-customers-against-video-patent-infringement-cla...
2•ffworld•20m ago•0 comments

Show HN: Medinilla – an OCPP compliant .NET back end (partially done)

https://github.com/eliodecolli/Medinilla
2•rhcm•23m ago•0 comments

How Does AI Distribute the Pie? Large Language Models and the Ultimatum Game

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=6157066
1•dkga•24m ago•1 comments

Resistance Infrastructure

https://www.profgalloway.com/resistance-infrastructure/
3•samizdis•28m ago•1 comments

Fire-juggling unicyclist caught performing on crossing

https://news.sky.com/story/fire-juggling-unicyclist-caught-performing-on-crossing-13504459
1•austinallegro•28m ago•0 comments

Restoring a lost 1981 Unix roguelike (protoHack) and preserving Hack 1.0.3

https://github.com/Critlist/protoHack
2•Critlist•30m ago•0 comments

GPS and Time Dilation – Special and General Relativity

https://philosophersview.com/gps-and-time-dilation/
1•mistyvales•33m ago•0 comments

Show HN: Witnessd – Prove human authorship via hardware-bound jitter seals

https://github.com/writerslogic/witnessd
1•davidcondrey•33m ago•1 comments

Show HN: I built a clawdbot that texts like your crush

https://14.israelfirew.co
2•IsruAlpha•35m ago•2 comments

Scientists reverse Alzheimer's in mice and restore memory (2025)

https://www.sciencedaily.com/releases/2025/12/251224032354.htm
2•walterbell•38m ago•0 comments

Compiling Prolog to Forth [pdf]

https://vfxforth.com/flag/jfar/vol4/no4/article4.pdf
1•todsacerdoti•40m ago•0 comments

Show HN: Cymatica – an experimental, meditative audiovisual app

https://apps.apple.com/us/app/cymatica-sounds-visualizer/id6748863721
1•_august•41m ago•0 comments

GitBlack: Tracing America's Foundation

https://gitblack.vercel.app/
12•martialg•41m ago•1 comments

Horizon-LM: A RAM-Centric Architecture for LLM Training

https://arxiv.org/abs/2602.04816
1•chrsw•42m ago•0 comments
Open in hackernews

Gut Microbiota Modulation as a Precision Strategy Against Obesity

https://www.mdpi.com/1422-0067/26/13/6282
7•PaulHoule•6mo ago

Comments

ggm•6mo ago
Fecal transplant. The pre biotics are good, but it's changing the biota of the lower gut which I think does the magic.
toomuchtodo•6mo ago
The goal of course is to custom tailor probiotics in order to not need the fecal transplant to modulate. GLP-1s will get the weight off, this is what is needed to keep it off. Might not even need the GLP-1s eventually, just update the gut biome with the prescribed metabolic profile.
ggm•6mo ago
Pro and pre biotics have to transit the upper gut and stomach biome to get to lower gut to do their goodness. I consume both, and I am sure I feel better for it but from people I know with crohns and IBS the word is, fecal transplant gets you to a better place faster.

In my unscientific view based on a sample size of 1, resistant starch, which really just means starch like cooked spuds, pasta or rice which is allowed to go cold before eating (can be reheated, and remember cooked food goes off quickly so store it safely) or something like inulin (banana flour is rich in it) or acetic acid (vinegar) are easy ways to boost lower gut health, by providing inputs which favour the bacteria you want. You want a lower gut rich in buterate consumers.

If in 20 years time this cool, folksy self treatment is exploded, aside from being dead of old age, I won't care because i got to eat loads of potato lutkes, arancini, pasta reheats, yummy yoghurt and kefir and vinegary dressings on salad. Dying of old age eating nice food for no provable health upside? Fine with me!

toomuchtodo•6mo ago
Don't disagree with regards to the speed and efficacy of fecal transplants, they just don't scale is all.
ggm•6mo ago
The FDA approved oral FMT gelcaps in 2023. So, there's progress. That was to treat C. Diff.