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The New Playbook for Leaders [pdf]

https://www.ibli.com/IBLI%20OnePagers%20The%20Plays%20Summarized.pdf
1•mooreds•34s ago•0 comments

Interactive Unboxing of J Dilla's Donuts

https://donuts20.vercel.app
1•sngahane•1m ago•0 comments

OneCourt helps blind and low-vision fans to track Super Bowl live

https://www.dezeen.com/2026/02/06/onecourt-tactile-device-super-bowl-blind-low-vision-fans/
1•gaws•3m ago•0 comments

Rudolf Vrba

https://en.wikipedia.org/wiki/Rudolf_Vrba
1•mooreds•4m ago•0 comments

Autism Incidence in Girls and Boys May Be Nearly Equal, Study Suggests

https://www.medpagetoday.com/neurology/autism/119747
1•paulpauper•5m ago•0 comments

Wellness Hotels Discovery Application

https://aurio.place/
1•cherrylinedev•5m ago•1 comments

NASA delays moon rocket launch by a month after fuel leaks during test

https://www.theguardian.com/science/2026/feb/03/nasa-delays-moon-rocket-launch-month-fuel-leaks-a...
1•mooreds•6m ago•0 comments

Sebastian Galiani on the Marginal Revolution

https://marginalrevolution.com/marginalrevolution/2026/02/sebastian-galiani-on-the-marginal-revol...
1•paulpauper•9m ago•0 comments

Ask HN: Are we at the point where software can improve itself?

1•ManuelKiessling•9m ago•0 comments

Binance Gives Trump Family's Crypto Firm a Leg Up

https://www.nytimes.com/2026/02/07/business/binance-trump-crypto.html
1•paulpauper•10m ago•0 comments

Reverse engineering Chinese 'shit-program' for absolute glory: R/ClaudeCode

https://old.reddit.com/r/ClaudeCode/comments/1qy5l0n/reverse_engineering_chinese_shitprogram_for/
1•edward•10m ago•0 comments

Indian Culture

https://indianculture.gov.in/
1•saikatsg•13m ago•0 comments

Show HN: Maravel-Framework 10.61 prevents circular dependency

https://marius-ciclistu.medium.com/maravel-framework-10-61-0-prevents-circular-dependency-cdb5d25...
1•marius-ciclistu•13m ago•0 comments

The age of a treacherous, falling dollar

https://www.economist.com/leaders/2026/02/05/the-age-of-a-treacherous-falling-dollar
2•stopbulying•13m ago•0 comments

Ask HN: AI Generated Diagrams

1•voidhorse•16m ago•0 comments

Microsoft Account bugs locked me out of Notepad – are Thin Clients ruining PCs?

https://www.windowscentral.com/microsoft/windows-11/windows-locked-me-out-of-notepad-is-the-thin-...
3•josephcsible•16m ago•0 comments

Show HN: A delightful Mac app to vibe code beautiful iOS apps

https://milq.ai/hacker-news
5•jdjuwadi•19m ago•1 comments

Show HN: Gemini Station – A local Chrome extension to organize AI chats

https://github.com/rajeshkumarblr/gemini_station
1•rajeshkumar_dev•19m ago•0 comments

Welfare states build financial markets through social policy design

https://theloop.ecpr.eu/its-not-finance-its-your-pensions/
2•kome•23m ago•0 comments

Market orientation and national homicide rates

https://onlinelibrary.wiley.com/doi/10.1111/1745-9125.70023
4•PaulHoule•23m ago•0 comments

California urges people avoid wild mushrooms after 4 deaths, 3 liver transplants

https://www.cbsnews.com/news/california-death-cap-mushrooms-poisonings-liver-transplants/
1•rolph•24m ago•0 comments

Matthew Shulman, co-creator of Intellisense, died 2019 March 22

https://www.capenews.net/falmouth/obituaries/matthew-a-shulman/article_33af6330-4f52-5f69-a9ff-58...
3•canucker2016•25m ago•1 comments

Show HN: SuperLocalMemory – AI memory that stays on your machine, forever free

https://github.com/varun369/SuperLocalMemoryV2
1•varunpratap369•26m ago•0 comments

Show HN: Pyrig – One command to set up a production-ready Python project

https://github.com/Winipedia/pyrig
1•Winipedia•28m ago•0 comments

Fast Response or Silence: Conversation Persistence in an AI-Agent Social Network [pdf]

https://github.com/AysajanE/moltbook-persistence/blob/main/paper/main.pdf
1•EagleEdge•28m ago•0 comments

C and C++ dependencies: don't dream it, be it

https://nibblestew.blogspot.com/2026/02/c-and-c-dependencies-dont-dream-it-be-it.html
1•ingve•28m ago•0 comments

Show HN: Vbuckets – Infinite virtual S3 buckets

https://github.com/danthegoodman1/vbuckets
1•dangoodmanUT•29m ago•0 comments

Open Molten Claw: Post-Eval as a Service

https://idiallo.com/blog/open-molten-claw
1•watchful_moose•29m ago•0 comments

New York Budget Bill Mandates File Scans for 3D Printers

https://reclaimthenet.org/new-york-3d-printer-law-mandates-firearm-file-blocking
2•bilsbie•30m ago•1 comments

The End of Software as a Business?

https://www.thatwastheweek.com/p/ai-is-growing-up-its-ceos-arent
1•kteare•31m ago•0 comments
Open in hackernews

Gut Microbiota Modulation as a Precision Strategy Against Obesity

https://www.mdpi.com/1422-0067/26/13/6282
7•PaulHoule•6mo ago

Comments

ggm•6mo ago
Fecal transplant. The pre biotics are good, but it's changing the biota of the lower gut which I think does the magic.
toomuchtodo•6mo ago
The goal of course is to custom tailor probiotics in order to not need the fecal transplant to modulate. GLP-1s will get the weight off, this is what is needed to keep it off. Might not even need the GLP-1s eventually, just update the gut biome with the prescribed metabolic profile.
ggm•6mo ago
Pro and pre biotics have to transit the upper gut and stomach biome to get to lower gut to do their goodness. I consume both, and I am sure I feel better for it but from people I know with crohns and IBS the word is, fecal transplant gets you to a better place faster.

In my unscientific view based on a sample size of 1, resistant starch, which really just means starch like cooked spuds, pasta or rice which is allowed to go cold before eating (can be reheated, and remember cooked food goes off quickly so store it safely) or something like inulin (banana flour is rich in it) or acetic acid (vinegar) are easy ways to boost lower gut health, by providing inputs which favour the bacteria you want. You want a lower gut rich in buterate consumers.

If in 20 years time this cool, folksy self treatment is exploded, aside from being dead of old age, I won't care because i got to eat loads of potato lutkes, arancini, pasta reheats, yummy yoghurt and kefir and vinegary dressings on salad. Dying of old age eating nice food for no provable health upside? Fine with me!

toomuchtodo•6mo ago
Don't disagree with regards to the speed and efficacy of fecal transplants, they just don't scale is all.
ggm•6mo ago
The FDA approved oral FMT gelcaps in 2023. So, there's progress. That was to treat C. Diff.